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http://dx.doi.org/10.6109/jkiice.2014.18.8.2017

Efficacy of Gene Transfer and Expression of Novel Recombinant Baculovirus Vector  

Kweon, Tae-Dong (Department of Anesthesiology and Pain Medicine, Yonsei University College of Medicine)
Hong, Seong-Karp (Division of Bio and Health Sciences, Mokwon University)
Publication Information
Journal of the Korea Institute of Information and Communication Engineering / v.18, no.8, 2014 , pp. 2017-2022 More about this Journal
Abstract
Novel baculovirus vector systems recombined with coding genes of polyhedron promoter, vesicular stomatitis virus G (VSVG), polyA, cytomegalovirus (CMV) promoter, enhanced green fluorescent protein (EGFP), and protein transduction domain (PTD) were constructed. These recombinant baculovirus vector systems were applied into human foreskin fibroblast cells and compared the effects of gene transfer and gene expression of these recombinant baculovirus vector systems with control vector system. From this study, it showed that these novel recombinant baculovirus vector systems were superior efficacy to control vector system in view of gene transfer and gene expression.
Keywords
baculovirus; enhanced green fluorescent protein; protein transduction domain; vesicular stomatitis virus G;
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