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Toxicity Assessment of Tetrabromobisphenol A with the Benthic Amphipod, Hyalella azteca  

Lee, Chul-Woo (Environmental Exposure Assessment Division, National Institute of Environmental Research)
Song, Sang-Hwan (Environmental Exposure Assessment Division, National Institute of Environmental Research)
Kim, Hyun-Mi (Environmental Exposure Assessment Division, National Institute of Environmental Research)
Kim, Hak-Joo (Environmental Exposure Assessment Division, National Institute of Environmental Research)
Choi, Kyung-Hee (Environmental Exposure Assessment Division, National Institute of Environmental Research)
Lee, Moon-Soon (Environmental Exposure Assessment Division, National Institute of Environmental Research)
Publication Information
Environmental Analysis Health and Toxicology / v.22, no.2, 2007 , pp. 157-163 More about this Journal
Abstract
Tetrabromobisphenol A (TBBPA) is the most widely used BFR (brominated flame retardants) as a reactive flame retardant in printed circuit boards, and as additive applications in several types of polymers. The purpose of this study is to assess the adverse effects of TBBPA on the benthic amphipod (Hyalella azteca). Results on the acute toxicity of TBBPA using Hyalella azteca showed that NOEC and LOEC are 100mg/kg and 200mg/kg, respectively. In addition, when chronic toxicity of TBBPA was investigated at the concentration ranges between 0.01 to 100mg/kg, it was found that NOECs are $10mg/kg(fecundity){\sim}100mg/kg(viability)$, respectively. Significant fecundity inhibition was appeared at 100mg/kg of TBBPA, however, this concentration did not show severe adverse effect on weight increment. The values of PNEC were determined as 0.1mg/kg (fecundity) and 1mg/kg (lethal effect), respectively, using a safety factor suggested by EU and OECD.
Keywords
Tetrabromobisphenol A(TBBPA); Brominated flame retardant; Hyalella azteca;
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