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http://dx.doi.org/10.22889/KJP.2020.51.4.297

Determination of Silymarin and Silybin Diastereomers in Korean Milk Thistle using HPLC/UV Analysis  

Kim, Juree (Department of Plant Science and Technology, Chung-Ang University)
Paje, Leo Adrianne (Department of Plant Science and Technology, Chung-Ang University)
Choi, Jung Won (Department of Plant Science and Technology, Chung-Ang University)
Lee, Hak-Dong (Department of Plant Science and Technology, Chung-Ang University)
Shim, Jae Suk (Imsil Herbal Medicine Association)
Shim, Jeehyoung (EL&I Co., Ltd.)
Geraldino, Paul John L. (Department of Biology, University of San Carlos)
Lee, Sanghyun (Department of Plant Science and Technology, Chung-Ang University)
Publication Information
Korean Journal of Pharmacognosy / v.51, no.4, 2020 , pp. 297-301 More about this Journal
Abstract
Silymarin (SM) and silybin diastereomers (SD) in milk thistle (Silybum marianum) were determined using high-performance liquid chromatography and quantified using a reverse-phase column in a gradient elution system. UV detection was performed at 288 nm. The content of SM and SD in milk thistle was 3.236 and 0.553 mg/g DW, respectively. Determining the presence and quantifying the content of SM and SD in milk thistle are vital for the pharmaceutical industry to identify optimal sources for developing health supplements or therapeutics.
Keywords
HPLC; Silybin diastereomer; Silybum marianum; Silymarin;
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Times Cited By KSCI : 2  (Citation Analysis)
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