Development of Dual Reporter System of Mutant Dopamine 2 Receptor () and Sodium Iodide Symporter (NIS) Transgenes |
Hwang, Do-Won
(Program in Neuroscience, Seoul National University)
Lee, Dong-Soo (Program in Neuroscience, Seoul National University) Kang, Joo-Hyun (Department of Nuclear Medicine, Seoul National University College of Medicine) Chang, Young-Soo (Department of Nuclear Medicine, Seoul National University College of Medicine) Kim, Yun-Hui (Program in Neuroscience, Seoul National University) Jeong, Jae-Min (Department of Nuclear Medicine, Seoul National University College of Medicine) Chung, June-Key (Department of Nuclear Medicine, Seoul National University College of Medicine) Lee, Myung-Chul (Department of Nuclear Medicine, Seoul National University College of Medicine) |
1 | Herschman HR, MacLaren DC, Iyer M, Namavari M, Bobinski K, Green LA, et al. Seeing is believing: non-invasive, quantitative and repetitive imaging of reporter gene expression in living animals, using positron emission tomography. Neurosci Res 2000;15:699-705 |
2 | Min JJ, Chung JK, Lee YJ, Shin JH, Yeo JS, Jeong JM, et al. In vitro and in vivo characteristics of a human colon cancer cell line, SNU-C5N, expressing sodium-iodide symporter. Nucl Med Biol 2002;29:537-45 DOI ScienceOn |
3 | Barrio JR, Satyamurthy N, Huang SC, Keen RE, Nissenson CH, Hoffman JM, et al. 3-(2'-[]fluoroethyl)spiperone: in vivo biochemical and kinetic characterization in rodents, nonhuman primates, and humans. J Cereb Blood Flow Metab 1989;9:830-9 DOI PUBMED |
4 | Bahn MM, Huang SC, Hawkins RA, Satyamurthy N, Hoffman JM, Barrio JR, et al. Models for in vivo kinetic interactions of dopamine D2-neuroreceptors and 3-(2'-[]fluoroethyl)spiperone examined with positron emission tomography. J Cereb Blood Flow Metab 1989;9:840-9 DOI PUBMED |
5 | Chung JK. Sodium iodide symporter: its role in nuclear medicine. J Nucl Med 2002;43:1188-200 PUBMED |
6 | Shin JH, Chung JK, Kang JH, Lee YJ, Kim KI, Kim CW. Feasibility of sodium/iodide symporter gene as a new imaging reporter gene: comparison with HSV1-tk. Eur J Nucl Med Mol Imaging 2004;31:425-32 DOI PUBMED |
7 | Palacios JM, Niehoff DS, Kuhar MJ. []spiperone binding sites in brain: Autoradiographic localization of multiple receptors. Brain Research 1981;213:277-89 |
8 | MacLaren DC, Gambhir SS, Satyamurthy N, Barrio JR, Sharfstein S, Toyokuni T,etal. Repetitive, non-invasive imaging of the dopamine receptor as a reporter gene in living animals. Gene Thrapy 1999;6:785-91 DOI ScienceOn |
9 | Gurtu V, Yan G, Zhang G. IRES bicistronic expression vectors for efficient creation of stable mammalian cell lines. Biochem Biophys Res Commun 1996;229:295-8 DOI ScienceOn |
10 | Adonai N, Nguyen KN, Walsh J, Iyer M, Toyokuni T, Phelps ME, et al. Ex vivo cell labeling with -pyruvaldehyde-bis(N4-methylthiosemicarbazone) for imaging cell trafficking in mice with positron-emission tomography. Proc Natl Acad Sci U S A 2002;99:3030-5 DOI ScienceOn |
11 | Vile JM, D'Souza UM, Strange PG. []nemonapride and []spiperone label equivalent numbers of D2 and D3 dopamine receptors in a range of tissues and under different conditions. J Neurochem 1995;64:940-3 DOI PUBMED ScienceOn |
12 | Yaghoubi SS, Wu L, Liang Q, Toyokuni T, Barrio JR, Namavari M, et al. Direct correlation between positron emission tomographic images of two reporter genes delivered by two distinct adenoviral vectors. Gene Thrapy 2001;8:1072-80 DOI ScienceOn |
13 | Woodward R, Coley C, Daniell S, Naylor LH, Strange PG. Investigation of the role of conserved serine residues in the long form of the rat D2 dopamine receptor using site-directed mutagenesis. J Neurochem 1996;66:394-402 DOI PUBMED ScienceOn |
14 | Yu Y, Annala AJ, Barrio JR, Toyokuni T, Satyamurthy N, Namavari M, et al. Quantification of target gene expression by imaging reporter gene expression in living animals. Nature Medicine 2000;6:933-7 DOI ScienceOn |
15 | Dai G, Levy O, Carrasco N. Cloning and characterization of the thyroid iodide transporter. Nature 1996;379:458-60 DOI ScienceOn |
16 | Gambhir SS, Barrio JR, Herschman HR, Phelps ME. Assays for noninvasive imaging of reporter gene expression. Nucl Med Biol 1999;26:481-90 DOI ScienceOn |
17 | Missale C, Nash SR, Robinson SW, Jaber M, Caron MG. Dopamine receptors: from structure to function. Physiol Rev 1998;78:189-225 DOI PUBMED |
18 | Liang Q, Satyamurthy N, Barrio JR, Toyokuni T, Phelps MP. Noninvasive, quantitative imaging in living animals of a mutant dopamine receptor reporter gene in which ligand binding is uncoupled from signal transduction. Gene Thrapy 2001;8:1490-98 DOI ScienceOn |
19 | Bunzow JR, Van Tol HH, Grandy DK, Albert P, Salon J, Christie M,etal. Cloning and expression of a rat D2 receptor cDNA. Nature 1988;336:783-7 DOI ScienceOn |
20 | Sun X, Annala AJ, Yaghoubi SS, Barrio JR, Nguyen KN, Toyokuni T, et al. Quantitative imaging of gene induction in living animals. Gene Thrapy 2001;8:1572-9 DOI ScienceOn |
21 | Satyamurthy N, Barrio JR, Bida GT, Huang SC, Mazziotta JC, Phelps ME. 3-(2'-[]fluoroethyl)spiperone, a potent dopamine antagonist: synthesis, structural analysis and in-vivo utilization in humans. Int J Rad Appl Instrum 1990;41:113-29 DOI ScienceOn |