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http://dx.doi.org/10.22246/jikm.2021.42.6.1349

Effectiveness of Additional Administration of a Banha-sasim-tang Formulation to Patients with Gastrointestinal Symptoms (KCD K-code) Not Improved by Western Medicines: A Retrospective Chart Review  

Kim, Cheol-hyun (Dept. of Korean Internal Medicine, Wonkwang University Gwangju Medical Center)
Kim, Kwangho (Dept. of Korean Internal Medicine, Wonkwang University Gwangju Medical Center)
Lee, Young-ung (Dept. of Korean Internal Medicine, Wonkwang University Gwangju Medical Center)
Kang, Sunny (Dept. of Korean Internal Medicine, Wonkwang University Gwangju Medical Center)
Kang, Geonhui (Dept. of Internal Medicine and Neuroscience, College of Korean Medicine, Wonkwang University)
Publication Information
The Journal of Internal Korean Medicine / v.42, no.6, 2021 , pp. 1349-1355 More about this Journal
Abstract
Objectives: The aim of this study was to evaluate the effectiveness of additional administration of Banha-sasim-tang formulation to patients with gastrointestinal symptoms that did not improve with Western medicines. Methods: The patients who met the inclusion and exclusion criteria were analyzed retrospectively. A paired t-test was performed on the Nepean Dyspepsia Index-Korean version (NDI-K) scores before and after administering the Banha-sasim-tang formulation. Results: A total of 27 subjects were included. The mean duration of taking the Banha-sasim-tang formulation was 15.6±3.1 days. The most commonly used Western medicine before taking the Banha-sasim-tang formulation was rebamipide. The means of the NDI-K score were 57.4±21.8 before administering Banha-sasim-tang formulation and 34.9±16.5 after administration, and the difference was statistically significant (p<0.0001). No serious side effects were encountered while taking the Banha-sasim-tang formulation. Conclusions: For patients whose gastrointestinal symptoms do not improve with Western medicines, additional administration of Banha-sasim-tang formulation may be an option. However, as this study is a retrospective chart review, prospective, large-scale, double-blind studies are needed in the future.
Keywords
Banha-sasim-tang; herbal medicine formulation; Nepean Dyspepsia Index-Korean version (NDI-K); gastrointestinal symptoms; retrospective chart review;
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