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Case Study of a Breast Cancer Patient Accompanying with Hot Flush by Tamoxifen Whose Condition Was Improved by Jayeumganghwa-tang  

Zheng, Hong-Mei (East-West Cancer Center, Dunsan Oriental Hospital, Dae-Jeon University)
Lee, Yeon-Weol (East-West Cancer Center, Dunsan Oriental Hospital, Dae-Jeon University)
Yoo, Hwa-Seung (East-West Cancer Center, Dunsan Oriental Hospital, Dae-Jeon University)
Cho, Chong-Kwan (East-West Cancer Center, Dunsan Oriental Hospital, Dae-Jeon University)
Publication Information
The Journal of Internal Korean Medicine / v.31, no.2, 2010 , pp. 395-400 More about this Journal
Abstract
Objective : To observe the effectiveness of Jayeumganghwa-tang on hot flush of a breast cancer patient who takes tamoxifen. Methods : For six weeks a dosage witch contained 13.92g of Jayeumganghwa-tang was administered 3 times (30 mins after meal) per day, for improvement of hot flush. No other therapies like hormone therapy or substituted therapy were done. Results : As a result of 6 weeks of Jayeumganghwa-tang therapy, the patient who suffered hot flush on taking tamoxifen showed improvement on several indices, including frequency, intensity and point of hot flush, Beck Depression Inventory-K (BDI-K) which shows uneasiness and sadness, and also Functional Assessment Cancer Therapy - Breast (FACT-B) which is an index of life quality of breast cancer patients. But no changes on female hormones like follicle-stimulating hormone (FSH) or luteinizing hormone (LH) were observed. Conclusion : This case demonstrates 6 weeks of Jayeumganghwa-tang taking had no effect on female hormones but can reduce the hot flush by tamoxifen. This shows minimum evidence of safety and efficacy of Jayeumganghwa-tang on hot flush of breast cancer patient. However this is a single case study so further case-series research should be compiled.
Keywords
Breast cancer; Jayeumganghwa-tang; Hot flush;
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