Browse > Article

Systemic Reviews of Domestic Experimental Studies of Herbal Medicines Used for Hypothyroidism since 2000  

Lee, Min-hye (Dept. of Oriental Internal medicine, Gil Oriental Medical Hospital, Ga-Chon University)
Choi, You-kyung (Dept. of Oriental Internal medicine, Gil Oriental Medical Hospital, Ga-Chon University)
Publication Information
The Journal of Internal Korean Medicine / v.36, no.4, 2015 , pp. 570-581 More about this Journal
Abstract
Objectives The purpose of this study was to investigate the experimental studies which was performed by single or complex herbal medicines on hypothyroidism.Methods I searched the domestic experimental studies about single or complex herbal medicines’ effects on hypothyroidism that published since 2000 on 4 Korean databases by keywords, ‘thyroid gland’, ‘hypofunction’, ‘hypothyroidism’.Results 11 single herbal medicines and 9 complex herbal medicines in 20 experimental studies have reported their effectiveness and safetiness in PTU-induced hypothyroidism rats by evaluating the changes of several biochemical and hematological indexes.Conclusions In order to make new and more effective medicines on hypothyroidism, there should be further studies by using combinations of herbal medicines and the differences of their mechanisms.
Keywords
hypothyroidism; experimental study; herbal medicine;
Citations & Related Records
Times Cited By KSCI : 1  (Citation Analysis)
연도 인용수 순위
1 전국 한의과대학 신계내과학교실. 腎系內科學. 서울: 군자출판사; 2011, p. 282-6.
2 대한내분비학회. 내분비대사학. 2nd edition. 서울: 군자출판사; 2011, p. 168-79.
3 조보연. 임상갑상선학. 2nd edition. 서울: 고려의학; 2001, p. 409-41.
4 Escobar-Morreale HF, Botella-Carretero JI, Morreale de Escobar G. Treatment of hypothyroidism with levothyroxine or a combination of levothyroxine plus L-triiodothyronine. Best Pract Res Clin Endocrinol Metab 2015;29(1):57-75.   DOI
5 Wiersinga WM. Thyroid hormone replacement therapy. Horm Res 2001;56:74-81.   DOI
6 박종효, 한양희. 腎과 갑상선의 상관성에 관한 고찰. 대한한방내과학회지 1997;18(2):305-31.
7 杜鎬京. 東醫腎系學. 서울: 東洋醫學硏究院; 1993, p. 729, 867-74, 1042, 1056-65.
8 박수연, 금홍진, 금종한, 최정화. 갑상선기능저하증 환자 一例에 관한 臨床報告. 한방안이비인후피부과학회지 2001;14(2):284-6.
9 이종빈, 박상우, 정호영, 김철중, 조충식. A clinical report of Herbal treatment effect on a subclinical hypothyroidism patient. 한의학연구소 논문집 2012; 21(1):97-101.
10 Koo JS, Kim BH, Seo BI. A clinical study on a patient with hypothyroidism. J Korean Herbology 2014;29(5):17-21.   DOI
11 Erdamar H, Demirci H, Yaman H, Erbil MK, Yakar T, Sancak B, et al. The effect of hypothyroidism, hyperthyroidism, and their treatment on parameters of oxidative stress and antioxidant status. Clin Chem Lab Med 2008;46(7):1004-10.   DOI
12 Bhanja S, Chainy GB. PTU-induced hypothyroidism modulated antioxidant defence status in the developing cerebellum. Int J Dev Neurosci 2010; 28(3):251-62.   DOI
13 전국 한의과대학 본초학교수 공편저. 본초학. 서울: 영림사; 2011, p. 149-51, 240-1, 312-3, 334-5, 337-8, 550-1, 531-3, 549-50, 568-9, 602-3, 676-7.
14 최호승, 김영목, 임종국, 손윤희, 남경수, 김철호, 등. 감궁탕 가미방이 갑상샘 기능장애에 미치는 효과. 동의생리병리학회지 2003;17:648-55.
15 남경수, 손윤희, 백태선, 김철호, 임종국, 황철원. Anti-thyrogloblin monoclonal antibody의 제작 및 특성. 한국생명과학회지 2002;12:460-3.
16 Roti E, Minelli R, Gardini E, Braverman LE. The use and misuse of thyroid hormone. Endocr Rev 1993;14:401-24.
17 김민선, 윤초아, 조영민, 정혜승, 신찬수, 박경수, 등. 랫트에서 단기간의 갑상선 기능 변화에 따른 혈중 랩틴 농도의 변화. 대한내분비학회지 2002;17:197-205.
