Contamination Investigation and Risk Characterization on the Polycyclic Aromatic Hydrocarbon of Agricultural Products Used for Food and Medicine |
Park, Young-Ae
(Gangbuk Agro-Fishery Products & Herbal Medicine Inspection Center, Seoul Metropolitan Government Research Institute of Public Health and Environment)
Ko, Suk-Kyung (Gangbuk Agro-Fishery Products & Herbal Medicine Inspection Center, Seoul Metropolitan Government Research Institute of Public Health and Environment) Jo, Sung-Ae (Gangbuk Agro-Fishery Products & Herbal Medicine Inspection Center, Seoul Metropolitan Government Research Institute of Public Health and Environment) Jung, Sam-Ju (Gangbuk Agro-Fishery Products & Herbal Medicine Inspection Center, Seoul Metropolitan Government Research Institute of Public Health and Environment) Choi, Eun-Jung (Gangbuk Agro-Fishery Products & Herbal Medicine Inspection Center, Seoul Metropolitan Government Research Institute of Public Health and Environment) Hong, Sung-Cho (Gangbuk Agro-Fishery Products & Herbal Medicine Inspection Center, Seoul Metropolitan Government Research Institute of Public Health and Environment) Cho, Seok-Ju (Gangbuk Agro-Fishery Products & Herbal Medicine Inspection Center, Seoul Metropolitan Government Research Institute of Public Health and Environment) Jung, Ji-Hun (Gangbuk Agro-Fishery Products & Herbal Medicine Inspection Center, Seoul Metropolitan Government Research Institute of Public Health and Environment) Park, Ju-Sung (Gangbuk Agro-Fishery Products & Herbal Medicine Inspection Center, Seoul Metropolitan Government Research Institute of Public Health and Environment) |
1 | Ministry of Food and Drug Safety (MFDS) (2015) Guidelines for validation of analysis method in pharmaceuticals. Available from: https://www.nifds.go.kr/brd/m_15/down.do?brd_id=167&seq=10029&data_tp=A&file_seq=1. Accessed 23 October 2020. |
2 | Ministry of Food and Drug Safety (MFDS) (2019) Common guidelines for risk assessment of products applied products. Available from: https://www.mfds.go.kr/brd/m_210/view.do?seq=14364&srchFr=&srchTo=&srchWord=&srchTp=&itm_seq_1=0&itm_seq_2=0&multi_itm_seq=0&company_cd=&com-pany_nm=&page=20. Accessed 17 December 2020. |
3 | Ministry of Food and Drug Safety (MFDS) (2018) Risk assessment of polycyclic aromatic hydrocarbons in food. Available from: https://www.nifds.go.kr/brd/m_271/view.do?seq =12537&srchFr=&srchTo=&srchWord=&srchTp=&itm_se-q_1=0&itm_seq_2=0&multi_itm_seq=0&company_cd=&company_nm =&page=1. Accessed 7 December 2021. |
4 | Ministry of Food and Drug Safety (MFDS) (2018) Explanation on the determination of residual pesticides not established criteria for medicinal herb. Available from: https://www.mfds.go.kr/brd/m_210/view.do?seq=14475&srchFr=&srchTo=&srchWord=&srchTp=&itm_seq_1=0&itm_seq_2=0&multi_itm_seq=0&company_cd=&company_nm=&page=2. Accessed 15 March 2021. |
5 | Kosis (2020) Korean statistical information service. Available from: https://kosis.kr/statHtml/statHtml.do?orgId=350&tblId=DT_35007_N132&vw_cd=MT_ZTITLE&list_id=350_35007_ A007&seqNo=&lang_mode=ko&language=kor&obj_var_id=&itm_id=&conn_path=MT_ZTITLE. Accessed 9 May 2022. |
6 | Kosis (2020) Korean statistical information service. Available from: https://kosis.kr/statHtml/statHtml.do?orgId=101&tblId=DT_1B41&vw_cd=&list_id=&scrId=&seqNo=&lang_mode=ko&obj_var_id=&itm_id=&conn_path=E1&docId=01394&markType=S&itmNm=%EC%A0%84%EA%B5%AD. Accessed 9 May 2022. |
7 | Roger, C. (1997) Validation of chromatographic methods in biomedical analysis viewpoint and discussion. J. Chromatogr. 689: 175-180. DOI |
8 | Ministry of Food and Drug Safety (MFDS) (2018) Developing tools for assessing uncertainty and variability in risk assessment for food. Available from: https://doi.org/10.23000/TRKO201900003438. Accessed 17 June 2022. |
