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Oxidative Stress in the Cell and Antioxidant Activity of Kalopanax Pictus Extracts  

Kim, Sea-Hyun (Div. Special Purpose Tree, Korea Forest Research Institute)
Park, Youngki (Div. Special Purpose Tree, Korea Forest Research Institute)
Jang, Yong-Seok (Div. Special Purpose Tree, Korea Forest Research Institute)
Han, Jingyu (Div. Special Purpose Tree, Korea Forest Research Institute)
Chung, Hun-Gwan (Div. Special Purpose Tree, Korea Forest Research Institute)
Publication Information
Journal of the Korean Wood Science and Technology / v.35, no.6, 2007 , pp. 126-134 More about this Journal
Abstract
This study reviewed the application of an extract from Kalopanax pictus stem bark and root bark as natural antioxidants. To investigate the effect on cell toxic level against transformed mouse fibroblast L929 in formula added with various extracts from Kalopanax pictus stem bark and root bark, this experiment was carried out by in vitro cytotoxicity method. Using DCFA-DA method, oxidative stress in cell was measured with other antioxidant activity methods including DPPH assay and NBT assay. Active oxygen inhibition rate for root bark insoluble hot water extracts showed the highest with 57.9% for 15 min treatment. In DPPH and NBT test, antioxidant activities of methanol extract from stem bark and insoluble hot water extract from stem bark were 96% (at 0.1%) and 95% (at 0.5%), respectively.
Keywords
Kalopanax pictus; cell toxicity; antioxidative stress; antioxidant activity;
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Times Cited By KSCI : 1  (Citation Analysis)
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