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http://dx.doi.org/10.22246/jikm.2021.42.5.853

A Case Report on Korean Medical Treatment for Induced Remission of Pediatric Crohn's Disease  

Lee, Hyun-Jin (Dept. of Clinical Korean Medicine, Graduate School, Kyung Hee University)
Lee, Hanul (Dept. of Digestive Diseases, Kyung Hee University Korean Medicine Hospital)
Jeong, Hae In (Dept. of Clinical Korean Medicine, Graduate School, Kyung Hee University)
Cho, Yun-jae (Dept. of Clinical Korean Medicine, Graduate School, Kyung Hee University)
Keum, Chang-Yul (Dept. of Clinical Korean Medicine, Graduate School, Kyung Hee University)
Han, Aram (Dept. of Clinical Korean Medicine, Graduate School, Kyung Hee University)
Ha, Na-yeon (Dept. of Digestive Diseases, Kyung Hee University Korean Medicine Hospital)
Kim, Jinsung (Dept. of Clinical Korean Medicine, Graduate School, Kyung Hee University)
Publication Information
The Journal of Internal Korean Medicine / v.42, no.5, 2021 , pp. 853-862 More about this Journal
Abstract
Objectives: This case study examined the effectiveness of Korean medical treatment for pediatric Crohn's disease. Methods: A 15-year-old female Korean patient with Crohn's disease received acupuncture, electroacupuncture, herbal medicine, moxibustion, and aromatherapy treatment for 1 month in a hospital. Results: Decreases in the Pediatric Crohn's Disease Activity Index score (from 22.5 to 7.5) and the size of two abscesses (from 39.97 mm to 33.36 mm, and from 28.14 mm to 18.71 mm) according to an abdominal CT were observed following treatment. Nausea and vomiting disappeared, stool condition improved, and weight increased (from 30 kg to 33 kg) following treatment. Nausea and vomiting disappeared, stool condition improved, and weight increased (from 30 kg to 33 kg) following treatment. Conclusion: It would be worth examining the long-term effectiveness of Korean medical treatment for pediatric Crohn's disease.
Keywords
pediatric Crohn's disease; herbal medicine; electroacupuncture; moxibustion; Korean medical treatment;
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1 Kong KA. Efficacy of acustimulation for post-operative nausea and vomiting : A systematic review of randomized clinical trials. Korean Academic Society of Womens Health 2012;13(1):39-54.
2 Wu HG, Liu HR, Tan LY, Gong YJ, Shi Y, Zhao TP, et al. Electroacupuncture and moxibustion promote neutrophil apoptosis and improve ulcerative colitis in rats. Dig Dis Sci 2007;52(2):379-84.   DOI
3 Wu HG, Zhou LB, Pan YY, Huang C, Chen HP, Shi Z, et al. Study of the mechanisms of acupuncture and moxibustion treatment for ulcerative colitis rats in view of the gene expression of cytokines. World J Gastroenterol 1999;5(6):515-7.   DOI
4 Shang HX, Wang AQ, Bao CH, Wu HG, Chen WF, Wu LY, et al. Moxibustion combined with acupuncture increases tight junction protein expression in Crohn's disease patients. World J Gastroenterol 2015;21(16):4986-96.   DOI
5 Pigneur B, Seksik P, Viola S, Viala J, Beaugerie L, Girardet JP, et al. Natural history of Crohn's disease: comparison between childhood- and adult-onset disease. Inflamm Bowel Dis 2010;16(6):953-61.   DOI
6 Druyan ME, Compher C, Boullata JI, Braunschweig CL, George DE, Simpser E, et al. Clinical guidelines for the use of parenteral and enteral nutrition in adult and pediatric patients: applying the GRADE system to development of A.S.P.E.N. clinical guidelines. J Parenter Enteral Nutr 2012;36(1):77-80.   DOI
7 Jones VA. Comparison of total parenteral nutrition and elemental diet in induction of remission of Crohn's disease. Long-term maintenance of remission by personalized food exclusion diets. Dig Dis Sci 1987;32(12 Suppl):100S-107S.   DOI
8 Park JJ, Yang SK, Ye BD, Kim JW, Park DI, Yoon H, et al. Second Korean Guidelines for the Management of Crohn's Disease. Korean J Gastroenterol 2017;69(1):29-54.   DOI
9 Dignass A, Van Assche G, Lindsay JO, Lemann M, Soderholm J, Colombel JF, et al. The second European evidence-based Consensus on the diagnosis and management of Crohn's disease: Current management. J Crohns Colitis 2010;4(1):28-62.   DOI
10 Kim HJ, Hann HJ, Hong SN, Kim KH, Ahn IM, Song JY, et al. Incidence and natural course of inflammatory bowel disease in Korea, 2006-2012: a nationwide population-based study. Inflamm Bowel Dis 2015;21(3):623-30.   DOI
11 Ashton JJ, Gavin J, Beattie RM. Exclusive enteral nutrition in Crohn's disease: Evidence and practicalities. Clin Nutr 2019;38(1):80-9.   DOI
12 Lee JH. Inflammatory Bowel Disease in Pediatric Age. Korean J Pediatr Gastroenterol Nutr 2011;14(1):S34-41.   DOI
13 Cosgrove M, Al-Atia RF, Jenkins HR. The epidemiology of paediatric inflammatory bowel disease. Arch Dis Child 1996;74(5):460-1.   DOI
14 Ko EY, Park KW, Kim HY, Jung SE, Kim WK, Min HS. Outcome of Operation in Crohn's Disease in Children. Journal of the Korean Association of Pediatric Surgeons 2005;11(2):131-40.   DOI
15 Van Limbergen J, Russell RK, Drummond HE, Aldhous MC, Round NK, Nimmo ER, et al. Definition of phenotypic characteristics of childhood-onset inflammatory bowel disease. Gastroenterology 2008;135(4):1114-22.   DOI
16 이수찬. 반하사심탕 물 추출물의 항염증작용에 관한 연구. 국내박사학위논문 원광대학교. 2011.
17 Kim HS. Diagnosis and treatment of Crohn's disease. J Korean Med Assoc 2017;60(6):484-90.   DOI
18 Ho TY, Lo HY, Chao DC, Li CC, Liu JJ, Lin C, et al. Electroacupuncture improves trinitrobenzene sulfonic Acid-induced colitis, evaluated by transcriptomic study. Evid Based Complement Alternat Med 2014;2014:942196.
19 Dundee JW. Belfast experience with P6 acupuncture antiemesis. Ulster Med J 1990;59(1):63-70.
20 Zhao C, Bao C, Li J, Zhu Y, Wang S, Yang L, et al. Moxibustion and Acupuncture Ameliorate Crohn's Disease by Regulating the Balance between Th17 and Treg Cells in the Intestinal Mucosa. Evid Based Complement Alternat Med 2015;2015:938054.
21 Bao CH, Zhao JM, Liu HR, Lu Y, Zhu YF, Shi Y, et al. Randomized controlled trial: moxibustion and acupuncture for the treatment of Crohn's disease. World J Gastroenterol 2014;20(31):11000-11.   DOI
22 Yan J, Zhang H, Chen CT, Yang QY, Liao WF, Chen PG. Effects of electroacupuncture at Shangjuxu (ST 37) on interleukin-1beta and interleukin-4 in the ulcerative colitis model rats. J Tradit Chin Med 2009;29(1):60-3.   DOI