A Case Report of Hypopharyngeal Cancer Improved with Chemotherapy and Korean Medicine Therapy
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Moon, Hyang-ran
(Jangdeuk Korean Medicine Hospital)
Jo, On-you (Jangdeuk Korean Medicine Hospital) Jeong, Seong-heon (Jangdeuk Korean Medicine Hospital) Yoon, Min-ji (Jangdeuk Korean Medicine Hospital) Jang, Kwon-jun (Jangdeuk Korean Medicine Hospital) Yang, Jung-min (Jangdeuk Korean Medicine Hospital) Lee, Ji-yoon (Jangdeuk Korean Medicine Hospital) Hwang, Woo-seok (Jangdeuk Korean Medicine Hospital) Shin, Kwang-soon (Jangdeuk Korean Medicine Hospital) |
1 | Hsieh CH, Lin CY, Hsu CL, Fan KH, Huang SF, Liao CT, et al. Incorporation of Astragalus polysaccharides injection during concurrent chemoradiotherapy in advanced pharyngeal or laryngeal squamous cell carcinoma: preliminary experience of a phase II double-blind, randomized trial. J Cancer Res Clin Oncol 2020;146(1):33-41. DOI |
2 | Kim EH, Kim GU, Park HG, Lee BU. A Investigation on the Fumigation Therapy and Aroma Therapy in 「Oedaebiyo」. The Journal of Korean Medical Classics 2005;18(3):116-25. |
3 | Persky MS, Daly JF. Combined therapy vs curative radiation in the treatment of pyriform sinus carcinoma. Otolaryngol Head Neck Surg 1981;89(1):87-91. DOI |
4 | Xiao D, Peng C, Chen H, Xiao H, Li H, Efficacy of Tongguan Liyan Decoction on pharyngeal cancer-induced dysphagia. All Life 2021;14(1):159-71. DOI |
5 | Eisenhauer EA, Therasse P, Bogaerts J, Schwartz LH, Sargent D, Ford R, et al. New response evaluation criteria in solid tumours: revised RECIST guideline (version 1.1). Eur J Cancer 2009;45(2):228-47. DOI |
6 | National Comprehensive Cancer Network. NCCN Guidelines for Patients-Head and Neck Cancers. 2021. |
7 | Tae K, Shin KS, Kim TH, Shin JH, Jeong JH, Ahn TH, et al. The treatment outcome of hypopharynx cancer: surgery versus organ preservation therapy. Korean J Otorhinolaryngol-Head Neck Surg 2009;52(8):688-94. DOI |
8 | Posner MR, Hershock DM, Blajman CR, Mickiewicz E, Winquist E, Gorbounova V, et al. Cisplatin and fluorouracil alone or with docetaxel in head and neck cancer. N Engl J Med 2007;357(17):1705-15. DOI |
9 | Pingree TF, Davis RK, Reichman O, Derrick L. Treatment of hypopharyngeal carcinoma: a 10-year review of 1,362 cases. Laryngoscope 1987;97(8 Pt 1):901-4. |
10 | Huang CC, Ho TJ, Ho HY, Chen PY, Tu CH, Huang YC, et al. Acupuncture Relieved Chemotherapy-Induced Peripheral Neuropathy in Patients with Breast Cancer: A Pilot Randomized Sham-Controlled Trial. J Clin Med 2021;10(16):3694. DOI |
11 | Lin HC, Lin CL, Huang WY, Shangkuan WC, Kang BH, Chu YH, et al. The use of adjunctive traditional Chinese medicine therapy and survival outcome in patients with head and neck cancer: a nationwide population-based cohort study. QJM 2015;108(12):959-65. DOI |
12 | Kang PG, Park DI, Choi WC, Jeon JC. Effects of Several Medicine Herb Prescriptions on Lung Carcinoma Cells. Journal of Korean Oriental Internal Medicine 2000;21(4):621-31. |
