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http://dx.doi.org/10.22246/jikm.2020.41.6.1015

Validity Study of the Systemic Exertion Intolerance Disease Questionnaire (SEID-Q27) for Chronic Fatigue Syndrome (CFS) Diagnosis  

Lim, Eun-jin (Institute of Bioscience and Integrative Medicine, Dept. of Oriental Medicine College, Daejeon University)
Son, Chang-gue (Institute of Bioscience and Integrative Medicine, Dept. of Oriental Medicine College, Daejeon University)
Jang, Eun-su (Institute of Bioscience and Integrative Medicine, Dept. of Oriental Medicine College, Daejeon University)
Publication Information
The Journal of Internal Korean Medicine / v.41, no.6, 2020 , pp. 1015-1029 More about this Journal
Abstract
Purpose: This study assessed the validity of a questionnaire (SEID-Q27) for diagnosis of chronic fatigue syndrome (CFS), designed based on the systematic exertion intolerance disorder (SEID) criteria. Methods: Two groups of participants were recruited: 1. a non-CFS control group: adult university personnel with a Chalder fatigue scale (CFQ) score ≥15, and 2. a CFS patient group: patients from an online CFS community diagnosed with CFS (diagnostic code of G93.3) with the symptoms present. The survey ran from September to October, 2020. The validity of the questionnaire was investigated by factor analysis and receiver operator characteristic (ROC) analysis. Results: Among the 35 adults surveyed, 30 (86%) participants had CFQ scores ≥15 (15 males and 15 females) and 5 (14%) had a CFS diagnosis (2 males and 3 females). The total mean score was significantly different between the two groups (CFS: 6.8±2.2 vs. control: 4.4±2.4, p<0.05). The area under the curve (AUC) was 0.827. With a cut-off point 62, the sensitivity was 60%, specificity 97%, and the discriminant ability of the survey was 79%. Conclusions: The SEID -Q27 appears to be a useful instrument for the diagnosis of CFS using SEID criteria. However, further large-scale studies are needed with greater numbers of participants.
Keywords
chronic fatigue syndrome; myalgic encephalitis; systemic exertion intolerance disease; diagnostic tool; questionnaire validity;
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