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http://dx.doi.org/10.22246/jikm.2019.40.4.697

A Case Report of the Traditional Korean Treatment of Female Patients with Both Functional Dyspepsia and Chronic Atrophic Gastritis  

Yoon, Sang-hyub (Dept. of Gastroenterology, College of Korean Medicine, Kyung Hee University)
Publication Information
The Journal of Internal Korean Medicine / v.40, no.4, 2019 , pp. 697-708 More about this Journal
Abstract
Objective: The aim of this study was to introduce gastric dysmotility as a common cause in patients with concurrent functional dyspepsia and chronic atrophic gastritis. Method: Dyspeptic symptoms, the Rydoraku score, gastric motility (electrogastrography, bowel sound analysis), gastric mucosa (gastroendoscopy), and blood and blood chemistry were all evaluated. For the treatment method, Pyengwi-san (solution) and Banwhasashim-tang (extract) were used as herbal drugs. Both ST36 electrical stimulation and simple immersion stimulation of CV11, 12, and 13 in the abdomen were applied. Results: Dyspeptic symptoms including indigestion, headache, and insomnia were all relieved. Gastric myoelectrical activity and gastric pyloric function were additionally improved. The condition of the gastric mucosa was changed from atrophic to erosive. Other side-effects of the treatment were not noted. Conclusion: The traditional Korean treatment showed effectiveness in the relief of dyspeptic symptoms and mucosal improvement of chronic atrophic gastritis. Gastric dysmotility is a common cause of the condition being concurrent with both functional dyspepsia and chronic atrophic gastritis without Helicobacter pylori infection.
Keywords
functional dyspepsia; gastric dysmotility; chronic atrophic gastritis; acupuncture; herbal medicine;
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Times Cited By KSCI : 13  (Citation Analysis)
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1 Friesen C, Singh M, Singh V, Schurman JV. An observational study of headaches in children and adolescents with functional abdominal pain: Relationship to mucosal inflammation and gastrointestinal and somatic symptoms. Medicine 2018;97(30):e11395.   DOI
2 Park YS, Yoon SH. Could Headache be one of Symptoms induced by Gastric Dysmotility in Patients with Functional Dyspepsia?. The Journal of Internal Korean Medicine 2009;30(3):604-11.
3 Han DG, Lee CJ. Headache associated with visceral disorders is "parasympathetic referred pain". Med Hypotheses 2009;73(4):561-3.   DOI
4 Yeom JS, Choi MB, Seo JH, Park JS, Lim JY, Park CH, et al. Relationship between headache and mucosal mast cells in pediatric Helicobacter pylori-negative functional dyspepsia. Cephalalgia 2013;33(5):323-9.   DOI
5 Kim SY, Choung RS, Lee SK, Choe JW, Jung SW, Hyun JJ, et al. Self-reported Sleep Impairment in Functional Dyspepsia and Irritable Bowel Syndrome. J Neurogastroenterol Motil 2018;24(2):280-8.   DOI
6 Vege SS, Locke GR, Weaver AL, Farmer SA, Melton LJ, Talley NJ. Functional gastrointestinal disorders among people with sleep disturbances:a population-based study. Mayo Clin Proc 2004;79(12):1501-6.   DOI
7 Park JK, Huh KC, Shin CM, Lee H, Yoon YH, Song KH, et al. Current Issues in Functional Dyspepsia. Korean J Gastroenterol 2014;64(3):133-41.   DOI
8 Lee BR, Kim WI. Systemic Review of Studies for Traditional Chinese Treatment of Intestinal Metaplasia - Research using CNKI. J Int Korean Med 2018;39(6):1085-104.   DOI
9 Li Z, Zhang H, Wang D, Chen X, Li S. Research progress on mechanism of acupuncture for chronic atrophic gastritis. Zhongguo Zhen Ji 2016;36(10):1117-20.