13 | Korea Central Cancer Registry, National Cancer Center. Annual report of cancer statistics in Korea in 2018, Ministry of Health and Welfare. 2020. |
14 | Ko YC, Lee SE, Park BM, Ro SS, Geum CN, Lee SH, et al. Study on Anticancer Mechanism of Gilkyeung-Tang in Lung Cancer Cells. The Journal of the Korea institute of oriental medical informatics 2003;9(2):94-113. |
15 | Song BK. Effects of Herbs on the Immune Responses. Korean Oriental Medical Society 1997;18(2):43-57. |
16 | Park SE, Yoo HS, Jin CY, Hong SH, Lee YW, Kim BW, et al. Induction of apoptosis and inhibition of telomerase activity in human lung carcinoma cells by the water extract of Cordyceps militaris. Food Chem Toxicol 2009;47(7):1667-75. DOI |
17 | Zhang DY, Wu J, Ye F, Xue L, Jiang S, Yi J, et al. Inhibition of cancer cell proliferation and prostaglandin E2 synthesis by Scutellaria baicalensis. Cancer Res 2003;63(14):4037-43. |
18 | Han IS, Kim BW. The Effects of Astragali Radix on Cyclophosphamide-induced Leukocytopenia. J Int Korean Med 2006;27(3):579-88. |
19 | Spaulding MB, Kahn A, Sundquist N, Lore JMJr. Preoperative chemotherapy for hypopharyngeal carcinoma. Laryngoscope 1983;93(3):346-9. |
20 | de Graeff A, de Leeuw JR, Ros WJ, Hordijk GJ, Blijham GH, Winnubst JA. Long-term quality of life of patients with head and neck cancer. Laryngoscope 2000;110(1):98-106. DOI |
21 | Garneau JC, Bakst RL, Miles BA. Hypopharyngeal cancer: A state of the art review. Oral Oncol 2018;86:244-50. DOI |
22 | Ben-Arie E, Wei TH, Chen HC, Huang TC, Ho WC, Chang CM, et al. Digestion-Specific Acupuncture Effect on Feeding Intolerance in Critically Ill Post-Operative Oral and Hypopharyngeal Cancer Patients: A Single-Blind Randomized Control Trial. Nutrients 2021;13(6):2110. DOI |
23 | National Cancer Institute. Common Terminology Criteria for Adverse Events(CTCAE) v.5.0. 2017. Available from : URL : http://ctep.cancer.gov/protocolDevelopment/electronic_applications/CTC.htm. Accessed October 26, 2021. |
24 | 許浚. 東醫寶鑑. 서울: 법인문화사; 1999, p. 1433. |
25 | Avincsal MO, Shinomiya H, Teshima M, Kubo M, Otsuki N, Kyota N, et al. Impact of alcohol dehydrogenase-aldehyde dehydrogenase polymorphism on clinical outcome in patients with hypopharyngeal cancer. Head Neck 2018;40(4):770-7. DOI |
26 | Catimel G, Verweij J, Mattijssen V, Hanauske A, Piccart M, Wanders J, Franklin H, Le Bail N, Clavel M, Kaye SB. Docetaxel (Taxotere): an active drug for the treatment of patients with advanced squamous cell carcinoma of the head and neck. EORTC Early Clinical Trials Group. Ann Oncol 1994;5(6):533-7. |
27 | Vermorken JB, Remenar E, van Herpen C, Gorlia T, Mesia R, Degardin M, et al, Lefebvre JL; EORTC 24971/TAX 323 Study Group. Cisplatin, fluorouracil, and docetaxel in unresectable head and neck cancer. N Engl J Med 2007;357(17):1695-704. DOI |
28 | Lee JH, Chung HJ, Chung SG, Rhee HK. Experimental studies on antitumor effects and immune responses of Gylkyungtang and Gylkyungtanggamibang. Kyung Hee Unicersity Oriental Medical Journal 1998;21(1):225-50. |
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