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http://dx.doi.org/10.6109/jkiice.2011.15.3.747

Classification of Ovarian Cancer Microarray Data based on Intelligent Systems with Marker gene  

Park, Su-Young (조선대학교)
Jung, Chai-Yeoung (조선대학교)
Abstract
Microarray classification typically possesses two striking attributes: (1) classifier design and error estimation are based on remarkably small samples and (2) cross-validation error estimation is employed in the majority of the papers. A Microarray data of ovarian cancer consists of the expressions of thens of thousands of genes, and there is no systematic procedure to analyze this information instantaneously. In this paper, gene markers are selected by ranking genes according to statistics, popular classification rules - linear discriminant analysis, k-nearest-neighbor and decision trees - has been performed comparing classification accuracy of data selecting gene markers and not selecting gene markers. The Result that apply linear classification analysis at Microarray data set including marker gene that are selected using ANOVA method represent the highest classification accuracy of 97.78% and the lowest prediction error estimate.
Keywords
microarray; statistics; gene markers; classification rules;
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