Isolation and Synthesis of an Antifungal Metabolite Derived from the Commensal Vaginal Bacterium Dermabacter vaginalis
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So, Jae Seong
(Department of Pharmacy, Woosuk University)
Kwon, Kang Mu (Department of Pharmacy, Woosuk University) Lee, Munseon (Department of Pharmacy, Woosuk University) Kim, Dae Keun (Department of Pharmacy, Woosuk University) Hwang, In Hyun (Department of Pharmacy, Woosuk University) |
1 | Blum, H. E. (2017) The human microbiome. Adv. Med. Sci. 62: 414-420. DOI |
2 | Proctor, L., LoTempio, J., Marquitz, A., Daschner, P., Xi, D., Flores, R., Brown, L., Ranallo, R., Maruvada, P., Regan, K., Lunsford, R.D., Reddy, M. and Caler, L. (2019) A review of 10 years of human microbiome research activities at the US National Institutes of Health, Fiscal Years 2007-2016. Microbiome 7: 31. |
3 | Lin, Y.-P., Chen, W.-C., Cheng, C.-M. and Shen, C.-J. (2021) Vaginal pH value for clinical diagnosis and treatment of common vaginitis. Diagnostics(Basel) 11: 1996. |
4 | Tony-Odigie, A., Wilke, L., Boutin, S., Dalpke, A. H. and Yi, B. (2022) Commensal bacteria in the cystic fibrosis airway microbiome reduce P. aeruginosa induced inflammation. Front. Cell. Infect. Microbiol. 12: 824101. |
5 | Jayatilake, G. S., Thornton, M. P., Leonard, A. C., Grimwade, J. E. and Baker, B. J. (1996) Metabolites from an Antarctic sponge-associated bacterium, Pseudomonas aeruginosa. J. Nat. Prod. 59: 293-296. DOI |
6 | Smits, W. K., Lyras, D., Lacy, D. B., Wilcox, M. H. and Kui- jper, E. J. (2016) Clostridium difficile infection. Nat. Rev. Dis. Primers 2: 16020. |
7 | Gilbert, J. A., Blaser, M. J., Caporaso, J. G., Jansson, J. K., Lynch, S. V. and Knight, R. (2018) Current understanding of the human microbiome. Nat. Med. 24: 392-400. DOI |
8 | Saraf, V. S., Sheikh, S. A., Ahmad, A., Gillevet, P. M., Bokhari, H. and Javed, S. (2021) Vaginal microbiome: normalcy vs dysbiosis. Arch. Microbiol. 203: 3793-3802. DOI |
9 | Borgogna, J.-L. C., Shardell, M. D., Grace, S. G., Santori, E. K., Americus, B., Li, Z., Ulanov, A., Forney, L., Nelson, T. M., Brotman, R. M., Ravel, J. and Yeoman, C. J. (2021) Biogenic amines increase the odds of bacterial vaginosis and affect the growth and lactic acid production by vaginal Lactobacillus spp. Appl. Environ. Microbiol. 87: e03068-20. |
10 | Sobel, J. D. Vaginitis. (1997) N. Engl. J. Med. 337: 1896-1903. DOI |
11 | Chang, D.-H., Rhee, M.-S. and Kim, B.-C. (2016) Derm- abacter vaginalis sp. nov., isolated from human vaginal fluid. Int. J. Syst. Evol. Microbiol. 66: 1881-1886. DOI |
12 | Gautschi, M., Schmid, J. P., Peppard, T. L., Ryan, T. P., Tuorto, R. M. and Yang, X. (1997) Chemical characterization of diketopiperazines in beer. J. Agric. Food Chem. 45: 3183-3189. DOI |
13 | Fernandez-Natal, I., Saez-Nieto, J. A., Medina-Pascual, M. J., Albersmeier, A., Valdezate, S., Guerra-Laso, J. M., Rodriguez, H., Marrodan, T., Parras, T., Tauch, A. and Soriano, F. (2013) Dermabacter hominis: a usually daptomycin-resistant grampositive organism infrequently isolated from human clinical samples. New Microbes New Infect. 1: 35-40. DOI |
14 | Ceccarani, C., Foschi, C., Parolin, C., D'Antuono, A., Gaspari, V., Consolandi, C., Laghi, L., Camboni, T., Vitali, B., Severgnini, M. and Marangoni, A. (2019) Diversity of vaginal microbiome and metabolome during genital infections. Sci. Rep. 9: 14095. |
15 | Shin, H. J., Mondol, M. A. M., Yu, T. K., Lee, H.-S., Lee, Y.-J., Jung, H. J., Kim, J. H. and Kwon, H. J. (2010) An angio- genesis inhibitor isolated from a marine-derived actinomycete, Nocardiopsis sp. 03N67. Phytochem. Lett. 3: 194-197. DOI |
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