10 Ko SJ, Park JW, Lee JH, Cho SH, Lee JH, Nam SU, et al. Herbal medicine Yukgunja-tang for functional dyspepsia protocol for a systematic review of randomized controlled trials. Medicine (Baltimore) 2018;97(40):e12555.   DOI
11 Lee KM. Two Cases of Chronic Gastritis Treated with Wihwa Herbal-acupuncture. The J of Acu 2003;20(6):218-25.
12 Navas CM, Patel NK, Lacy BE. Symptomatic Management of Gastroparesis. Gastrointest Endosc Clin N Am 2019;29(1):55-70.   DOI
13 Talley NJ, Walker MM, Holtmann G. Functional dyspepsia. Curr Opin Gastroenterol 2016;32(6):467-73.   DOI
14 Lee HW, Kang SH, Park GE, Lee KH, Hong YS, Lee K, et al. Survey on the Endoscopic Diagnosis of Chronic Gastritis. The Korean Journal of Helicobacter and Upper Gastrointestinal Research 2014;14(3):194-8.   DOI
15 Joonsson KA, Gotthard R, Bodemar G, Brodin U. The clinical relevance of endoscopic and histologic inflammation of gastroduodenal mucosa in dyspepsia of unknown origin. Scand J Gastroenterol 1989;24(4):385-95.   DOI
16 Mitchell RM, Collins JS, Watson RG, Tham TC. Differences in the diagnostic yield of upper gastrointestinal endoscopy in dyspeptic patients receiving proton-pump inhibitors and H2-receptor antagonists. Endoscopy 2002;34(7):524-6.   DOI
17 Guo JF, Bai Y, Li ZS. Diagnostic yield of repeat upper gastrointestinal endoscopy for patients with functional dyspepsia. J Dig Dis 2013;14(11):574-8.   DOI
18 Choi MK. Definition and Epidemiology of Functional Dyspepsia. Korean J Neurogastroenterol Motil 2000;6(2):235-40.
19 Park HK, Kim NY, Lee SW, Park JJ, Kim JI, Lee SY, et al. The distribution of endoscopic gastritis in 23,536 health check-up subjects in Korea. The Korean Journal of Helicobacter and Upper Gastrointestinal Research 2012;12(4):237-43.   DOI
20 Yoon SH. Familial Gastric Dysmotility in Monozygotic Twins with Functional Dyspepsia and Their Mothers and the Effect of Korean Traditional Medicine on Symptoms and Gastric Dysmotility in Twins. J Int Korean Med. 2018;39(4):772-83.   DOI
21 Joo MK, Lim HJ, Joo YS, Kim JY, Kim YJ, Yu KH, et al. Validity and Reliability Assessment of Korean Headache Impact Test-6 (HIT-6). Journal of Oriental Neuropsychiatry 2009;27(1):1-6.   DOI
22 Hui WM, Lam SK. Etiology and management of chronic gastritis. Dig Dis 1989;7(1):51-60.   DOI
23 Kim HK, You JM, Jang SY, Lee JS, Um KH, Kim JS, et al. Association of Skin Sympathetic Tone or Cardiovascular Reactivity on the Fatigue Index in Patients with Functional Dyspepsia. Journal of Korean oriental internal medicine 2005;26(2):390-7.
24 Yoon SH. An association of Kyung-Rak Principle and Autonomic Nerve Theory related with Ryodoraku of Patients with Gastric Dysmotility and Gastric Ulcer. The Journal of Internal Korean Medicine 2010;31(4):837-45.
25 Kim SY, Yoon SH, KimYB, Jung SK. Study of Ryodoraku Parameters for Diagnosing Gastric Dysmotility in Functional Dyspepsia. Journal of Korean oriental internal medicine 2008;29(2):401-12.
26 You JM, Jang SY, Kim HK, Lee JS, Yum KH, Lee SR, et al. Effects of Traditional Korean Medical Therapy on Gastric Myoelectrical Activity in Patient with Functional Dyspepsia. Journal of Korean oriental internal medicine 2005;26(2):360-8.
27 Yoon SH. Postprandial Epigastric Fullness and Pyloric Valve Disturbance in Patients with Functional Dyspepsia; Analysis of Bowel Sounds and Electrogastrography. Journal of Korean oriental internal medicine 2007;28(4):769-78.
28 Jung HK. Treatment in Patients with Gastritis:Symptom vs. Inflammation. the 51st seminar Division of Gastroenterology, Korean Society of Gastrointestinal Endoscopy 2014 A-I:29-32.
