Effect of Verapamil on Cellular Uptake of Tc-99m MIBI and Tetrofosmin on Several Cancer Cells |
Kim, Dae-Hyun
(Department of Nuclear Medicine, Kyungpook National University School of Medicine)
Yoo, Jung-Ah (Department of Nuclear Medicine, Kyungpook National University School of Medicine) Suh, Myung-Rang (Department of Nuclear Medicine, Kyungpook National University School of Medicine) Bae, Jin-Ho (Department of Nuclear Medicine, Kyungpook National University School of Medicine) Jeong, Shin-Young (Department of Nuclear Medicine, Kyungpook National University School of Medicine) Ahn, Byeong-Cheol (Department of Nuclear Medicine, Kyungpook National University School of Medicine) Lee, Kyu-Bo (Department of Nuclear Medicine, Kyungpook National University School of Medicine) Lee, Jae-Tae (Department of Nuclear Medicine, Kyungpook National University School of Medicine) |
1 | Hendrikse NH, Franssen EJF, van der Graaf WTA, Vaalburg W, de Vries EGE. Visualization of multidrug resistance in vivo. Eur J Nucl Med 1999;26:283-93 DOI ScienceOn |
2 | Rodrigues M, Kalinowska W, Zielinski C. Sinzinger H. Verapamil decreases accumulation of -MIBI-tetrofosmin in human breast cancer and soft tissue sarcoma cell lines. Nucl Med Comm 2001;22:645-50 DOI ScienceOn |
3 | Kostakoglu L, Elahi N, Kiratli P, Ruacan S, Sayek I, Baltali E. Clinical validation of the influence of P-glycoprotein on technetium-99m-sestamibi uptake in malignant tumors. J Nucl Med 1997;38:1003-8 PUBMED |
4 | Ballinger JR. Imaging multidrug resistance with radiolabeled substrates for P-glycoprotein and multidrug resistance protein. Cancer Biother Radiopharm 2001;16:1-7 DOI ScienceOn |
5 | Kim JK, Lee J, Lee BH, Choi SU, Lee SW, Chun KA, et al. Reversal of multidrug resistance with KR-30035: Evaluation with biodistribution of Tc-99m MIBI in nude mice bearing human tumor xenografts. Korean J Nucl Med 2001:35;168-84 |
6 | Cordobes MD, Starzec A, Delmon-Moingeon L, Blanchot C, Kouyoumdjian JC, Prevost G, et al. Technetium-99m-sestamibi uptake by human benign and malignant breast tumor cells: correlation with mdr gene expression. J Nucl Med 1996;37:286-9 PUBMED |
7 | Tunggal JK, Melo T, Ballinger JR, Tannock IF. The influence of expression of P-glycoprotein on the penetration of anticancer drugs through multicelluar layers. Int J Cancer 2000;86:101-7 DOI ScienceOn |
8 | Zheng B, Chambers TC, Raynor RL, Markham PN, Gebel MW, Vogler WR, et al. Human leukemia K562 cell mutant (K562/OA200) selected for resistance to okadaic acid (protein phosphatase inhibitor) lacks protein kinase C-, exhibits multidrug resistance phenotype, and expresses drug pump P-glycoprotein. J Biol Chem 1994;269:12332-8. PUBMED |
9 | Kao CH, Ho YJ, Shen YY, Lee JK. Evaluation of chemotherapy response in patients with small cell lung cancer using technetium-99m-tetrofosmin. Anticancer Res 1999;19:2311-5 PUBMED |
10 | Rodrigues M, Chehne F, Kalinowska W, Berghammer P, Zielinki C, Sinzinger H. Uptake of Tc-tetrofosmin into malignant versus nonmalignant breast cell line. J Nucl Med 2000;41:1495-9 PUBMED |
11 | Cory S, Adams JM. The bcl2 family: regulators of the cellular life-or-death switch. Nat Rev Cancer 2002;2:647-56 DOI ScienceOn |
12 | Taki J, Sumiya H, Asada N, Ueda Y, Tsuchiya H, Tonami N. Assessment of P-glycoprotein in patients with malignant bone and soft-tissue tumors using technetium-99m-MIBI scintigraphy. J Nucl Med 1998;39:1179-84 PUBMED |
13 | Lee J. Functional imaging of the multidrug resistance in vivo. Korean J Nucl Med 2001;35:66-75 |