9 | IARC (2006) Monographs on the evaluation of carcinogenic risks to humans. 92. |
10 | Hu, S. J., Woo, G. J. and Choi, D. M. (2007) Determination of benzo(a)pyrene in olive oil. Anal. Sci. Technol. 20: 170-175. |
11 | Ministry of Food and Drug Safety (MFDS) (2007) KFDA's Notification NO. 2007-68, Cheongju, Korea. |
12 | Whang, K. H., Yeom, M. S., Lee, H. J., Jo, A. R., Choi, E. J., Heo, M. J. and Kwon, M. J. (2020) A Survey on benzo (a)pyrene contamination in Amomum tsao-ko Fruit of medicinal herbs. Kor. J. Pharmacogn. 51: 146-150. DOI |
13 | Ministry of Food and Drug Safety (MFDS) (2021) The Korean Herbal Pharmacopoeia, Cheongju, Korea. |
14 | Zhongzhen, Z. and Hubiao, C. (2018) Chinese medicinal identification, 59-385, Korean Studies Information Co., Ltd., Paju, Gyeonggido, Korea. |
15 | Park, Y. A., Jung, S. Y., Kim, N. H., Lee, Y. J., Jo, J. Y., Kim, U. H., Kim, J. K., Hwang, I. S., Lee, S. M., Oh, Y. H. and Jeong, K. (2018) Establishment of activated carbon treatment conditions to reduce polycyclic aromatic hydrocarbons contents in soybean oil and perilla oil. Kor. J. Food Technol. 50: 1-7. |
16 | European Food Safety Authority (EFSA) (2008) Polycyclic aromatic hydrocarbons in food. Scientific opinion of the panel on contaminants in the food chain. The EFSA J. 724: 1-114. |
17 | WHO (2000) Air Quality Guidelines. 2nd ed. WHO Regional office for Europe, 1-24, Copenhagen, Denmark. |
18 | European Commission (EC) (2002) Opinion of the scientific committee on food on the risks to human health of polycyclic aromatic hydrocarbons in food. EU, Brussels, Belgium. |
19 | EFSA (2008) EFSA/DATEX/002 Fingings of the EFSA Data Collection on Polycyclic Aromatic Hydrocarbons in Food. Available from: https://www.efsa.europa.eu/en/efsajournal/pub/rn-33. Accessed 23 January 2022. |
20 | Ministry of Food and Drug Safety (MFDS) (2010) KFDA's Notification NO. 2010-51, Cheongju, Korea. |
21 | Lee, S. R., Kim, A. K., Kim, S. D., Lee, H. K., Lee, H. J., Ryu, H. J., Lee, J. M., Yu, I. S. and Jung, K. (2017) Monitoring and risk assessment of benzo(a)pyrene content in medicinal herbs. Kor. J. Pharmacogn. 48: 237-242. |
22 | IARC (2010) Monographs on the evaluation of carcinogenic risks to humans, overall evaluations of carcinogenicity. Supplement 92: 33-814. |
23 | Park, Y. A., Ko, S. K., Cho, S. J., Hwang, I. S., Shin, G. Y. and Moon, K. D. (2021) Investigation and risk characterization on the contamination level of herbal medicines without legal benzo(a)pyrene specification. Kor. J. Pharmacogn. 52: 219-227. DOI |
24 | Ministry of Food and Drug Safety (MFDS) (2021) The Korean Pharmacopoeia, Cheongju, Korea. |
25 | Ministry of Food and Drug Safety (MFDS) (2021) Korean Food Code, Cheongju, Korea. |
26 | Food and Drug Administration (KFDA) (2011) Genotoxic carcinogen risk assessment guide. Available from: http://www.nifds.go.kr/brd/m_15/view.do?seq=4733&srchFr=&srchTo=&srchWord=&srchTp=&itm_seq_1=0&itm_seq_2=0&multi_itm_seq=0&company_cd=&company_nm=&page=90. Accessed 10 February 2021. |
27 | Ministry of Food and Drug Safety (MFDS) (2009) The dispensatory on the visual and organoleptic examination of commercial herbs for food and medicine, Cheongju, Korea. |
28 | Ministry of Food and Drug Safety (MFDS) (2019) Analysis method of benzo(a)pyrene in herbal medicine. Available from: https://www.mfds.go.kr/brd/m_218/view.do?seq=33291&srchFr=&srchTo=&srchWord=&srchTp=&itm_seq_1=0&itm_seq_2=0&multi_itm_seq=0&company_cd=&compa-ny_nm=&page=3. Accessed 3 November 2020. |
29 | CODEX Alimentarius Commission (2009) Guidelines for the design and implementation of national regulatory food safety assurance programme associated with the use of veterinary drugs in food producing animals, CAC/GL-71, Rome, Italy. |