29 Szarka LA, Camilleri M. Methods for measurement of gastric motility. Am J Physiol Gastrointest Liver Physiol 2009;296(3):461-75.   DOI
30 Sohn SI, Kim DH, Lee MY, Cho YW. The reliability and validity of the Korean version of the Pittsburgh Sleep Quality Index. Sleep Breath 2012;16(3):803-15.   DOI
31 Takaya Y, Tsunoda S, Itoh M, Oshima H. Studies on analysis of gastric mucosal blood flow by electronic endoscopic image. Especially on atrophic gastritis. Nihon Ika Daigaku Zasshi 1994;61(4):295-305.   DOI
32 Piessevaux H, De Winter B, Louis E, Muls V, De Looze D, Pelckmans P, et al. Dyspeptic symptoms in the general population: a factor and cluster analysis of symptom groupings. Neurogastroenterol Motil 2009;21(4):378-88.   DOI
33 Liu J, Jia L, Lei XG, Jiang SM, Wang SB, Xu M. The clinical-psychological features of functional dyspepsia patients with weight loss: a multi-center study from China. Digestion 2015;91(3):197-201.   DOI
34 Lin YP, Yi SX, Yan J, Chang XR. Effect of acupuncture at Foot-Yangming Meridian on gastric mucosal blood flow, gastric motility and brain-gut peptide. World J Gastroenterol 2007;13(15):2229-33.   DOI
35 Shen HL, Yang SP, Wang KJ, Huang BL, Huang WB, Wu JZ, et al. Evaluation of gastric blood supply in diabetic patients with gastroparesis by contrast-enhanced ultrasound. Br J Radiol 2016;89(1068):20160366.   DOI
36 Wang Y, Yuan SY, Zhang ZY. A study of gastric mucosal blood flow of peptic ulcer, chronic gastritis and gastric carcinoma. Zhonghua Nei Ke Za Zhi 1993;32(4):239-42.
37 Kang HS, Kim JH. Atrophic Gastritis: Pathophysiology and Etiology. The Korean Journal of Helicobacter and Upper Gastrointestinal Research 2013;13(1):1-5.   DOI
38 Yamada S, Tomatsuri N, Kawakami T, Nakatsugawa Y, Nishimura T, Fujii H, et al. Helicobacter pylori Eradication Therapy Ameliorates Latent Digestive Symptoms in Chronic Atrophic Gastritis. Digestion 2018;97(4):333-9.   DOI
39 Hwang YJ, Kim N, Lee HS, Lee JB, Choi YJ, Yoon H, et al. Reversibility of atrophic gastritis and intestinal metaplasia after Helicobacter pylori eradication - a prospective study for up to 10 years. Aliment Pharmacol Ther 2018;47(3):380-90.   DOI
40 Kim SY, Yoon SH. A Selective Effect of Combined Treatment of Electroacupuncture at Zusanli(ST36), Manual Acupuncture, and Pyengwi-san in Function Dyspepsia Patients with Pyloric Valve Disturbance and Hypoactivity of Gastric Vagus Nerve. Journal of Korean oriental internal medicine 2009;30(1):191-9.
41 Kim YS, Yoon SH. Combination Effects of Zusanli(ST36) Electroacupuncture and Manual Acupuncture of other Acupoints on Gastric Vagal Nerve Activity and Pyloric Valve Function in Patients with Functional Dyspepsia. Journal of Korean oriental internal medicine 2008;29(3):621-8.
42 Kim JN, Song HJ, Lim B, Kwon YK, Kim BJ. Modulation of pacemaker potentials by Pyungwi-San in interstitial cells of Cajal from murine small intestine. J Pharmacopuncture 2013;16(1):43-9.   DOI
43 Yoon SH, Ryu BH, Ryu KW, Kim JS. Evaluation for Therapeutic Effectiveness of Banwhasashim-tang in Functional Dyspepsia. Journal of Korean oriental internal medicine 2003;24(2):329-36.
44 Kim JJ, Choi YT, Lim JK, Lee YH. The latest acupuncture. Seoul: Sungbosa; 1979, p. 190-2.
45 Iwa M, Nakade Y, Pappas TN, Takahashi T. Electroacupuncture improves restraint stress-induced delay of gastric emptying via central glutaminergic pathways in conscious rats. Neurosci Lett 2006;15(399):6-10.
46 Park YH, Kim NY. Review of atrophic gastritis and intestinal metaplasia as a premalignant lesion of gastric cancer. J Cancer Prev 2015;20(1):25-40.   DOI
47 Choi MG, Choi KW, Kim NY, Huh C, Yang CH, Jang JG, et al. Functional dyspepsia and subgroups in Korea and short term outcome of therapeutic trial of cisapride; multicenter study. Korean J Neurogastroenterol Motil 1998;4(1):1-12.
48 Carson L, Lewis D, Tsou M, McGuire E, Surran B, Miller C, et al. Abdominal migraine: an under-diagnosed cause of recurrent abdominal pain in children. Headache 2011;51(5):707-12.   DOI