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http://dx.doi.org/10.13048/jkm.21007

A review on the treatment of Herbal Medicine for asymptomatically infected COVID-19 patients  

Jeong, Seonhyung (Department of Korean Medicine, College of Korean Medicine, Woosuk University)
Lee, Kyoungeun (Department of Korean Medicine, College of Korean Medicine, Woosuk University)
Jeong, Minjeong (Department of Pediatrics, College of Korean Medicine, Woosuk University)
Song, Mideok (Kyunghee Oriental Medical Clinic)
Jang, Insoo (Department of Internal Medicine, College of Korean Medicine, Woosuk University)
Publication Information
The Journal of Korean Medicine / v.42, no.1, 2021 , pp. 99-109 More about this Journal
Abstract
Objectives: Objective: The purpose of this study is to investigate the treatment of herbal medicine for patients with COVID-19 asymptomatic infections. Method: In English, search engines such as 'PubMed', 'Science Direct', and 'Cumulative Index to Nursing and Allied Health Literature (CINAHL)' were used. In Chinese, search engines such as 'China National Knowledge Infrastructure (CNKI)' and Wanfang were used. The keywords for the search engines were 'COVID-19', 'asymptomatic infection', 'Korean Medicine', 'traditional Chinese medicine', 'herbal medicine', and etc. Only clinical studies using herbal medicine for patients without fever or respiratory symptoms were selected. We excluded the cases that do not fit the research topic. Results: A total of 5 studies were finally selected. Among them, four of them used integrated herbal medicine and Western medicine, and one of the studies treated exclusively for herbal medicine. There were a total of seven prescriptions for herbal medicine used in the study. Outcome variables were used as following: lab test, nucleic acid conversion time, hospitalization period, chest CT, and etc. In the RCT study, herbal medicine and Western medicine decreased nucleic acid conversion time, average hospitalization time compared to the control group, but it was not statistically significant. No other adverse reactions were reported in all studies. Conclusion: According to the results, integrated herbal medicine and Western medicine might be an effective treatment for patients with COVID-19 asymptomatic infection reducing hospitalization period, time of nucleic acid turning negative. No severe adverse effects were reported. However, it is thought that better-designed research will be needed in the future.
Keywords
COVID-19; asymptomatic infection; herbal medicine; Korean medicine;
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