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http://dx.doi.org/10.22246/jikm.2022.43.3.451

A Case Report of Chemotherapy-Induced Peripheral Neuropathy Treated with Modified Guibi-tang  

Park, Su Bin (Dept. of Korean Internal Medicine, Kyung Hee University Hospital at Gangdong)
Yoon, Jee-Hyun (Dept. of Korean Internal Medicine, Kyung Hee University Hospital at Gangdong)
Kim, Eun Hye (Dept. of Korean Internal Medicine, Kyung Hee University Hospital at Gangdong)
Yoon, Seong Woo (Dept. of Korean Internal Medicine, Kyung Hee University Hospital at Gangdong)
Publication Information
The Journal of Internal Korean Medicine / v.43, no.3, 2022 , pp. 451-459 More about this Journal
Abstract
Objective: The purpose of this study was to report the effectiveness of modified Guibi-tang in a patient suffering from chemotherapy-induced peripheral neuropathy (CIPN). Methods: A 54-year-old Korean female patient diagnosed with recurrent ovarian cancer had CIPN with other symptoms, such as anorexia, dyspepsia, insomnia, etc. She was diagnosed with Simbiyangheo and hence treated with a modified Guibi-tang. Neuropathic symptoms were assessed using a numerical rating scale (NRS) and a sensory score. Quality of life was assessed using the Functional Assessment of Cancer Therapy/Gynecologic Oncology Group Neurotoxicity (FACT/GOG-Ntx). Results: After 14 days of treatment, the patients showed a decrease in NRS for bilateral limb pain and improvement in other symptoms, such as general weakness, insomnia, dizziness, and headache. Quality of life also increased. Conclusion: Modified Guibi-tang may be considered an optional treatment for CIPN if the patient is diagnosed with Simbiyangheo. Further studies are needed to confirm this finding.
Keywords
chemotherapy-induced peripheral neuropathy; Guibi-tang; cancer; herbal medicine; case report;
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Times Cited By KSCI : 5  (Citation Analysis)
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