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http://dx.doi.org/10.22246/jikm.2016.37.4.669

A Clinical Case Report of Endoscopic Reflux Esophagitis with Gastric Dysmotility Treated with Korean Traditional Medical Therapy  

Yoon, Sang-hyub (Dept. of Gastroenterology, College of Oriental Medicine, Kyung-Hee University)
Publication Information
The Journal of Internal Korean Medicine / v.37, no.4, 2016 , pp. 669-677 More about this Journal
Abstract
Reflux esophagitis is a common disease in developed nations. We describe the case of a female patient with endoscopic reflux esophagitis complicated by gastric dysmotility. Both electrogastrography and enterotachography were performed to detect gastric myoelectrical activity and pyloric sphincter function and evaluate gastric motility. The patient was treated only with herbal medications and general acupuncture, with electrical stimulation of the ST.36 (Zusanli) point, in addition to moxibustion therapy. After each primary and secondary treatment, the therapeutic effect was immediately evaluated. At the final follow-up 5 mon after the end of the secondary treatment, the patient’s general condition was assessed, in addition to the mucosa of the esophagus. At follow up, all the patients’ symptoms had disappeared, and the mucosa of the esophagus had returned to normal. We attributed these therapeutic effects to improved gastric dysmotility. To confirm the usefulness of this treatment method, studies of larger numbers of patients with reflux esophagitis treated with Korean traditional medicine are needed.
Keywords
reflux esophagitis; gastric dysmotility; traditional medical therapy;
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Times Cited By KSCI : 18  (Citation Analysis)
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1 Lee PL. Pathophysiology of gastroesophageal reflux disease. Korean J Bronchoesophagol 2002;8(2):5-10.
2 Baek DG, Hwang SI, Rhim EK, Lee YJ, Cho YK, Moon MH, et al. Clinical study on 1 case of reflux esophagitis. Korean J Orient Physiology & Pathology 2004;8(6):1933-7.
3 Kim MJ, Jang IS, Kang SY. A case study of 4 patients with reflux esophagitis who had improved gastroesophageal reflux disease after treatment with SokPyeonAnGel. J Int Korean Med 2015;6(1):40-8.
4 Kim YH, Kim SY, Hwang MW. A case study of Taeumin patient with gastro-esophageal reflux disease(GERD) who treated successfully with Yeoldahanso-tang(Reduohanshao-tang). J of Sasang Constitutional Med 2011;23(1):132-8.
5 El-Serag HB, Sweet S, Winchester CC, Dent J. Update on the epidemiology of gastro-oesophageal reflux disease: a systematic review. Gut 2014;63(6):871-80.   DOI
6 Jung HK. Epidemiology of gastroesophageal reflux disease in Asia: a systemic review. J Neurogastroenterol Motil 2011;17(1):14-27.   DOI
7 Kim N, Lee SW, Cho SI, Park CG, Yang CH, Kim HS, et al. H. pylori and Gerd Study Group of Korean College of Helicobacter and Upper Gastrointestinal Research. The prevalence of and risk factors for erosive oesophagitis and non-erosive reflux disease: a nationwide multicentre prospective study in Korea. Aliment Pharmacol Ther 2008;27(2):173-85.   DOI
8 Choi BH, Kwak MA, Kim DJ, Byun JS. Suppressive effects of Yijintang-gamibang on reflux esophagitis. J Korean Orient Med 2010;31(5):64-81.
9 Lee ST, Kwak MA. Effects of individual herbal components of Yijintang-gamibang in the rat reflux esophagitis. Korean J Orient Int Med 2013;34(2):165-77.
10 Park K, Kwak MA, Kim DJ, Byung JS. Protective effects of Yijin-tang-gamibang aqueous extracts on reflux esophagitis mediated by antioxidant defense systems. Korean J Orient Physiology & Pathology 2010;24(3):416-25.
11 Lee YJ, Park JH, Roh SS. Effects on rats with reflux esophagitis treated with Lonicerae Flos extract. Korean J Orient Physiology & Pathology 2010;24(6):970-5.
12 Jang MW, Lim SW. Experimental study for effect of Banhasasim-tang on mice with reflux esophagitis. Korean J Orient Int Med 2013;34(4):362-74.
13 Choi YJ, Jung TY, Lim SC. Inhibitory effects of Naegwan-acupuncture(PC6) on acute reflux esophagitis rat. J Korean Acupuncture & Moxibustion Society 2013;30(2):31-41.
14 Yoon SH. Association of skin sympathetic tone or cardiovascular reactivity on the fatigue index in patients with functional dyspepsia. Korean J Orient Int Med 2005;26(2):390-7.
15 Kim YI. Reflux esophagitis. Korean J of family practice 2013;3:388-94.
16 Bredenoord AJ, Pandolfino JE, Smout AJ. Gastro-oesophageal reflux disease. Lancet 2013;381(1):1933-42.   DOI
17 Yoon SH. Sympathetic nerve function to electrical response of Ryodoraku point and disarrangement of its meridian location on the anatomical viscera exclude the association between Ryodoraku theory and meridian principle. Korean J Orient Int Med 2011;32(2):259-77.
18 Yoon SH. Postprandial epigastric fullness and pyloric valve disturbance in patients with functional dyspepsia-Analysis of bowel sounds and electrogastrography. Korean J Orient Int Med 2007;28(4):769-78.
19 Yoon SH. Bowel sound recording for structural deformity in the pylorus-duodenum: Report of 3 cases. Korean J Orient Int Med 2015;36(3):276-83.