18 안세영. 갑상선클리닉. 서울: 성보사; 2004, p. 210-3, 241-8.
19 김동현, 김형민, 류종훈, 엄재영, 김상찬, 양재하, 조민경, 임종필, 홍승헌. 한방양리학. 서울: 신일상사; 2006, p. 186-92.
20 大韓東醫生理學會 編. 東醫生理學. 서울: 慶熙大學校出版局; 1993, p. 321.
21 Suh SJ, Chung TW, Son MJ, Kim SH, Moon TC, Son KH, et al. The naturally occurring biflavonoid, ochnaflavone, inhibits LPS-induced iNOS expression, which is mediated by ERK1/2 via NF-kappaB regulation, in RAW264.7 cells. Arch Biochem Biophys 2006;447(2):136-46.   DOI
22 Guo Y, Matsumoto T, Kikuchi Y, Ikejima T, Wang B, Yamada H. Effects of a pectic polysaccharide from a medicinal herb, the roots of Bupleurum falcatum L. on interleukin 6 production of murine B cells and B cell lines. Immunopharmacology 2000;49(3):307-16.   DOI
23 Luo ZH. The combined modulating effects of cerium nitrate with certain Chinese traditional drugs on altered cell-mediated immunities in scald mice. Zhonghua Wai Ke Za Zhi 1990; 28(9):562-65.
24 Choi CW, Jung HA, Kang SS, Choi JS. Antioxidant constituents and a new triterpenoid glycoside from Flos Lonicerae. Arch Pharm Res 2007; 30(1):1-7.   DOI
25 張仲景. 傷寒論講解. 河南: 河南科學技術出版社; 1988, p. 102-4, 354-7.
26 이상인, 김동걸, 이영종, 노승현, 주영승. 方劑學. 서울: 영림사; 1990, p. 158-9, 187-8.
27 Kim JJ. Dongyang-uihak Jinryo-yogam(東洋醫學 診療要鑑). Seoul: Institute of Oriental Medicine; 1974, p. 176-7.
28 Heo J. Donguibogam. Gyeongnam: DonguiBogam publishing company; 2005, p. 1261-2.
29 張介賓. 景岳全書. 서울: 一中社; 1992, p. 102-4.
30 龔廷賢. 萬病回春. 서울: 행림서원; 1975, p. 204-5.
31 민헌기, 최영길, 고창순, 허갑범, 이태희, 이홍규. 내분비학. 서울: 고려의학; 1999, p. 301-4.
32 Lee JM. Donguisusebowon(東醫壽世保元). Seoul: Eulyoo Publishing Company; 2002, p. 277-8.
33 Choi BC, Ahn TW. Anti-oxidant Effect of Hyangsayangyi-tang Decoction in Stomach, Spleen and Pancreas Cell of SD Rats. J Sasang Constitutional Med 2008;20:72-84.
34 Hong ND, Chang IK, Kim NY, Lee IS. Studies on the Efficacy of Combined Preparations of Crude Drug(XXXIX). -Effect of HyangsayangweeTang on the Stomach and Intestinal Disorder-. J Korean Pharmacogn 1989;20:188-95.
35 Dory L, Roheim PS. Rat plasma lipoproteins and apolipoproteins in experimental hypothyroidism. J Lipid Res 1981;22(2):287-96.
36 Teixeira Px, Reuters VS, Ferreira Mx, Almeida CP, Reis Fx, Buescu A, et al. Lipid profile in different degrees of hypothyroidism and effects of levothyroxine replacement in mild thyroid failure. Transl Res 2008;151(4):224-31.   DOI
37 Subudhi U, Das K, Paital B, Bhanja S, Chainy GB. Supplementation of curcumin and vitamin E enhances oxidative stress, but restores hepatic histoarchitecture in hypothyroid rats. Life Sci 2009;84:372-9.   DOI
38 Ito M, Arishima T, Kudo T, Nishihara E, Ohye H, Kubota S, et al. Effect of levo-thyroxine replacement on non-high-density lipoprotein cholesterol in hypothyroid patients. J Clin Endocrinol Metab 2007;92(2):608-11.   DOI
39 Das K, Chainy GB. Modulation of rat liver mitochondrial antioxidant defence system by thyroid hormone. Biochim Biophys Acta 2001; 1537:1-13.   DOI