Browse > Article
http://dx.doi.org/10.22246/jikm.2019.40.6.1015

A Retrospective Chart Review of the Clinical Use of Euphorbia kansui Radix, Melonis Calyx  

Kim, Dong-hyun (Dept. of Internal Medicine, College of Korean Medicine, Kyung Hee University)
Noh, Ji-won (Dept. of Internal Medicine, College of Korean Medicine, Kyung Hee University)
Jeong, Su-min (Dept. of Internal Medicine, College of Korean Medicine, Kyung Hee University)
Ahn, Se-young (Dept. of Internal Medicine, College of Korean Medicine, Kyung Hee University)
Ahn, Young-min (Dept. of Internal Medicine, College of Korean Medicine, Kyung Hee University)
Lee, Byung-cheol (Dept. of Internal Medicine, College of Korean Medicine, Kyung Hee University)
Yoo, Jung-hwa (Dept. of Internal Medicine, College of Korean Medicine, Kyung Hee University)
Publication Information
The Journal of Internal Korean Medicine / v.40, no.6, 2019 , pp. 1015-1025 More about this Journal
Abstract
Objectives: There have been many studies reporting the clinical value of Euphorbia kansui Radix or Melonis Calyx, but few systematic studies of the changes that may occur after taking such herbal medication. This study aimed to investigate the characteristics of the patient group, possible changes in blood test and InBody test results, and to discover the current state and future direction of clinical use of Euphorbia kansui Radix or Melonis Calyx. Methods: This study investigated patients who were hospitalized at Kyung-Hee University Korean Medicine Hospital for at least two days from 1 March 2016 to 1 March 2019, specifically evaluating patients aged 19 and over who underwent blood tests, including an electrolyte test and an InBody test before and after taking Euphorbia kansui Radix or Melonis Calyx. Results: Among a total of 134 patients, 72 patients (53.7%) were treated with Euphorbia kansui Radix and 62 patients (46.3%) were treated with Melonis Calyx, in the context of previously diagnosed abnormal weight gain. Laboratory findings were that Na and K levels were significantly reduced in both groups. In an InBody test, body mass index (BMI), intracellular water, extracellular water, protein, mineral, and skeletal muscle were significantly reduced in both groups. Conclusions: From these results, we suggest that, although Euphorbia kansui Radix and Melonis Calyx may not induce serious adverse effects, attention should be paid to the electrolyte level with the use of these treatments. In terms of syndrome differentiation, more clinical uses will be available in the future.
Keywords
Euphorbia kansui radix; Melonis Calyx; syndrome differentiation; traditional chinese medicine; inbody test;
Citations & Related Records
Times Cited By KSCI : 13  (Citation Analysis)
연도 인용수 순위
1 Kang JY, Lee SH, Lee SK, Hong HJ, Lee CW, Cho HW. A Case Report of Trigeminal Neuralgia Treated with Melonis Calyx Vomiting Therapy. J Korean Med Ophthalmol Otolaryngol Dermatol 2017;30(3):231-8.   DOI
2 Na HY, Yoo JH, Lee DE, Ahn SY, Lee BC, Ahn YM. A Case of Suppression of Supragastric Belching Using Korean Medical Treatment with Melonis Calyx Vomiting Therapy. J Int Korean Med 2016;37(5):863-9.   DOI
3 Lee CW, Kang JY, Lee SH, Kim CH. A Case Report of Tinnitus with Sudden Sensorineural Hearing Loss Treated with Melonis Calyx Vomiting Therapy. J Korean Med Ophthalmol Otolaryngol Dermatol 2015;28(4):186-95.   DOI
4 Lee SH, Lee SK, Hong HJ, Lee CW, Jang YW. A Case Report of Cholinergic Urticaria Patient Using Oriental Medical Treatment with Melonis Calyx Vomiting Therapy. J Korean Med Ophthalmol Otolaryngol Dermatol 2017;30(3):220-30.   DOI
5 Kim TT, Lee CW, Kang JY, Kim CH. Two Cases of Atypical Facial Pain Using Orental Medical Treatment with Melonis Calyx Vomiting Therapy. J Korean Med Ophthalmol Otolaryngol Dermatol 2014;27(3):189-99.   DOI
6 Kim JS, Oh HW, Lee JH, Koh BH, Lee EJ. 3 Case Reports of Tension-type Headache Taeeumin patients using Melonis Pedicus. J Sasang Constitut Med 2014;26(4):409-21.   DOI
7 Lee SW, Kwon OJ, Na HY, Ahn YM, Lee BC, Ahn SY. Retrospective Study for Safety of Xie-xia Fa (瀉下法) by Euphorbia kansui Radix: Analysis of Clinical Features, Liver and Kidney Functions. J Int Korean Med 2014;35(4):472-82.
