Browse > Article
http://dx.doi.org/10.22246/jikm.2017.38.5.806

A Case Report of a Patient with Chemotherapy-induced Leukopenia Treated with Acupuncture  

Choi, Jin-yong (Dept. of Internal Medicine, Korean Medicine Hospital of Pusan National University)
Cho, Jae-hyun (Dept. of Internal Medicine, Korean Medicine Hospital of Pusan National University)
Bae, Go-eun (Dept. of Internal Medicine, Korean Medicine Hospital of Pusan National University)
Shim, So-hyun (Dept. of Internal Medicine, Korean Medicine Hospital of Pusan National University)
Seo, Hee-jeong (Dept. of Internal Medicine, Korean Medicine Hospital of Pusan National University)
Choi, Jun-yong (Dept. of Internal Medicine, Korean Medicine Hospital of Pusan National University)
Kwon, Jung-nam (Dept. of Internal Medicine, Korean Medicine Hospital of Pusan National University)
Lee, In (Dept. of Internal Medicine, Korean Medicine Hospital of Pusan National University)
Hong, Jin-woo (Dept. of Internal Medicine, Korean Medicine Hospital of Pusan National University)
Yun, Young-ju (Dept. of Internal Medicine, Korean Medicine Hospital of Pusan National University)
Park, Seong-ha (Dept. of Internal Medicine, Korean Medicine Hospital of Pusan National University)
Kim, So-yeon (Dept. of Internal Medicine, Korean Medicine Hospital of Pusan National University)
Han, Chang-woo (Dept. of Internal Medicine, Korean Medicine Hospital of Pusan National University)
Publication Information
The Journal of Internal Korean Medicine / v.38, no.5, 2017 , pp. 806-811 More about this Journal
Abstract
Leukopenia is a commonly encountered adverse event experienced by cancer patients. It can cause serious infections and delays in chemotherapy. We describe a case of leukopenia induced by colon cancer chemotherapy. After acupuncture treatment, the patient showed improvement in the leukopenia and completed the scheduled chemotherapy without delay or additional administration of granulocyte colony-stimulating factor (G-CSF). Therefore, acupuncture may have a substantial benefit for treatment of leukopenia in this patient.
Keywords
chemotherapy; leukopenia; neutropenia; acupuncture;
Citations & Related Records
Times Cited By KSCI : 1  (Citation Analysis)
연도 인용수 순위
1 Aapro MS, Bohlius J, Cameron DA, Lago LD, Donnelly JP, Kearney N, et al. 2010 update of EORTC guidelines for the use of granulocytecolony stimulating factor to reduce the incidence of chemotherapy-induced febrile neutropenia in adult patients with lymphoproliferative disorders and solid tumours. European Journal of Cancer 2011;47(1):8-32.   DOI
2 Hershman D, Neugut AI, Jacobson JS, Wang J, Tsai WY, McBride R, et al. Acute myeloid leukemia or myelodysplastic syndrome following use of granulocyte colony-stimulating factors during breast cancer adjuvant chemotherapy. Journal of the National Cancer Institute 2007;99(3):196-205.   DOI
3 Clavarezza M, Del Mastro L, Pronzato P, Bruzzi P, Venturini M. Re: Acute myeloid leukemia or myelodysplastic syndrome following use of granulocyte colony-stimulating factors during breast cancer adjuvant chemotherapy. Journal of the National Cancer Institute 2007;99(13):1050-1.   DOI
4 Mao HJ, Wu HH, Bu LL, Zhou YB, Sun J, Sun PL. Relationship between electroacupunctureinduced regulatory effect on leukocytes and the caliber of splenic sinusoid basal lamina eyehole on rabbits. Zhen ci yanjiu=Acupuncture research 2008;33(5):291-5.
5 Fu H, Chen B, Hong S, Guo Y. Acupuncture Therapy for the Treatment of Myelosuppression after Chemotherapy: A Literature Review over the Past 10 Years. Journal of Acupuncture and Meridian Studies 2015;8(3):122-6.   DOI
6 Lu W, Hu D, Dean-Clower E, Doherty-Gilman A, Legedza AT, Lee H, et al. Acupuncture for chemotherapy-induced leukopenia: exploratory meta-analysis of randomized controlled trials. Journal of the Society for Integrative Oncology 2007;5(1):1-10.   DOI
7 Crawford J, Barth Geller G. Prevention and treatment of chemotherapy-induced neutropenia. Clinical Advances in Hematology and Oncology 2013;11(8):514-7.
8 Lee JH, Jang E, Jung MH, Ha KT, Han C. Clinical effectiveness of acupuncture in the treatment of chemotherapy-induced leukopenia: A systematic review. European Journal of Integrative Medicine 2016;8(5):802-8.   DOI
9 Kim SY, Choi JY, Yun YJ, Park SH, Han CW. A Case Report of Long-term Acupuncture Treatment in Bortezomib Induced Peripheral Neuropathy. Korean Journal of Acupuncture 2015;32(4):208-12.   DOI
10 Folinic acid, fluorouracil and oxaliplatin (FOLFOX). Available from: URL:http://www.cancerresearchuk.org/about-cancer/cancer-in-general/treatment/cancer-drugs/drugs/folfox
11 Bevacizumab (Avastin). Available from: URL:http://www.cancerresearchuk.org/about-cancer/cancerin-general/treatment/cancer-drugs/drugs/bevacizumab
12 Filgrastim. Available from: URL:https://www.drugs.com/monograph/filgrastim.html
13 Lu W, Matulonis UA, Doherty-Gilman A, Lee H, Dean-Clower E, Rosulek A, et al. Acupuncture for chemotherapy-induced neutropenia in patients with gynecologic malignancies: a pilot randomized, sham-controlled clinical trial. Journal of alternative and complementary medicine 2009;15(7):745-53.   DOI
14 Han YF, Gong Z, Huang LQ, Xia X, Zhao WJ. Clinical study on acupuncture for leukopenia induced by chemotherapy. Zhongguozhenjiu = Chinese acupuncture & moxibustion 2010;30(10):802-5.
15 Longo DL. Approach to the Patient with Cancer. In: Kasper D, Fauci A, Hauser S, Longo D, Jameson JL, Loscalzo J, editors. Harrison's Principles of Internal Medicine, 19e. New York, NY: McGraw-Hill Education; 2015.
16 Richard AH, Michelle AC, Richard F, Jose AR, Karen W. Pharmacology, 5th ed. Philadelphia: LWW; 2011.
17 Lyman GH, Lyman CH, Agboola O. Risk models for predicting chemotherapy-induced neutropenia. Oncologist 2005;10(6):427-37.   DOI
18 Crawford J, Dale DC, Lyman GH. Chemotherapyinduced neutropenia. Cancer 2004;100(2):228-37.   DOI
19 Li H, Ma Q, Al P, Zhang H, Li M. Treatment of chemotherapy-induced leucopenia in patients with malignant tumor by Chinese herbal medicine: a systematic review and meta-analysis of randomized clinical trials. Zhongguo Zhong xi yijie he zazhi Zhongguo Zhongxiyijiehezazhi = Chinese journal of integrated traditional and Western medicine / Zhongguo Zhong xi yijie he xuehui, Zhongguo Zhongyiyanjiu yuan zhu ban 2015;35(2):157-66.
20 Kuderer NM, Dale DC, Crawford J, Cosler LE, Lyman GH. Mortality, morbidity, and cost associated with febrile neutropenia in adult cancer patients. Cancer 2006;106(10):2258-66.   DOI