Browse > Article

Case Report of a Lumbar Disc Herniation (LDH) Patient with Chronic Active Hepatitis B  

Jung, You-jin (Dept. of Internal Medicine, Gang-nam Ja-Seng Korean Medicine Hospital)
Kang, Kyung-rae (Dept. of Internal Medicine, Gang-nam Ja-Seng Korean Medicine Hospital)
Lee, Min-su (Dept. of Internal Medicine, Gang-nam Ja-Seng Korean Medicine Hospital)
Choi, A-ryun (Dept. of Internal Medicine, Gang-nam Ja-Seng Korean Medicine Hospital)
Kang, A-hyun (Dept. of Internal Medicine, Gang-nam Ja-Seng Korean Medicine Hospital)
Han, Dong-kun (Dept. of Internal Medicine, Gang-nam Ja-Seng Korean Medicine Hospital)
Song, Woo-sub (Dept. of Internal Medicine, Gang-nam Ja-Seng Korean Medicine Hospital)
Lee, Hyung-chung (Dept. of Internal Medicine, Gang-nam Ja-Seng Korean Medicine Hospital)
Publication Information
The Journal of Internal Korean Medicine / v.37, no.2, 2016 , pp. 374-380 More about this Journal
Abstract
Objective: Although the incidence of chronic hepatitis B has decreased around the world due to widespread national preventative control measures, mortality from the same condition can increase if the condition leads to liver cancer or liver cirrhosis. In most cases, herbal medicine does not show any statistically significant effects related to liver damage, but preconceptions do exist that herbal medicine can be toxic and cause such liver damage. To investigate this situation, this study therefore investigated a patient with hepatitis B who had combined traditional Korean medicine therapy and the use of analgesic drugs during a hospitalization period.Method: A patient with hepatitis B was given combined traditional Korean medicine therapy and the use of analgesic drugs during a hospitalization period.Results: Within 26 days, the patient was free from liver damage during the hospitalization period. She was followed up with a liver function test and was discharged after her condition improved; she also reported decreased back pain.
Keywords
chronic hepatitis B; lumbar disc herniation; herbal medicine; liver function test (LFT); drug induced liver injury (DILI);
Citations & Related Records
Times Cited By KSCI : 2  (Citation Analysis)
연도 인용수 순위
1 Kim JC, Park HM, Cho HS, Park JH, Lee JE, Song CH, et al. Comparison of Liver Function Test Score by Herbal Medication Duration. Journal of Internal Korean medicine 2005;fal(1):37-45.
2 Seo YH, Cho SB, Joo YE, Kim HS. Clinical Analysis of 111 patients with hepatic injury caused by herbal medicine and health foods. Clinical and Molecular Hepatology 2001;7(2s):95.
3 Jung KH. The Effects of Samhwangsasim-tang Extracts on Ambulatory Blood Pressure in Mild Hypertensive Patients with Stroke. Journal of oriental adultdisease 2002;8(1):30-4.
4 Kim DW, Lee UJ, An IH, Ban JS, Ryu CY. A study on the effect of prolonged administration of different oriental medicines on the liver function. Journal of Korean oriental medicine 1993;14(2):245-53.
5 Jung HS, Jung H, Kim TS. The effects of herbal medicine administraion on liver injury of clinical patient. Journal of Korean oriental internal medicine 2000;21(2):349-54.
6 Yoon YK, Sun TC, Chou LS, Jung DY. A Clinical Study about Capability of hepatotoxicity associated with Chungsimyeonjatang. Journal of Korean oriental internal medicine 2003;24(4):792-5.
7 Melchart D, Linde K, Hager S, Kaesmayr J, Shaw D, Bauer R, et al. Monitoring of liver enzymes in patients treated with traditional Chinese drugs. Complementary Therapies in Med 1999;7(4):208-16.   DOI
8 AI-Khafaji M. Monitoring of liver enzymes inpatients on Chinese medicine. Journal of Chinese Medicine 2000;62:6-10.
9 Mantani N, Kogure T, Sakai S, Goto H, Shibahara N, Kita T, et al. Incidence and clinical features of liver injury related to Kampo medicine in 2,496 cases between 1979 and 1999: Problems of the lymphocyte transformation test as a diagnostic method. International Journal of Phytotherapy and Phytopharmacology 2002;9(4):280-7.   DOI
10 Choi HS, Jeong TY. One Case of Drug-Induced Liver Injury Treated with Saenggangeonbi-tang. Journal of Korean oriental internal medicine 2004;24(4):207-11.
11 Ministry of Health & Welfare KCfDCaP. The Third Korea National Health and Nutrition Examination Survey(KNHANES Ⅲ), 2005: Health Examination. Ministry of Health & Welfare 2006;68.
12 Kim JH, Kim C, Kim SG, Jang HV, Han JM, Ye SJ, et al. Analysis of Studies on Combined Medication of the Oriental and the Western Medicines. Journal of Preventive Korean medicine 2009;13(3):1-18.
13 Choo WJ, Kim HC, Seo MS, Choi JW, Jung SY, Kim SJ, et al. The Effectiveness of Combined Medication with Herbal Medicine and Western Analgesic Drugs on LFT Levels of the Admitted Patients Diagnosed as Herniated Intervertebral Disc (HIVD). Journal of Internal Korean medicine. 2013;fall(9):237-44.
14 Sim JG, Suh SJ. Prevalence and its changes of hepatitis B viral markers from 1988 to 1993 in Korean children. Korean J Pediatr 1995;38(11):1535-9.
15 Chae HB, Kim JH, Kim JK, Yim HJ. Current status of liver diseases in Korea: hepatitis B. The Korean Journal of Hepatology 2009;15(60):13-24.   DOI
16 Korea centers for disease control and prevention. The fourth Korea National Health and Nutrition Examination Survey (KNHANES IV), 2007. Seoul, Republic of Korea: 2008, p. 277.
17 Park JK, Lee JH, Yang HJ, Kwon SY, Woo HJ, Kim YC. A case of Yinjinchunggan-tang Treated patient with chronic Hepatitis B Relapsed after Interferon therapy. Journal of Internal Koreanmedicine 2011;spr(1):174-9.
18 Kim NH, Jung HY, Cho SY, Park SU, Park JM, Ko CN. Liver enzyme abnormalities during concurrent use of herbal and conventional medicines in Korea: A retrospective study. Phytomedicine 2011;18(14):1208-13.   DOI
19 Bellet F. Hepatotoxicity in drug development:detection, significance and solutions. Journal of Hepatol 1997;26(2):26-36.   DOI
20 Bak HM. Effects of Herbal and Western Medicines on Liver Functions and Characteristics of Subjects out of Normal Range in Liver Function Tests. Sang-ji University 2006;8:35-7.
21 Sin GT. Steps to internal medicine Part6. Seoul: JungDam; 2002, p. 177-214.
22 Ahn BM. Diagnosis and Treatment in Drug-induced Liver damage. Clinical and Molecular Hepatology 2001;7(suppl 1):45-63.
23 Benichou C. Criteria of drug-induced liver disorders-Report of an International Consensus Meeting. Journal of Hepatol 1990;11(2):272-6.   DOI