20 Clark CS, Kraus BB, Sinclair J, Castell DO. Gastroesophageal reflux induced by exercise in healthy volunteers. JAMA 1989;261(24):3599-601.   DOI
21 Han CH, Lee JS, Lim HH, Oh YS, Yoon YK, Kim SG, et al. The significance of gastroesophageal reflux disease(GERD) symptoms in patients with reflux esophagitis. J Neurogastroenterology and motility 2000;6:196-205.
22 Park H. Functional gastrointestinal disorders and overlap syndrome in korea. J Gastroenterol Hepatol 2011;26(Suppl 3):12-4.
23 Quartero AO, de Wit NJ, Lodder AC, Numans ME, Smout AJ, Hoes AW. Disturbed solid-phase gastric emptying in functional dyspepsia: a meta-analysis. Dig Dis Sci 1998;43(9):2028-33.   DOI
24 Lee SW, Chang CS, Lien HC, Peng YC, Wu CY, Yeh HZ. Impact of Overlapping Functional Gastrointestinal Disorders on the Presentation and Quality of Life of Patients with Erosive Esophagitis and Nonerosive Reflux disease. Med Princ Pract 2015;24(5):491-5.   DOI
25 Tomomasa T, Morikawa A, Sandler RH, Mansy HA, Koneko H, Masahiko T, et al. Gastrointestinal sounds and migrating motor complex in fasted humans. Am J Gastroenterol 1999;94(2):374-81.   DOI
26 Yamaguchi K, Yamaguchi T, Odaka T, Saisho H. Evaluation of gastrointestinal motility by computerized analysis of abdominal auscultation findings. J Gastroenterol Hepatol 2006;21(3):510-4.   DOI
27 Horowitz M, Su YC, Rayner CK, Jones KL. Gastroparesis: prevalence, clinical significance and treatment. Can J Gastroenterol 2001;15(12):805-13.   DOI
28 King PM, Pryde A, Heading RC. Transpyloric fluid movement and antroduodenal motility in patients with gastro-oesophageal reflux. Gut 1987;28(5):545-8.   DOI
29 King PM, Adam RD, Pryde A, McDicken WN, Heading RC. Relationships of human antroduodenal motility and transpyloric fluid movement:non-invasive observations with real-time ultrasound. Gut 1984;25(12):1384-91.   DOI
30 Buckles DC, Sarosiek I, McMillin C, McCallum RW. Delayed gastric emptying in gastroesophageal reflux disease: reassessment with new methods and symptomatic correlations. Am J Med Sci 2004;327(1):1-4.   DOI
31 McCallum RW, Berkowitz DM, Lerner E. Gastric emptying in patients with gastroesophageal reflux. Gastroenterology 1981;80(2):285-91.
32 Hong JH, Yoon SH, Kim JS, Ryu BH. Effect of Sojukgunbihwan granule on gastric motility in rats. Korean J Orient Int Med 2006;27(1):276-87.
33 Seon JK, Yoon SH. Effect of partial pyloric obstruction on body weight, gastric juice, gastric surface area and gastric edema in normal intact rats and/or vagotomized rats. Korean J Orient Int Med 2012;33(1):26-38.
34 Soykan I, Lin Z, Jones S, Chen J, McCallum RW. Gastric myoelectrical activity, gastric emptying and correlations with dyspepsia symptoms in patients with gastroesophageal reflux. J Investig Med 1997;45(8):483-7.
35 Kim JN, Song HJ, Lim B, Kwon YK, Kim BJ. Modulation of pacemaker potentials by Pyungwi-San in interstitial cells of cajal from murine small intestine. J Pharmacopuncture 2013;16(1):43-9.   DOI
36 Yin J, Chen JD. Gastrointestinal motility disorders and acupuncture. Auton Neurosci 2010;157(1-2):31-7.   DOI
37 Takahashi T. Effect and mechanism of acupuncture on gastrointestinal diseases. Int Rev Neurobiol 2013;111:273-94.
38 Song J, Yin J, Sallam HS, Bai T, Chen Y, Chen JD. Electroacupuncture improves burn-induced impairment in gastric motility mediated via the vagal mechanism in rats. Neurogastroenterol Motil 2013;25(10):807-e635.
39 Liu JH, Yan J, Yi SX, Chang XR, Lin YP, Hu JM. Effects of electroacupuncture on gastric myoelectric activity and substance P in the dorsal vagal complex of rats. Neurosci Lett 2004;356(2):99-102.   DOI
40 Yin J, Chen J, Chen JD. Ameliorating effects and mechanisms of electroacupuncture on gastric dysrhythmia, delayed emptying, and impaired accommodation in diabetic rats. Am J Physiol Gastrointest Liver Physiol 2010;298(4):G563-70.   DOI
41 Park JW, Yoon SW. A clinical case report of non-erosive reflux disease treated with traditional oriental medicine. Korean J Orient Int Med 2006;27(4):991-8.
42 Tabosa A, Yamamura Y, Forno ER, Mello LE. A comparative study of the effects of electroacupuncture and moxibustion in the gastrointestinal motility of the rat. Dig Dis Sci 2004;49(4):602-10.   DOI
43 Ryu JM, Yoon SH, Jang SY, Kim HK, Lee JS, Eom GH, et al. Effects of traditional Korean medical therapy on gastric myoelectrical activity in patient with functional dyspepsia. Korean J Orient Int Med 2005;26(2):360-8.
44 Kim YS, Yoon SH. Combination effects of Zusanli(ST36) electroacupuncture and manual acupuncture of other acupoints on gastric vagal nerve activity and pyloric valve function in patients with functional dyspepsia. Korean J Orient Int Med 2008;29(3):621-8.
45 Kim BS, Lim HY, Oh JH, Kim DW, Choi BH, Hur JI, et al. Seven cases of non-erosive gastroesophageal reflux disease who were treated by Ljintang-Gamibang and acupuncture. Korean J Orient Int Med 2005;26(4):926-34.