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Incidental Benign Parotid Lesions on FDG-PET: Prevalence and Clinico-pathologic Findings  

Lim, Il-Han (Department of Nuclear Medicine, Seoul National University College of Medicien, Seoul National University Bundang Hospital)
Lee, Won-Woo (Department of Nuclear Medicine, Seoul National University College of Medicien, Seoul National University Bundang Hospital)
Chung, Jin-Haeng (Department of Pathology, Seoul National University College of Medicine, Seoul National University Bundang Hospital)
Park, So-Yeon (Department of Nuclear Medicine, Seoul National University College of Medicien, Seoul National University Bundang Hospital)
Kim, Sang-Hee (Department of Nuclear Medicine, Seoul National University College of Medicien, Seoul National University Bundang Hospital)
Kim, Yu-Kyeong (Department of Nuclear Medicine, Seoul National University College of Medicien, Seoul National University Bundang Hospital)
Kim, Sang-Eun (Department of Nuclear Medicine, Seoul National University College of Medicien, Seoul National University Bundang Hospital)
Publication Information
Nuclear Medicine and Molecular Imaging / v.41, no.5, 2007 , pp. 359-363 More about this Journal
Abstract
Purpose: Incidental parotid lesions on F-18 FDG-PET can mimic distant metastasis of underlying malignancy. The prevalence and the clinico-pathologic findings of PET positive parotid lesions have not been known. We investigated how often incidental parotid lesions are found on clinical FDG-PET studies and what the clinico-pathologic characteristics of those parotid lesions are in the present study. Materials and Methods: We retrospectively reviewed 3,344 cases of FDG-PET which had been obtained in our hospital from May 2003 to Dec 2006. The indications of FDG-PET were: evaluation of known/suspected cancer (n= 3,212) or screening of cancer in healthy subjects (n=132). Incidental parotid lesion on FDG-PET was defined as an un-expected FDG uptake in one of parotid glands which was not primary target lesion of current FDG-PET. FDG uptake was represented by maximum standardized uptake value (maxSUV). Final diagnosis was made by pathologic analysis or clinical follow-up assessment. Results: Fifteen (0.45% = 15/3,344) incidental parotid lesions were found and they were all benign lesions. The maxSUV ranged from 1.7 to 8.6 (mean${\pm}$s.d. = $3.7{\pm}1.9$). Final diagnoses of the incidental parotid lesions were; Warthin's tumor (n=2), pleomorphic adenoma (n=1), other un-specified benign lesion (n=1), and benign lesions under bases of imaging studies (n=3) and of clinical follow-up (n=8). Conclusion: All of incidentally found parotid lesions in clinical FDG-PET studies were confirmed as benign lesions with prevalence of 0.45%. Close follow up using PET or CT might be a reasonable approach for determining the nature of incidentally found parotid lesions.
Keywords
FDG-PET; parotid gland; incidentaloma;
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