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The Clinical Utility of Rectal Gas Distension F-18 FDG PET/CT  

Kim, Jin-Suk (Department of Nuclear Medicine, Chonbuk National University Medical School and Hospital)
Lim, Seok-Tae (Department of Nuclear Medicine, Chonbuk National University Medical School and Hospital)
Jeong, Young-Jin (Department of Nuclear Medicine, Chonbuk National University Medical School and Hospital)
Kim, Dong-Wook (Department of Nuclear Medicine, Chonbuk National University Medical School and Hospital)
Jeong, Hwan-Jeong (Department of Nuclear Medicine, Chonbuk National University Medical School and Hospital)
Sohn, Myung-Hee (Department of Nuclear Medicine, Chonbuk National University Medical School and Hospital)
Publication Information
Nuclear Medicine and Molecular Imaging / v.43, no.6, 2009 , pp. 565-571 More about this Journal
Abstract
Purpose: The aim of this study was to evaluate the clinical value of rectal gas distension F-18 FDG PET/CT imaging for the differentiation of the rectal focal uptake lesions. Materials and Methods: Twenty four patients (M:F=11:13, Age $62.8{\pm}12.4$ years) underwent rectal gas distension F-18 FDG PET/CT, prospectively: initial image at 50-60 min after the intravenous injection of F-18 FDG and rectal distension image after the infusion of air through the anus. Focally increased uptake lesions on initial images but disappeared on rectal distension images defined a physiological uptake. For the differential evaluation of persistent focal uptake lesions on rectal distension images, colonoscopy and histopathologic examination were performed. Results: Among the 24 patients, 27 lesions of focal rectal uptake were detected on initial images of F-18 FDG PET/CT. Of these, 7 lesions were able to judge with physiological uptake because the focal increased uptake disappeared from rectal distension image. Remaining 3 lesions were non-rectal lesions (2 lesions: rectovesical space, 1 lesion: uterine myoma). Among 17 lesions which was showed persistent increased uptake in rectal distension image, 15 lesions were confirmed as the malignant tumor (SUVmax=$15.9{\pm}6.8$) and 2 lesions were confirmed as the benign lesions including adenoma and inflammatory disease. Conclusion: The rectal distension F-18 FDG PET/CT imaging could be an important noninvasive method for the differentiation of malignant and benign focal rectal uptake lesions including physiologic uptake.
Keywords
Rectal distension image; F-18 FDG; PET/CT;
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