Evaluation of the Genetic Toxicity of Synthetic Chemicals (Ⅵ) -In vitro Chromosomal Aberration Assay with 17 Chemicals in Chinese Hamster Lung Cells - |
Ryu, Jae-Chun
(Toxicology Laboratory, Korea Institute of Science and Technology)
Kim, Kyung-Ran (Toxicology Laboratory, Korea institute of Science and Technology) Kim, Youn-Jung (Toxicology Laboratory, Korea Institute of Science and Technology) Jeon, Hee-Kyung (Toxicology Laboratory, Korea Institute of Science and Technology) |
1 | Ames BN, Durston WE, Yamasaki E and Lee FD. Carcinogens are mutagens : a simple test system combining liver homogenates for activation and bacteria for detection, Proc. Natl. Acad. Sci. USA 1973; 70: 2281-2285 DOI ScienceOn |
2 | Hayashi M, Sofuni T and Ishidate M Jr. High sensitivity in micronucleus induction of mouse strain, Mutation Res 1982; 105: 252-256 |
3 | Hayashi M, Kodama Y, Awogi T, Suzuki T, Asita AO and Sofuni T. The micronucleus assay using peripheral blood reticulocytes from mitomycin C- and cyclophosphamide-treated rats, Mutation Res 1992; 278: 209-213 DOI ScienceOn |
4 | Henderson L, Jones E, Freemantle M, Howard CA, Jenkinson P, Lambert R, Mackay J, Marshall R and Wilcox P. Extended harvest times are not necessary for the detection of in vitro clastogens in regulatory cytogenetics studies, Mutagenesis 1996; 11: 61-67 DOI ScienceOn |
5 | Ishidate M and Odashima S. Chromosome test with 134 compounds on chinese hamster cells in vitro-A screening for chemical carcinogens, Mutation Res 1977; 48: 337-354 DOI |
6 | JEMS-MMS Atlas of chromosome aberration by chemicals, Japanese Environmental Mutagen Society-Mammalian Mutagenicity Study Group. Tokyo 1998 |
7 | Maron DM and Ames BN. Revised methods for the Salmonella mutagenicity test, Mutation Res 1983; 113: 173-215 DOI |
8 | McCann J, Choi E, Yamasaki E and Ames BN. Detection of carcinogens as mutagens in the Salmonella/microsome test : assay of 300 chemicals, Proc Natl Acad Sci USA 1975; 72: 5135-5139 DOI ScienceOn |
9 | Mersch-Sundermann VS, Kerekordes S and Mochayedi S. Sources of variability of the Escherichia coli PQ 37 genotoxicity assay (SOS chromotest), Mutation Res 1991; 252: 51-60 DOI |
10 | Ryu J-C, Kim S-H, Kim K-R, Lee S, Kim M, Jung H-K and Park J. A study on the antimutagenic effect of cinnamic acid derivatives in Escherichia coli PQ 37 (SOS Chromotest) (I), Environ Mutagens & Carcinogens 1993b; 13: 8-17 |
11 | Ryu J-C, Lee S, Kim K-R and Park J. Evaluation of the genetic toxicity of synthetic chemicals (I). Chromosomal aberration test on chinese hamster lung cells in vitro, Environ Mutagens & Carcinogens 1994; 14: 138 - 144 |
12 | Ryu J-C, Kim H-J, Seo Y-R and Kim K-R. Single cell gel electrophoresis (comet assay) to detect DNA damage and apoptosis in cell level, Environ Mutagens & Carcinogens 1997; 17: 71-77 |
13 | Ryu J-C, Kim K-R, Kim H-J, Jung S-O, Kim M-K, Park H-S and Kim Y-H. Acute and Genetic Toxicity Study of DK 1002, a Drug Candidate for Analgesics, J Toxicol Pub Health 1998a; 14(3): 427-433 |
14 | Ryu J-C, Youn J-Y, Cho K-H and Chang I-M. Mutation spectrum in lac I gene of transgenic Big Blue cell line following to short term exposure 4-nitroquinoline N-oxide, Environ Mol Mutagenesis 1998d; 31(29): p. 16 |
15 | Ryu J-C, Kim K-R and Choi Y-J. In vitro mouse lymphoma thymidine kinase (tk+/-) gene forward mutation assay in mammalian cells, Environ Mutagen & Carcinogen 1999a; 19(1): 7-13 |
16 | Ryu J-C, Seo Y-R, Smith MA and Han SS. The Effect of methyl methanesulfonate (MMS)-induced excision repair on p53-dependent apoptosis in human lymphoid cells, Res Comm Mol Pathol and Pharmacol 2001 a; 109(1,2): 35-51 |