14 | Ballinger JR, Hua BW, Berry BW, Firby P, Boxen I. Tc-sestamibi as an agent for imaging P-glycoprotein-mediated multi-drug resistance: in vitro and in vivo studies in a rat breast tumour cell line and its doxorubicin-resistant variant. Nucl Med Commun 1995;16:253-7 DOI PUBMED ScienceOn |
15 | Murray NR, Baumgardner GP, Burns DJ, Fields AP. Protein kinase C isotypes in human erythroleukemia (K562) cell proliferation and differentiation. J Biol Chem 1993;268:15847-53 PUBMED |
16 | Del Vecchio S, Zannetti A, Aloj L, Caraco C, Ciarmiello A, Salvatore M. Inhibition of early Tc-MIBI uptake by Bcl-2 anti-apoptotic protein overexpression in untreated breast carcinoma. Eur J Nucl Med Mol Imaging 2003;30:879-87 DOI PUBMED ScienceOn |
17 | Piwnica-Worms D, Chiu ML, Budding M, Kronauge JF, Kramer RA, Croop JM. Functional imaging of multidrug-resistant P-glycoprotein with an organotech-netium complex. Cancer Res 1993;53:977-84 PUBMED |
18 | Hardy SP, Goodfellow HR, Valverde MA, Grill DR, Sepulveda V, Higgins CF. Protein kinase C-mediated phosphorylation of the human multidrug resistance P-glycoprotein regulates cell volume-activated chloride channels. EMBO J 1995;14:68-75 PUBMED |
19 | Sikik BI. Pharmacologic approaches to reversing multidrug resistance. Semin Hematol 1997;34:40-7 |
20 | Breuninger LM, Paul S, Gaughan K, Miki T, Chan A, Aaronson SA. Expression of multidrug resistance associated protein with increased drug efflux and altered intracellular drug distribution. Cancer Res 1995;55:5342-7 PUBMED |
21 | Abraham EH, Prat AG, Gerweck L, Seneveratne T, Arceci RJ, Krarmer R, et al. The multidrug resistance (mdr1) gene product functions as an ATP channel. Proc Natl Acad Sci U S A 1993;90:312-6 DOI ScienceOn |
22 | Rodrigues M, Chehne F, Kalinowaka W, Zielinski C, Sinzinger H. Comparative Tc-furifosmin uptake in human soft tissue sarcoma cell lines. Eur J Nucl Med 2000;27:1839-43 DOI ScienceOn |
23 | Chun KA, Lee J, Lee SW, Kang DY, Sohn SK, Lee JK, et al. Effect of multidrug resistance gene-1 (mdr1) overexpression on in-vitro uptake of Tc-sestamibi in murine L1210 leukemia cells. Korean J Nucl Med 1999;33:152-62 |
24 | Rao VV, Chiu ML, Kronauge JF, Piwnica-Worms D. Expression of recombinant human multidrug resistance P-glycoprotein in insect cells confers decreased accumulation of technetium-99m-sestamibi. J Nucl Med 1994;35:510-5 PUBMED |
25 | Yoo JA, Chung SY, Seo MR, Kwak DS, Ahn BC, Lee KB, et al. Comparison of uptakes of Tc-tetrofosmin in cancer cell lines expressing multidrug resistance. Korean J Nucl Med 2003;37:178-89 |
26 | Utsunomiya K, Ballinger JR, Piquette-Miller M, Rauth AM, Tang W, Su ZF, et al. Comparison of the accumulation and efflux kinetics of technetium-99m sestamibi and technetium-99m tetrofosmin in an MRP-expressing tumour cell line. Eur J Nucl Med 2000;27:1786-92 DOI ScienceOn |
27 | Ding HJ, Shiau YC, Tsai SC, Wang JJ, Ho ST, Kao A. Uptake of Tc sestamibi. Appl Radiat Isot. 2002;56:853-6 DOI ScienceOn |
28 | Piwnica-Worms D, Rao VV, Krounage JF, Croop JM. Characterization of multidrug resistance transport function with an organotechnetium cation. Biochemistry 1995;34:12210-20 DOI ScienceOn |
29 | Soderlund V, Larsson SA, Bauer HCF, Brosjo O, Larsson O, Jacobson H. Use of Tc-MIBI scintigraphy in the evaluation of the response of osteosarcoma to chemotherapy. Eur J Nucl Med 1997;24:511-5 PUBMED |
30 | Arbab AS, Koizumi K, Toyama K, Araki T. Uptake of technetium-99m-tetrofosmin, technetium-99m-MIBI and thallium-201 in tumor cell lines. J Nucl Med 1996;37:1551-6 PUBMED |