Browse > Article

Analysis of Clinical Characteristics and Treatments among Geriatric Cancer Patients Hospitalized in a Traditional Korean Medical Hospital  

Oh, Hye-kyung (Dept. of Internal Medicine, Korean Medicine Cancer Center, Kyung Hee University Hospital at Gangdong)
Lee, Jee-young (Dept. of Internal Medicine, Korean Medicine Cancer Center, Kyung Hee University Hospital at Gangdong)
Ryu, Han-sung (Dept. of Internal Medicine, Korean Medicine Cancer Center, Kyung Hee University Hospital at Gangdong)
Yoon, Seong-woo (Dept. of Internal Medicine, Korean Medicine Cancer Center, Kyung Hee University Hospital at Gangdong)
Publication Information
The Journal of Internal Korean Medicine / v.37, no.2, 2016 , pp. 412-419 More about this Journal
Abstract
Objective: Because the number of geriatric cancer patients is on the rise but information on treatments for this population is limited, this study aimed to analyze clinical characteristics and the factors that influence treatment decisions among elderly cancer patients.Method: Data on elderly cancer patients (≥65 years of age) who were admitted to a traditional Korean medicine hospital from March 2014 to February 2016 were collected. We compared the clinical characteristics and overall survival rates of the chemotherapy group and the non-chemotherapy group.Results: Nineteen patients were included in this study. Nine people received chemotherapy, and ten people did not receive chemotherapy due to concerns about quality of life. Age, activities of daily living (ADL) score, and Eastern Cooperative Oncology Group (ECOG) performance status all showed differences between the two groups, although median survival times did not differ significantly between the two. Compared with chemotherapy alone, traditional Korean medicine combined with chemotherapy prolonged median survival times.Conclusion: Old age and low ECOG performance status and ADL scores appear to be influential factors for the decision to undergo chemotherapy. Further studies are needed to confirm that these factors influence decisions about cancer treatment methods among geriatric cancer patients.
Keywords
geriatric cancer patients; chemotherapy; Korean medicine hospital;
Citations & Related Records
Times Cited By KSCI : 1  (Citation Analysis)
연도 인용수 순위
1 Presley C, Lilenbaum R. The Treatment of Advanced Lung Cancer in the Elderly : The Role of a Comprehensive Geriatric Assessment and Doublet Chemotherapy. Cancer J 2015;21(5):392-7.   DOI
2 Hurria A. Management of elderly patients with cancer. J Natl Compr Canc Netw 2013;11:698-701.   DOI
3 Park SY. Safety and efficacy of adjuvant therapy after surgery of elderly colon cancer patients 70 years of age or older. Master's thesis, Dept. of Medicine, Chung-Ang University 2015.
4 Shin GY. Study on current use of chemotherapy in elderly patients with colorectal cancer. Master's thesis, Dept. of Clinical Health Science, Ewha Womans University 2012.
5 Lee JS, Cho MR, Lee GJ. Validation of the developed nutritional screening tool for hospital patients. Korean J Nutr 2010;43(2):189-96.   DOI
6 Jatoi A, Foster NR, Egner JR, Burch PA, Stella PJ, Rubin J, et al. Older versus younger patients with metastatic adenocarcinoma of the esophagus, gastroesophagealjunction, and stomach : a pooled analysis of eight consecutive North Central Cancer Treatment Group(NCCTG) trials. Int J Oncol 2010;36:601-6.
7 Saif MW, Lichtman SM. Chemotherapy options and outcomes in older adult patients with colorectal cancer. Crit Rev Oncol Hematol 2009;72:155-69.   DOI
8 de Kock I, Mirhosseini M, Lau F, Thai V, Downing M, Quan H, et al. Conversion of Karnofsky Performance Status(KPS) and Eastern Cooperative Oncology Group Performance Status(ECOG) to Palliative Performance Scale(PPS), and the interchangeability of PPS and KPS in prognostic tools. J Palliat Care 2013;29(3):163-9.
9 Ommundsen N, Wyller TB, Nesbakken A, Jordhøy MS, Bakka A, Skovlund E, et al. Frailty is an independent predictor of survival in older patients with colorectal cancer. Oncologist 2014;19(12):1268-75.   DOI
10 Maltoni M, Caraceni A, Brunelli C, Broeckaert B, Christakis N, Eychmueller S, et al. Prognostic factors in advanced cancer patients: evidence-based clinical recommendations-a study by the Steering Committee of the European Association for Palliative Care. J Clin Oncol 2005;23:6240-8.   DOI
11 Qi F, Zhao L, Zhou A, Zhang B, Li A, Wang Z, et al. The advantages of using traditional Chinese medicine as an adjunctive therapy in the whole course of cancer treatment instead of only terminal stage of cancer. Biosci Trends 2015;9(1):16-34.   DOI
12 Folprecht G, Seymour MT, Saltz L, Douillard JY, Hecker H, Stephens RJ, et al. Irinotecan/Fuorouracil combination in first-line therapy of older and younger patients with metastatic colorectal cancer: combined analysis of 2,691 patients in randomized controlled trials. J Clin Oncol 2008;26(9):1443-51.   DOI
13 United States Census: U.S. Census Bureau projections show a slower growing, older, more diverse nation a half century from now. Available form: http://www.census.gov/newsroom/releases/archives/population/cb12-243.html
14 National Cancer Information Center. Available form: http://www.cancer.go.kr/mbs/cancer/subview.jsp?id=cancer_040401000000
15 Hutchins LF, Unger JM, Crowley JJ, Coltman Jr CA, Albain KS. Underrepresentation of patients 65 years of age or older in cancer-treatment trials. N Engl J Med 1999;341(27):2061-7.   DOI
16 Miguchi M, Shimomura M, Hinoi T, Egi H, Ohdan H. Chemotherapeutic outcomes for metastatic colorectal cancer in elderly patients aged≥75 years: A single-institutional retrospective analysis. Asia Pac J Clin Oncol 2016;12(2):151-8.   DOI
17 Malfuson JV, Etienne A, Turlure P, de Revel T, Thomas X, Contentin N, et al. Risk factors and decision criteria for intensive chemotherapy in older patients with acute myeloid leukemia. Haematologica 2008;93(12):1806-13.   DOI
18 Hamaker ME, Seynaeve C, Wymenga AN, van Tinteren H, Nortier JW, Maartense E, et al. Baseline comprehensive geriatric assessment is associated with toxicity and survival in elderly metastatic breast cancer patients receiving single-agent chemotherapy: Results from the OMEGA study of the Dutch Breast Cancer Trialists’ Group. Breast 2014;23(1):81-7.   DOI