17 | Ryu J-C, Kim K-R, Lee S and Park J. Evaluation of the genetic toxicity of synthetic chemicals (III), Chromosomal aberration assay with 28 chemicals in chinese hamster lung cells in vitro, Environ Mutagens & Carcinogens 2001b; 21(1): 14-22 |
18 | Ryu J-C, Kim KR and Kim YJ. Evaluation of the Genetic Toxicity of Synthetic Chemicals (IV) - in vitro chromosomal aberration assay with 18 chemicals in Chinese hamster lung cells-, Environ Mutagens & Carcinogens 2002c; 22(3): 149-156 |
19 | Sato T, Chikazawa K, Yamamori H, Ose Y, Nagase H. and Kito H. Evaluation of the SOS chromotest for the detection of antimutagens, Environ Mol Mutagenesis 1991; 17: 258-263 DOI ScienceOn |
20 | Schmid W. The micronucleus test, Mutation Res 1975; 31: 9-15 DOI |
21 | Singh PN, Stephens RE and Schneider EL. Modification of alkaline microgel electrophoresis for sensitive detection of DNA damage, Int J Radiation Biol 1994; 66: 23-28 DOI ScienceOn |
22 | Tice RR, Agurell E, Anderson D, Burlinson B, Hartmann A, Kobayashi H, Miyamae Y, Rojas E, Ryu J-C and Sasaki YF. Single cell gel/comet assay: Guidelines for in vitro and in vivo genetic toxicology testing., Environ Mol Mutagenesis 2000; 35(3): 206-221 DOI ScienceOn |
23 | Ryu J-C, Kim K-R, Kim H-J, Ryu E-K, Lee S-Y, Jung S-O, Youn J-Y, Kim M-H and Kwon O-S. Evaluation of the genetic toxicity of synthetic chemicals (II). a pyrethroid insecticide, fenpropathrin, Arch Pharm Res 1996a; 19: 251-257 DOI ScienceOn |
24 | Clive D, McCuen R, Spector JFS, Piper C and Mavournin KH. Specific gene mutations in L5178Y cells in culture: A report of the U.S. Environmental Protection Agency Gen-Tox Program, Mutation Res 1983; 115: 225-251 DOI |
25 | Ryu J-C, Kim Y-J and Chai Y-G. Mutation spectrum of 1, 2-dibromo-3-chloropropane, an endocrine disruptor, in the lac I tranasgenic Big Blue Rat2 fibroblast cell line, Mutagenesis 2002a; 17(4): 301-307 DOI ScienceOn |
26 | Ryu J-C, Kim K-R, Kim H-J, Myung S-W, Kim G-H, Lee M-J and Chang I-M. Genotoxicity Study of Bojungchisup-tang, an oriental herbal decoction-in vitro chromosome aberration assay in chinese hamster lung cells and in vitro supravital-staining micronucleus assay with mouse peripheral reticulocytes, Arch Pharm Res 1998b; 21(4): 391-397 DOI ScienceOn |
27 | Ryu J-C, Kim KR, Kim YJ and Choi HY. Evaluation of the Genetic Toxicity of Synthetic Chemicals (V) - in vitro chromosomal aberration assay with 17 chemicals in Chinese hamster lung cells-, Environ Mutagens & Carcinogens, 2002d; 22(4): 215-222 |
28 | Ames BN, McCann J and Yamasaki E. Method for detecting carcinogens and mutagens with Salmonella/mammalian-microsome mutagenicity test, Mutation Res 1975; 31: 347-364 DOI |
29 | Kim Y-J, Park H-J, Kim Y, Kim M-K, Lee S-H, Jung S-H and Ryu J-C. Genotoxicity Study of sophoricoside. A constituent of Sophora japonica, in bacterial and mammalian cell system, Environmental Mutagens & Carcinogens 2001; 21(2): 99-105 |
30 | Mosmann T. Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays, J Immunol Methods 1983; 65: 55 -63 DOI PUBMED ScienceOn |
31 | Ryu J-C, Youn J-Y, Kim Y-J, Kwon O-S, Kim Y-S, H-T, Cho K-H and Chang I-M. Mutation spectrum of 4-nitroquinoline N-oxide in the lac I transgenic Big Blue Rat2 cell line, Mutation Res 1999b; 445: 127-135 DOI |
32 | Ryu J-C, Youn J-Y, Kim, Cho K-H and Chang I-M. Transgenic Mutagenesis assay to elucidate the mechanism of mutation in gene level, Environ Mutagen & Carcinogen 1998c; 18(1): 1-7 DOI ScienceOn |
33 | Ryu J-C, Kim Y-J, Kim H-T and Chai Y-G. Genotoxicity Assessment of atrazine in the Big Blue rat2 lac I transgenic cell line, Environ Mol Mutagenesis 2000; 35(31): p. 52 (No. 176) |
34 | Ryu J-C and Park KY. Anticlastogenic effect of Baechu (Chinese cabbage) Kimchi and Buchu (leek) Kimchi in supravital staining micronucleus assay using peripheral reticulocytes of mouse, Environ Mutagens & Carcinogens 2001c; 21(1): 51-56 |
