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Study on Anti-oxidant Effect of Extracts from Pyrus ussuriensis Leaves  

Lee, Chang-Eon (Department of Cosmeceutical Science, Daegu Haany University)
Kim, Young-Hun (Skin Science R&D Center, Mediway Korea Co., Ltd.)
Lee, Byung-Guen (Department of Forest Resources, Yeungnam University)
Lee, Do-Hyung (Department of Forest Resources, Yeungnam University)
Publication Information
Journal of Korean Society of Forest Science / v.99, no.4, 2010 , pp. 546-552 More about this Journal
Abstract
The aim of the study was to assess the cosmeceutical activity of Pyrus ussuriensis leaves and it is possible that can be used as a cosmetic ingredient for application of cosmetic industries. P. ussurensis leaf was extracted with various solvents including water, 70% ethanol and 60% acetone. In the result of DPPH (1,1-diphenyl-2-picryl-hydrazyl) scavenging radical activity, water, ethanol and acetone extract of P. ussuriensis leaf were higher than 70%, 80% and 85% at 50 ppm concentration, respectively. Xanthine oxidase inhibition activity and superoxide dismutase (SOD)-like activity by P. ussuriensis extract were higher than 30%. In addition, SODlike activity of all extracts showed tendency of the significant increase with the increase of concentration. In the anti-inflammatory test, P. ussuriensis leaf extract inhibited generation of nitric oxide (NO) stimulated by LPS in the macrophage cell line (raw 264.7) after 12 to 24 hours. As above results, P. ussuriensis has a great potential as a cosmeceutical raw material as well as anti-oxidant and anti-inflammatory ability.
Keywords
Pyrus ussuriensis; Anti-oxidative ability; Cosmeceutical raw material;
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