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Effect of Heating Condition and Panax Ginseng on Body Temperature, Hematological Changes, and Immune Response in Rat  

Yi, Seo-Ra (Dept. of Oriental Internal Medicine, College of Oriental Medicine, Kyung-Hee University)
Lee, In-Hee (Dept. of Oriental Internal Medicine, College of Oriental Medicine, Kyung-Hee University)
Kim, Min-Ji (Dept. of Oriental Internal Medicine, College of Oriental Medicine, Kyung-Hee University)
Lew, Jae-Hwan (East-west Medicine Department, Graduate School of East-west Medical Science, Kyung-Hee University)
Publication Information
The Journal of Internal Korean Medicine / v.35, no.1, 2014 , pp. 59-69 More about this Journal
Abstract
Objectives : This study was designed to test the effect of heating condition and Panax ginseng on body temperature, hematologicala changes, and immune response. Methods : The extract from Panax ginseng was made by the pharmacy department of Kyung Hee Oriental Medical Hospital. The animals were divided into four groups; control, room temperature Panax ginseng (G), $28^{\circ}C$ heating, and $28^{\circ}C$ heating Panax ginseng (heating G). Each group has 8 Sprague-Dawley rats. We measured body weight & temperature twice a week. After 2 weeks of experiment, serum lipid level, WBC, differential count, lymphocyte proliferation and immune cytokine concentration were measured. Results : 1. Simultaneous application of heating condition and Panax ginseng induced decreased body weight and increased body temperature. 2. Simultaneous application of heating condition and Panax ginseng induced decreased AST, ALT and BUN. 3. Simultaneous application of heating condition and Panax ginseng tended to decrease TNF-${\alpha}$ concentration, while application of room temperature and Panax ginseng tended to increase TNF-${\alpha}$ concentration. Conclusions : Simultaneous application of heating condition and Panax ginseng decreseas body weight, increases, body temperature and has a tendency to decrease TNF-${\alpha}$ concentration.
Keywords
heating; Panax ginseng; body weight; body temperature; immune; TNF-${\alpha}$;
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Times Cited By KSCI : 6  (Citation Analysis)
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