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http://dx.doi.org/10.6109/jkiice.2018.22.8.1107

Basic study on proliferation control of cancer cells using combined ultrasound and LED therapeutic module  

Cho, Kyung-rae (Department of Medical IT Convergence Engineering, Kumoh National Institute of Technology)
Choe, Se-woon (Department of Medical IT Convergence Engineering, Kumoh National Institute of Technology)
Publication Information
Journal of the Korea Institute of Information and Communication Engineering / v.22, no.8, 2018 , pp. 1107-1113 More about this Journal
Abstract
Ultrasonography and photodynamic therapy have been proposed as useful tools as a treatment for inducing necrosis of cells using reactive oxygen species. Apoptosis is an internal mechanism necessary for cells regardless of damage. Ultrasound has the effect of inducing the apoptosis of these cells, and the frequency of 1 MHz is the most applicable area for medical use. The laser which is generally used in photodynamic therapy has a heat reaction and the treatment is limited. However, as a small light emitting diode is developed, it shows possibility to minimize the equipment and reduce heat reaction. On the other hand, there are relatively few researches on direct effects of light compared with studies using photosensitizers, and the area is also limited. Therefore, in this paper, we have developed a cancer cell proliferation control module using ultrasonic and light emitting diodes, which have relatively few side effects, and quantitatively analyze the effect of the module to propose an optimal suppression technique.
Keywords
Light-Emitting Diode; Cancer therapy; Cell proliferation; Ultrasound; HeLa;
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Times Cited By KSCI : 1  (Citation Analysis)
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