Browse > Article

Osteogenic Sarcoma with Osseous, Pulmonary, and Pericardial Metastases Simultaneously Demonstrated on Bone Scintigraphy at Initial Presentation  

Lim, Seok-Tae (Departments of Nuclear Medicine, Chonbuk National University Medical School)
Kim, Min-Woo (Departments of Nuclear Medicine, Chonbuk National University Medical School)
Sohn, Myung-Hee (Departments of Nuclear Medicine, Chonbuk National University Medical School)
Hwang, Pyoung-Han (Departments of Pediatrics, Chonbuk National University Medical School)
Publication Information
The Korean Journal of Nuclear Medicine / v.37, no.5, 2003 , pp. 336-339 More about this Journal
Abstract
Purpose: A 6-year-old boy with osteogenic sarcoma of the left humerus underwent bone scintigraphy. Tc-99m MDP was accumulated not only in the primary tumor but also in the osseous and extraosseous (pulmonary and pericardial) metastases. Osteogenic sarcoma directly produces osteoid, both in the primary and metastatic lesions. Tc-99m MDP is avidly taken up by tumor osteoid. At initial presentation, only 2% of cases have both pulmonary and osseous metastases. The patient had osseous, pulmonary, and pericardial metastases at presentation. This case presents that increased uptakes of Tc-99m MDP by the primary and metastatic tumor were demonstrated on bone scintigraphy at presentation.
Keywords
Osteogenic sarcoma; metastases; extraosseous uptake; Tc-99m MDP; bone scintigraphy;
Citations & Related Records
연도 인용수 순위
  • Reference
1 Palestro CJ, Styles ST, Kim CK, Goldsmith SJ. Bone scintigraphy in pleural metastases of osteogenic sarcoma. Clin Nucl Med 1990;15: 346-7   DOI   PUBMED
2 Pace WM, Ross McDougall I. Tc-99m MDP uptake in soft tissue extraskeletal metastasis from osteogenic sarcoma. Clin Nucl Med 2000;25: 333-4   DOI   ScienceOn
3 Palestro CJ, Swyer AJ, Goldsmith SJ. Multiple extraosseous metastases from osteogenic sarcoma demonstrated on bone scintigraphy. Clin Nucl Med 1992;17: 746-8   DOI   PUBMED
4 Phillips CD, Williamson BR. Osteosarcoma with pericardial metastases seen on bone scan. Clin Nucl Med 1987;12: 899-900   DOI   PUBMED
5 Siddiqui AR, Ellis JH. “Cold spot” on bone scan at the site of primary osteosarcoma. Eur J Nucl Med 1982;7: 480-1   PUBMED
6 Babbel RW, Jackson DE, Conte FA. Technetium-99m MDP accumulation in a nonmalignant pleural effusion. Clin Nucl Med 1988;13: 298-9   DOI   PUBMED
7 Goldstein H, McNeil BJ, Zufall E, Jaffe N, Treves S. Changing indications for bone scintigraphy in patients with osteosarcoma. Radiology 1980;135:177-80   DOI   PUBMED
8 McKillop JH, Etcubanas E, Goris ML. The indications for and limitations of bone scintigraphy in osteogenic sarcoma: A review of 55 patients. Cancer 1981;48: 1133-8   DOI   ScienceOn
9 Velchik MG, Wegener W. Osteogenic sarcoma with pulmonary metastasis visualized by bone imaging. Clin Nucl Med 1989;14: 662-5   DOI   PUBMED
10 Arrington ER, Eisenberg B, Orrison WW Jr, Williamson MR. Scintigraphic appearance of uncommon soft-tissue osteogenic sarcoma metastases. J Nucl Med 1990;31: 679-81   PUBMED
11 Heinle A, Carrasquillo JA, Neumann RD. Two unusual cases of metastatic osteosarcoma detected by Tc-99m MDP bone scintigraphy. Clin Nucl Med 1989;14: 889-93   DOI   PUBMED