35 | Suzuki T, Hayashi M, Sofuni T and Myhr BC. The concomitant detection of gene mutation and micronucleus induction by mitomycin C in vivo using lac Z transgenic mice, Mutation Res 1993; 285: 219-224 DOI |
36 | Zimmermann FK. Induction of mitotic gene conversion by mutagens, Mutation Res 1971; 11: 327-337 |
37 | Meselson M and Russell K. Comparison of carcinogenic and mutagenic potency. In Hiatt, H.H., Watson, J.D. and Winstend, J.A. (Eds.). Origin of Human Cancer. Cold Spring Harbor Laboratory, New York, 1991; pp. 1473-1481 |
38 | Hayashi M, Maki-Paakkanen J, Tanabe H, Honma M, Suzuki T, Matsuoka A, Mizusawa H and Sofuni T. Isolation of micronuclei from mouse blood and fluorescence in situ hybridization with a mouse centromeric DNA probe, Mutation Res 1994; 307: 245-251 DOI |
39 | Radman M, Jeggo P and Wagner R. Chromosomal rearrangement and carcinogenesis, Mutation Res 1982; 98: 249-264 DOI |
40 | Ryu J-C, Kim K-R, Ryu E-K, Kim H-J, Kwon O-S, Song C-E, Mar W and Chang I-M. Chromosomal aberration assay of taxol and 10-deacetyl baccatin III in chinese hamster lung cells in vitro, Environ Mutagens & Carcinogens 1996b; 16: 6-12 |
41 | Ryu J-C, Kim HT and Kim YJ. Studies on DNA single strand break of seven phthalate analogues in mouse lymphoma cells, Environ Mutagens & Carcinogens 2002b; 22(3): 164-168 |
42 | Heo MY, Kim JH and Ryu J-C. Anticlastogenicity of betacarotene and galangin using in vivo supravital staining micronucleus test, Environ. Mutagens & Carcinogens 1997; 17: 92-96 |
43 | Ryu J-C, Lee S, Kim K-R, Kim M, Chang I-M and Park J. A study on the clastogenicity of trichothecene mycotoxins in chinese hamster lung cells, Korean J Toxicol 1993a; 9: 13-21 |
44 | Ryu J-C. Introduction of Recent advanced cellular and Molecular Toxicology, Korean J Pesticide Science 2002f; 6(3): 157-165 |
45 | Sawyer J, Moore MM, Clive D and Hozier J. Cytogenetic characterization of the L5178Y TK+/- 3.7.2C mouse lymphoma cell line, Mutation Res 1985; 147: 243-253 DOI |
46 | OECD. OECD giudeline for the testing of chemicals, Documents 473, Genetic toxicology: in vitro mammalian cytogenetic test, Organization for Economic Cooperation and Development, Paris, France. 1993 |
47 | Ryu J-C. Current Trend of Advanced Methods in Cellular and Molecular Toxicology, Environ Mutagens & Carcinogens 2002e; 22(1): 1-11 |
48 | Altman DG. Comparing groups-categorical data : Practical Statistics for Medical Research. Chapman & Hall, London, 1993; 229-276 |
49 | Kohler SW, Provost GS, Fieck A, Kretz PL, Bullock WO, Sorge JA, Putman DL and Short JM. Spectra of spontaneous and mutagen-induced mutations in the lac I gene in transgenic mice, Proc Natl Acad Sci USA 1991; 88: 7958-7962 DOI ScienceOn |
50 | WHO. The evaluation and testing of drugs for mutagenicity, principles and problems, WHO Tech Rep Ser 1971; No. 482 |
51 | Galloway SM, Sofuni T, Shelby MD, Thilager A, Kumaroo V, Kaur P, Gulati D, Putman DL, Murli H, Marshall R, Tanaka N, Anderson B, Zeiger E and Ishidate M Jr. Multilaboratory comparison of in vitro tests for chromosome aberrations in CHO and CHL cells tested under the same protocols, Environ. Mol. Mutagenesis 1997; 29: 189-207 DOI ScienceOn |
52 | Hayashi M, Morita T, Kodama Y, Sofuni T and Ishidate M Jr. The micronucleus assay with mouse peripheral blood reticulocytes using acridine orange-coated slides, Mutation Res 1990; 245: 245-249 DOI ScienceOn |
53 | Ryu J-C, Kwon O-S and Kim H-T. Optimal conditions of Single Cell Gel Electrophoresis (Comet) Assay to detect DNA single strand breaks in mouse lymphoma L5178Y cells, Environ Mutagens & Carcinogens 2001d; 21(2): 89-94 |