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http://dx.doi.org/10.6109/jkiice.2021.25.2.221

Cell differentiation control device capable of simultaneous stimulation of multi-wavelength LED  

Choe, Se-woon (Department of IT Convergence Engineering, Kumoh National Institute of Technology)
Publication Information
Journal of the Korea Institute of Information and Communication Engineering / v.25, no.2, 2021 , pp. 221-227 More about this Journal
Abstract
Recently, interests in mask-type skin care devices using light-emitting diodes have been increasing and optical stimuli at certain wavelengths have been known to have various therapeutic effects, such as skin whitening, acne treatment, elasticity and wrinkle improvement by controlling the exposure to wavelengths of light and irradiation time. In particular, light sources of different wavelengths are applied in masks for the purpose of suppressing skin aging, inducing cell proliferation, and alleviating skin inflammation. In this paper, we developed a light-emitting diode control system that is actively used in skin regeneration masks using a microcontroller. Optical stimuli with different manners were applied to skin fibroblast cells in a single or complex wavelengths, and then confirmed how they are effective in the cell differentiation. In addition, we found a specific wavelength that has a positive effect on cell proliferation rates, and confirm the effectiveness of cell proliferation by image processing based quantitative analysis.
Keywords
Light-emitting diode; Human fibroblast cells; Cell differentiation; Multi-wavelength optical stimulation;
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1 U. D. Cho, "Designing of Complex Miniature Skin Care System," Journal of Industrial Design, vol. 4, no. 4, pp. 19-29, Dec. 2010.
2 J. H. Ji, "A Study on the Use of Beauty Equipments among Adult Women and Preferences," Journal Of The Korean Society of Design Culture, vol. 24, no. 4, pp. 407- 417, Dec. 2018.   DOI
3 S. J. Kim and Y. W. Lee, "Experimental Study on LED Irradiating Effects on Human Cell with the Change of the Energy and Wavelengths," The Journal of Korean Institute of Information Technology, vol. 14, no. 1, pp. 79-84, Jan. 2016.
4 P. Papageorgiou, A. Katsambas, and A. Chu, "Phototherapy with blue (415 nm) and red (660 nm) light in the treatment of acne vulgaris," British Journal of Dermatology, vol. 142, pp. 973-978, May. 2000.   DOI
5 S. Lee, C. You, and M. Park, "Blue and Red Light Combination LED Phototherapy for Acne Vulgaris in Patients with Skin Phototype IV," Lasers in Surgery and Medicine, vol. 39, pp. 180-188, Feb. 2007.   DOI
6 D. An, M. Kim, and S. Choe, "Optical and ultrasonic stimulation system to control fibroblast cell proliferation," The Transactions of the Korean Institute of Electrical Engineers, vol. 69, no. 12, pp. 1977-1982, Dec. 2020.   DOI
7 J. Ha, M. Kwon, S. Kim, M. Jeong, B. Hwang, and H. Lee, "Enhancement of Skin-Whitening and UV-Protective Effects of Centella asiatica L.Urban by Utrasonification Process," Korean Journal of Medicinal Crop Science, vol. 18, no. 2, pp. 79-85, Apr. 2010.
8 S. Choe and H. Choi, "Suppression technique of HeLa cells proliferation using ultrasonic power amplifiers integrated with a series-diode linearizer," Sensors, vol. 18, no. 12, 4248, Dec. 2018.   DOI
9 S. Lee, C. You, and M. Park, "Blue and Red Light Combination LED Phototherapy for Acne Vulgaris in Patients with Skin Phototype IV," Lasers in Surgery and Medicine, vol. 39, pp. 180-188, Feb. 2007.   DOI
10 S. Choe, K. Park, C. W. Park, J. Ryu, and H. Choi, "Combinational light emitting diode-high frequency focused ultrasound treatment for HeLa cell," Computer Assisted Surgery, vol. 22, no. 1, pp. 79-85, Sep. 2017.   DOI
11 H. Choi and S. Choe, "Acoustic stimulation by shunt-diode pre-linearizer using very high frequency piezoelectric transducer for cancer therapeutics," Sensors, vol. 19, no. 2, 357, Jan. 2019.   DOI
12 K. Cho and S. Choe, "Basic study on proliferation control of cancer cells using combined ultrasound and LED therapeutic module," Journal of the Korea Institute of Information and Communication Engineering, vol. 22, no. 8, pp. 1107-1113, Aug. 2018.   DOI
13 K. Cho, J. Seo, G. Heo, and S. Choe, "An alternative approach to detecting cancer cells by multi-directional fluorescence detection system using cost-effective LED and photodiode," Sensors, vol. 19, no. 10, 2301, May 2019.   DOI
14 H. Choi, J. Ryu, K. Lim, T. Choe, and M. Leem, "Effect of High Frequency and Ultrasound Therapy on Skin pigmentation and Wrinkle," Asian Journal of Beauty and Cosmetology, vol. 6, no. 3, pp. 11-19, Aug. 2008.
15 K. Cho and S. Choe, "Development of low cost module for proliferation control of cancer cells using LED and its therapeutic effects," Journal of the Korea Institute of Infor mation and Communication Engineering, vol. 22, no. 9, pp. 1237-1242, Sep. 2018.
16 H. Choi, S. Choe, and J. Ryu, "A marco lens-based optical system design for phototherapeutic instrumentation," Sensors, vol. 19, no. 24, pp. 5427, Dec. 2019.   DOI
17 S. Choe, D. S. Terman, A. E. Rivers, J. Rivera, R. Lottenberg, and B. S. Sorg, "Drug-loaded sickle cells programmed ex vivo for delayed hemolysis target hypoxic tumor microvessels and augment tumor drug delivery," Journal of Controlled Release, vol. 171, pp. 184-192. Oct. 2014.   DOI
18 H. Choi, J. Ryu, and S. Choe, "A novel therapeutic instrument using an ultrasound light-emitting diode with an adjustable telephoto lens for suppression of tumor cell proliferation," Measurement, vol. 147, pp. 106865, Dec. 2019.   DOI