8 Lee SW, Seol MH, Na HY, Yoo JH, Ahn YM, Lee BC, et al. Retrospective Study of Safety of Tu Fa (吐法) by Melonis Calyx: Analysis of Clinical Features and Liver and Kidney Functions. J Int Korean Med 2015;36(4):498-506.
9 Sullivan PA, Still CD, Jamieson ST Dixon CB, Irving BA, Andreacci JL. Evaluation of multi-frequency bioelectrical impedance analysis for the assessment of body composition in individuals with obesity. Obes Sci Pract 2019;5(2):141-7.   DOI
10 Ham SH, Jeong HY, Lee SJ, Lim EC. A Case-Report on Taeeumin Patient with Essential Tremor using Melonis Pedicelus. J Sasang Constitut Med 2013;25(3):254-63.   DOI
11 Lee SW, Na HY, Seol MH, Kim M, Lee BC. Euphorbia kansui Attenuates Insulin Resistance in Obese Human Subjects and High-Fat Diet-Induced Obese Mice. Evid Based Complement Alternat Med 2017;2017:1-9.
12 박용길, 김우진, 정현권. 보급형 체성분 분석기 제품화 기술개발에 관한 연구. 한국생산기술연구원. 1999.
13 全昌宣. 肥瘦論. 서울: 와이겔리; 2017, p. 236-7.
14 劉渡舟. 劉渡舟傷寒論講義. 丁彰炫譯. 파주: 물고기숲; 2014, p. 305-9.
15 劉渡舟. 劉渡舟傷寒論講義. 丁彰炫譯. 파주: 물고기숲; 2014, p. 233-4.
16 柯琴. 傷寒論注. 안영민 譯. 서울: 한미의학;2012, p. 125-6.
17 劉渡舟. 丁彰炫譯. 劉渡舟傷寒論講義. 파주: 물고기숲; 2014, p. 357-62.
18 이종대. 새로보는 방약합편 : 활투침선 병증도표 손익본초 한의약서. 서울: 청홍; 2012, p. 629.
19 劉渡舟. 劉渡舟傷寒論講義. 丁彰炫譯. 파주: 물고기숲; 2014, p. 388-92.
20 柯琴. 안영민 譯. 傷寒論注. 서울: 한미의학;2012, p. 219-20.
21 이종대. 새로보는 방약합편 : 활투침선 병증도표 손익본초 한의약서. 서울: 청홍; 2012, p. 660.
22 Chen KJ, Xu H. The integration of traditional chinese medicine and western medicine. European Review 2003;11(2):225-35.   DOI
23 He Y, Lu A, Zha Y, Yan X, Song Y, Zeng S, et al. Correlations between symptoms as assessed in traditional chinese medicine and ACR20 efficacy response; a comparison study in 396 patients with rheumatoid arthritis treated with TCM or Western medicine. J Clin Rheumatol 2007;13(6):317-21.   DOI
24 Ma T, Tan C, Zhang H, Ding W, Li S. Bridging the gap between traditional chinese medicine and systems biology ; the connection of cold syndrome and NEI network. Mol Biosyst 2010;6(4):613-9.   DOI
25 Zhu LC. Importance and relationship of disease differentiation in combination with syndrome differentiation. J Tradit Chin Med 1962;4:15-6.
