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Toxicity of Binary Mixture of Cyanide and 3,5-dichlorophenol to Vibrio fischeri Determined by Newly Developed $N-tox^{(R)}$ Bioassay System  

Lee, Jung-Suk (Institute of Environmental Protection and Safety, NeoEnBiz Co.)
Lee, Kyu-Tae (Institute of Environmental Protection and Safety, NeoEnBiz Co.)
Kim, Chan-Kook (Institute of Environmental Protection and Safety, NeoEnBiz Co.)
Kim, Hye-Jin (Institute of Environmental Protection and Safety, NeoEnBiz Co.)
Lee, Chang-Hoon (Institute of Environmental Protection and Safety, NeoEnBiz Co.)
Lee, Jong-Hyeon (Institute of Environmental Protection and Safety, NeoEnBiz Co.)
Publication Information
Environmental Analysis Health and Toxicology / v.22, no.1, 2007 , pp. 27-36 More about this Journal
Abstract
Cyanides and dichlorophenols were important pollutants in industrial effluents of steel, petroleum, plastics, pesticides, synthetic dye and/or fiber manufacturing. The toxic effects of cyanide and 3, 5-dichlorophenol in the unary and binary solutions to Vibrio fischeri were determined using the newly developed $N-tox^{(R)}$ bioassay system. This bioassay system relies upon the attenuation of light intensity emitted by Vibrio fischeri exposed to various pollutants including metals and organic compounds. Most of studies dealing with toxicity of pollutants concerned single chemical species, while the organisms were typically exposed to pollutant mixtures. The present study showed that the toxicity of some binary combinations of cyanide and 3, 5-dichlorophenol significantly was lower than the predicted toxicity from the addicted model. This antagonistic interaction was well explained by chemical interaction model presented in this study.
Keywords
Vibrio fischeri; bioassay; toxicity of pollutant mixture;
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