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http://dx.doi.org/10.22246/jikm.2017.38.5.812

A Follow-up Study of Clinical Characteristics of Recurrent Aphthous Stomatitis Patients Treated with Herbal Medicine  

Ha, Na-yeon (Dept. of Clinical Korean Medicine, Graduate School, Kyung Hee University)
Lee, Jae-hyung (Dept. of Clinical Korean Medicine, Graduate School, Kyung Hee University)
Lee, Jung-eun (Dept. of Clinical Korean Medicine, Graduate School, Kyung Hee University)
Nam, Seong-uk (Dept. of Clinical Korean Medicine, Graduate School, Kyung Hee University)
Ko, Whee-hyoung (Dept. of Clinical Korean Medicine, Graduate School, Kyung Hee University)
Hwang, Mi-ni (Dept. of Clinical Korean Medicine, Graduate School, Kyung Hee University)
Kim, Jin-sung (Dept. of Clinical Korean Medicine, Graduate School, Kyung Hee University)
Publication Information
The Journal of Internal Korean Medicine / v.38, no.5, 2017 , pp. 812-819 More about this Journal
Abstract
Objectives: The purpose of this study was to report the long-term efficacy of herbal medicine for treatment of patients with recurrent aphthous stomatitis (RAS). Methods: We reviewed the clinical records of 17 patients with RAS who visited the Oral Diseases Clinic of Kyung Hee University Korean Medicine Hospital from September 1st, 2014 to August 29th, 2017. The patients were treated with herbal medicine for more than 3 consecutive weeks, followed by a telephone survey. We evaluated the clinical characteristics of RAS, and compared the short-term and long-term efficacy of herbal medicine treatment. Results: After treatment with herbal medicine, the clinical characteristics improved in the 17 patients with RAS, especially in terms of the duration and interval of recurrence. Prolonged effects were reported upon the follow-up telephone survey. Conclusion: Herbal medicine treatment may have a long-term effect in patients with RAS.
Keywords
recurrent aphthous stomatitis; RAS; clinical characteristics; herbal medicine; follow-up study;
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1 Yoo JG, Choi KH, Kim YK, Kang SK, Jung SY, Jung JH, et al. The study on the anti-inflammatory effects of phellodendri Cortex, Indigo Naturalis, Alumen, and Chinensis Galla, most frequently used for the external theraphy of Gu-Chang. J Korean Orient Med Ophthalmol & Otolaryngo & Dermatol 2005;18(1):183-98.
2 Lee JK, Lee NH, Ha HK, Lee HY, Jung DY, Choi JY, et al. Analysis of studies on Yukmijihwang-tang for Establishment of Evidence Based Medicine. J Physiol & Pathol Korean Med 2009;23(1):15-26.
3 Rogers RS. 3rd Recurrent aphthous stomatitis: clinical characteristics and associated systemic disorders. Semin Cutan Med Surg 1997;16(4):278-83.   DOI
4 Vincent SD, Lilly GE. Clinical historic, and therapeutic features of aphthous stomatitis. Oral Surg Oral Med Oral Pathol 1992;74:79-86.   DOI
5 Pedersen A, Hornsleth A. Recurrent aphthous ulceration: a possible clinical manifestation of reactivation of varicella zoster or cytomegalovirus infection. J Oral Pathol Med 1993;22:64-8.   DOI
6 Committee of Digestive Diseases, National Korean Medicine College. Gastroenterology. Seoul: Koonja publisher; 2009, p. 310.
7 Liu C, Zhou Z, Liu G, Wang Q, Chen J, Wang L, et al. Efficacy and safety of dexamethasone ointment on recurrent aphthous ulceration. Am J Med 2012;125(3):292-301.   DOI
8 Han IS, Kim CJ. Studies on the Activities of Peritoneal Macrophages Induced by Yookmijihwangtang, Palmijihwangtang and Gamijihwangtang. J Korea Inst of Orient Med 1997;6(1):331-47.
9 Jeon JO, Jeong HW. Experimental Effect of Yukmi-jihwang-Tang on the T-lymphocytes and Macrophages. Korean J Orient Int Med 2000;21(2):243-50.
10 Bagan JV, Sanchis JM, Milian MA, Penarrocha M, Silvestre FJ. Recurrent aphthous stomatitis. A study of the clinical characteristics of lesions in 93 cases. J Oral Pathol Med 1991;20:395-7.   DOI
11 Kim JY, Kim JS, Son JH, Seon JK, Kang K, Jang SW, et al. Efficacy of Gamiyukmijihwang-tang on Recurrent Aphthous Stomatitis. Korean J Orient Int Med 2012;33(2):231-42.
12 Han SW, Hong SP, Kim JM, Choi NS, Hong EK, Oh HJ. Prevalence and clinical characteristics of recurrent aphthous stomatitis involving Korean dental profession population. J Korean Dent Assoc 2001;39(1):62-70.
13 Axell T, Henricsson V. The occurrence of recurrent aphthous ulcers in an adult Swedish population. Acta Odontol Scand 1985;43:121-5.   DOI
14 Porter SR, Scully C, Pedersen A. Recurrent aphthous stomatitis. Crit Rev Oral Biol Med 1998;9(3):306-21.   DOI
15 Akintoye SO, Greenberg MS. Recurrent aphthous stomatitis. Dent Clin North Am 2014;58(2):281-97.   DOI
16 Yang YG. Huangdi Neijing Suwen interpretation. Taipei: Taeryeongukpung publisher; 1976, p. 51, 538, 562.
17 Heo J. Dongui Bogam. Seoul: Namsandang; 1994, p. 241-54.
18 Lee Ch. Yixuerumen. Seoul: Namsandang; 1988. p. 1442-4.