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Skin Whitening and Skin Immune Activities of Different Parts of Acer mono and Acer okamotoanum  

Jeong, Myoung-Hoon (College of Bioscience and Biotechnology, Kangwon National University)
Kim, Seung-Seop (College of Bioscience and Biotechnology, Kangwon National University)
Kim, Ji-Seon (College of Bioscience and Biotechnology, Kangwon National University)
Lee, Hak-Ju (Korea Forest Research Institute)
Chio, Geun-Pyo (Department of Food Processing & Bakery, Gangneung Provincial Univ.)
Lee, Hyeon-Yong (College of Bioscience and Biotechnology, Kangwon National University)
Publication Information
Journal of Korean Society of Forest Science / v.99, no.4, 2010 , pp. 470-478 More about this Journal
Abstract
UV-protection skin whitening and immune activities several parts of Acer mono and Acer okamotoanum were investigated. The bark of both Acer mono and Acer okamotoanum had higher yields than other parts as 2.67% and 2.45%. The cytotoxicity of the extracts were lower than 21.64% against human skin cell(CCD-986sk) line in adding 1.0 mg/mL of the highest concentration. The bark extracts of Acer mono greatly reduced the expression of MMP-1 on UV-irradiated CCD-986sk cells down to as 30%. At 1.0 mg/mL of bark extration of Acer mono, $PGE_2$ expression was also significantly decreased. Generally, the bark extracts of Acer mono and Acer okamotoanum had higher activity than other parts, but, interestingly, wood extract of Acer okamotoanum showed strong inhibition effect on melanin production by Clone-M3 cells as 79.25%. From these results, we could conclude that the bark extract from Acer mono and Acer okamotoanum had skin-whitening activity as well immune enhancement activity.
Keywords
Acer mono; Acer okamotoanum; skin immuno modulating activity; skin whitening activity;
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Times Cited By KSCI : 11  (Citation Analysis)
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