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http://dx.doi.org/10.22246/jikm.2019.40.6.1145

Effect of Herbal Medicine on Liver Function in Korean Medical Hospital Inpatients: A Retrospective Chart Review  

Seo, Hyung-bum (Dept. of Korean Internal Medicine, School of Korean Medicine, Pusan National University)
Seo, Hee-jeong (Dept. of Korean Internal Medicine, School of Korean Medicine, Pusan National University)
Shim, So-hyun (Dept. of Korean Internal Medicine, School of Korean Medicine, Pusan National University)
Lee, Chan (Dept. of Korean Internal Medicine, School of Korean Medicine, Pusan National University)
Cho, Im- hak (Dept. of Korean Internal Medicine, School of Korean Medicine, Pusan National University)
Han, Chang-woo (Dept. of Korean Internal Medicine, School of Korean Medicine, Pusan National University)
Kim, So-yeon (Dept. of Korean Internal Medicine, School of Korean Medicine, Pusan National University)
Choi, Jun-yong (Dept. of Korean Internal Medicine, School of Korean Medicine, Pusan National University)
Park, Seong-ha (Dept. of Korean Internal Medicine, School of Korean Medicine, Pusan National University)
Yun, Young-ju (Dept. of Korean Internal Medicine, School of Korean Medicine, Pusan National University)
Hong, Jin-woo (Dept. of Korean Internal Medicine, School of Korean Medicine, Pusan National University)
Kwon, Jung-nam (Dept. of Korean Internal Medicine, School of Korean Medicine, Pusan National University)
Lee, In (Dept. of Korean Internal Medicine, School of Korean Medicine, Pusan National University)
Publication Information
The Journal of Internal Korean Medicine / v.40, no.6, 2019 , pp. 1145-1151 More about this Journal
Abstract
Objectives: The purpose of this study was to investigate liver function test results in admitted patients before and after herbal treatment. Methods: 54 subjects admitted to hospital had liver function tests (aspartate aminotransferase, alanine amino transferase, alkaline phosphatase, total bilirubin) before and after herbal treatment from 1 March 2017 to 30 June 2019. Results: Aspartate aminotransferase, alanine aminotransferase, and alkaline phosphatase were not significantly changed (p>0.05). On admission, 11 patients had abnormal liver function, while seven patients had abnormal results in alkaline phosphatase upon discharge. Three of the seven were normal when they were hospitalized. Conclusions: This study suggests that herbal treatment may have no effect on liver injury.
Keywords
herbal medicine; liver function; drug-induced liver injury;
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Times Cited By KSCI : 1  (Citation Analysis)
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