26 Lu A, Jiang M, Zhang C, An integrative approach of linking traditional chinese medicine pattern classification and biomedicine diagnosis. J Ethnopharmacol 2012;141(2):549-56.   DOI
27 Zhang Q, Wu Z, Feng Y, Shi J. Levels of sexual hormones in relation with syndrome- differentiation of TCM in patients of chronic renal failure. J Tradit Chin Med 1990;10(2):132-5.
28 Zhao LH, Xiao C, Yan XP. Correlation between heat or cold syndrome and cytokine, and laboratory index in women with early rheumatoid arthritis. Acta Universitatis Traditionis Medicalis Sinensis Pharmacologiaeque Shanghai 2006;20:21-4.
29 Lu AP, Zhang SS, Zha QL, Ju DH, Wu H, Jia HW, et al. Correlation between CD4, CD8 cell infiltration in gastric mucosa, Hplicobacter pylori infection and symptoms in patients with chronic gastritis. World J Gastroenterol 2005;11(16):2486-90.   DOI
30 Xie YQ, Wang H, Wu YP, Yin DH, Wang ZS, Huang YH. Association of APOE polymorphisms and insulin resistance with TCM syndromes in type 2 diabetes patients with macroangiopathy. Mol Med Rep 2011;4(6):1219-23.   DOI
31 Kim SJ, Jang YW, Hyung KE, Lee DK, Hyun KH, Park SY, et al. Therapeutic Effects of Methanol Extract from Euphorbia kansui Radix on Imiquimod-Induced Psoriasis. J Immunol 2017;2017:7052560.
32 Li S, Rao XR, Wang SX, Zhang GH, Li XM, Dai XW, et al. Study on the relationship between blood stasis syndrome and clinical pathology in 227 patients with primary glomerular disease. Chin J Integr Med 2009;15(3):170-6   DOI
33 Yan Z, Wang K, Li N. Computerized feature quantification of sublingual veins from color sublingual images. Comput Methods Programs Biomed 2009;93(2):192-205.   DOI
34 Xu L, Meng MQ. Morphology variability analysis of wrist pulse waveform for assesment of arteriosclerosis status. J Med Syst 2010;34(3):331-9.   DOI
35 Ban DJ, Hong SY, Park SS. A Study on Indication and Application of Radix Euphorbiae Kansui. Journal of Sasang constitutional medicine 2009;21(3):17-29.
36 Chai YS, Hu J, Wang XK, Wang YG, Xiao XY, Cheng XL, et al. Euphorbia kansui roots induced-diarrhea in mice correlates with inflammatory response. Chin J Nat Med 2013;11(3):231-9.   DOI
37 Cho HW, Lee JW, Lee SJ, Lim EC, Kim DU. 2 Case Reports of Treatment of Soyangin Patients with Atopic Dermatitis using Oriental Medicine Therapy with Euphorbiae Kansui. Radix (Gam-sui). J Sasang Constitut Med 2015;27(3):333-45.   DOI
38 Nam SH, Kim DH, Choi HM, Kang JH, Hyun MK. A Case Report of Lumbar Spinal Stenosis Improved with Diarrhea-Inducing Treatment by Gamsui-mal and Korean Medicine Treatment. Journal of Korean Medicine Rehabilitation 2017;27(1):67-75.   DOI
39 Zhao ZX, Cai GX, Xie S, Zhou XL, Hu XL. Dressing navel with Euphorbia kansui in combination with taken DuShenTang orally to cure ascites caused by hepatocirrhosis in clinic. J Emerg Tradit Chin Med 2010;19:388-9.   DOI
40 Fan Y, Cai DF, Gu XX, Wang GY, Ma J. Treatment of intestinal obstruction with a large dose of kansui. J Emerg Tradit ChinMed 2005;14:278-9.
41 Lv XS, Zhang Y, Li YX, Tang HH, Li XR, Wu FY. Therapeutic effect of kansui root on patients with severe acute Pancreatitis. Chin J Gen Surg 2004;13:401-4.   DOI
42 Ryu H, Ahn HJ, Lee SB, Park SJ. Case Series of Hwa-Byung Patients with Facial Spasm - by Using Oriental Medical Treatment with Melonis Calyx Vomiting Therapy. J of Oriental Neuropsychiatry 2012;23(4):183-98.   DOI