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http://dx.doi.org/10.14578/jkfs.2016.105.2.193

Bioactive Component Analysis, Antioxidant Activity, and Cytotoxicity on Cancer Cells on Rubus crataegifolius Clones by Region  

Choi, Eun-Young (Department of Cosmeceutical Science, Daegu Haany University)
Kim, Eun-Hee (Department of Cosmeceutical Science, Daegu Haany University)
Lee, Jae-Bong (Department of Cosmeceutical Science, Daegu Haany University)
Kim, Hyeu-soo (Division of Special Purpose Trees, National Institute of Forest Science)
Kim, Moon-Sup (Division of Special Purpose Trees, National Institute of Forest Science)
Lee, Su-gwang (Division of Special Purpose Trees, National Institute of Forest Science)
Kim, Sea-Hyun (Division of Special Purpose Trees, National Institute of Forest Science)
Lee, Uk (Division of Special Purpose Trees, National Institute of Forest Science)
Kim, Dong-Kwon (Korea Dyeing & Finishing Technology Institute Advanced Processing Development Center)
Lee, Jin-Tae (Department of Cosmeceutical Science, Daegu Haany University)
Publication Information
Journal of Korean Society of Forest Science / v.105, no.2, 2016 , pp. 193-201 More about this Journal
Abstract
This study was carried out to analyze the nutritional composition, bioactive components, antioxidant activity, and cytotoxic assay of cancer cells on Rubus crataegifolius (RC) : R. crataegifolius from Jangseong (RC-J), R. crataegifolius from Hwaseong (RC-H), R. crataegifolius from Ulsan (RC-U), R. crataegifolius from Sunchang (RC-S), and R. crataegifolius from Pohang (RC-P). The peroximate composition had the largest amount of carbohydrate content among all kinds of RC. As far as the mineral contents of RC, Calcium comprised the highest amount ($996.6{\mu}g/g{\pm}0.8%$) and Natrium the lowest ($6.2{\mu}g/g{\pm}1.0%$). A total of 26 kinds of free amino acids and 18 kinds of component amino acids were analyzed in RC. The results of electron donating were high scavenging effects of 80% in water extract (RC-UW) and 82.6% in ethanol extract (RC-UE) in $500{\mu}g/ml$ concentration from RC-U. Also, the cytotoxic effects of cancer cells B16F10 (RC-UW and RC-PE), H1299 (RC-SW and RC-PE), and MCF-7 (RC-JW and RC-SE) appeared in RC. Therefore, we confirmed that new varieties may possibly be developed with functional materials.
Keywords
amino acid; electron donating ability; mineral contents; MTT assay; peroximate composition; Rubus crataegifolius;
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Times Cited By KSCI : 10  (Citation Analysis)
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