Browse > Article
http://dx.doi.org/10.22889/KJP.2020.51.3.222

Simultaneous Quantitative Analysis of Mixtures of Ixeridium dentatum (Thunb.) Tzvelev, Plantago asiatica L. and Rumex crispus L. Ethanol Extracts  

Kim, Ga-Ram (College of Pharmacy, Keimyung University)
Kim, Eun-Nam (College of Pharmacy, Keimyung University)
Birasuren, Bayarmaa (Topworld)
Min, Yeonhong (Topworld)
Jeong, Gil-Saeng (College of Pharmacy, Keimyung University)
Publication Information
Korean Journal of Pharmacognosy / v.51, no.3, 2020 , pp. 222-229 More about this Journal
Abstract
Recently, consume for functional cosmetics containing natural products has been greatly increased. In order to develop it as a natural cosmetic material, we selected Ixeridium dentatum (Thunb.) Tzvelev, Plantago asiatica L. and Rumex crispus L. that have antioxidant and anti-inflammatory effects. In this study, simultaneous quantitative analysis of the isolated compounds and natural product complexes (Mix.) were validated using high performance liquid chromatography (HPLC). The isolated six compounds were shown in a large linearity with a correlation coefficient (R2) of 0.99. The limit of detection (LOD) of chlorogenic acid, plantamajoside, acteoside, emodin chrysophanol and physcion were 0.36 ㎍/mL, 0.36 ㎍/mL, 0.37 ㎍/mL, 0.30 ㎍/mL, 0.22 ㎍/mL and 0.12 ㎍/mL, respectively. The limit of quantification (LOQ) of chlorogenic acid, plantamajoside, acteoside, emodin chrysophanol and physcion were 1.10 ㎍/mL, 1.08 ㎍/mL, 1.12 ㎍/mL, 0.99 ㎍/mL, 0.66 ㎍/mL and 0.35 ㎍/mL, respectively. Content analysis showed chlorogenic acid (0.19 ± 0.02%), plantamajoside (0.48 ± 0.01%), acteoside (0.65 ± 0.01%), emodin (1.15 ± 0.11%), chrysophanol (0.73 ± 0.01%) and physcion (0.69 ± 0.09%). Therefore, the results of this study may provide for basic data of standardization research natural cosmetic material development on the I. dentatum, P. asiatica and R. cripus.
Keywords
HPLC; Quantitative; Ixeridium dentatum (Thunb.) Tzvelev; Plantago asiatica L.; Rumex crispus L.;
Citations & Related Records
Times Cited By KSCI : 13  (Citation Analysis)
연도 인용수 순위
1 Yun, K. H., Chi, Y. H., Lee, D. K. and Paik, S. H. (2018) Quantitative analysis of paeoniflorin and paeonol in peony extracts and quality control standards. Appl. Sci. 35: 235-246.
2 Lee, G. B., Yeom, A. R., Kim, D. W., Park, C. M., Joung, M. S., Lee, G. Y. and Jeong, C. S. (2018) Evaluation of Alcea rosea L. callus extract as a natural cosmetic ingredient. J. Soc. Cosmet. Sci. Korea. 44: 295-302.   DOI
3 Park, J. H., Park, S. J., Yoo, G., Kwak, H. J., Oh, Y. and Kim, S. H. (2017) Chemical profiling of the aerial parts and roots of Ixeris dentata using LC QTOF-MS combined with multivariate chemometric analysis. Herb. Med. 3: 12.
4 Karki, S., Park, H. J., Nugroho, A., Kim, E. J., Jung, H. A. and Choi, J. S. (2015) Quantification of major compounds from Ixeris dentata, Ixeris dentata Var. albiflora, and Ixeris sonchifolia and their comparative anti-inflammatory activity in lipopolysaccharide-stimulated RAW 264.7 cells. J. Med. Food. 18: 83-94.   DOI
5 Lee, E. (2011) Effects of Ixeris dentata extract on the production of pro-inflammatory cytokines in the LPS stimulated rat and raw 264.7 cells. Korean J. Plant Res. 24: 604-612.   DOI
6 Park, E. K., Sung, J. H., Trinh, H. T., Bae, E. A., Yun, H. K., Hong, S. S. and Kim, D. H. (2008) Lactic acid bacterial fermentation increases the antiallergic effects of Ixeris dentata. J. Mocrobiol. Biotechnol. 18: 308-313.
7 Lee, H. N., Shin, S. A., Choo, G. S., Kim, H. J., Park, Y. S., Park, B. K., Kim, B. S., Kim, S. K., Cho, S. D., Nam, J. S., Choi, C. S. and Jung, J. Y. (2016) Anticancer effects of Ixeris dentata (Thunb. ex Thunb.) nakai extract on human melanoma cells A375P and A375SM. J. Ethnopharmacol. 194: 1022-1031.   DOI
8 Ahn, J. H., Jo, Y. H., Kim, S. B., Turk, A., Oh, K. E., Hwang, B. Y., Lee, K. Y. and Lee, M. K. (2018) Identification of antioxidant constituents of the aerial part of Plantago asiatica using LC-MS/MS coupled DPPH assay. Phytochem. Lett. 26: 20-24.   DOI
9 Bhattarai, K. R., Lee, H. Y., Kim, S. H., Park, J. S., Kim, H. R. and Chae, H. J. (2018) Potential application of Ixeris dentata in the prevention and treatment of aging-induced dry mouth. Nutrients. 10: 1989.   DOI
10 Shin, S. A., Lee, H. N., Choo, G. S., Kim, H. J., Che, J. H. and Jung, J. Y. (2017) Ixeris dentata (Thunb. Ex Thunb.) Nakai extract inhibits proliferation and induces apoptosis in breast cancer cells through Akt/NF-${\kappa}B$ pathways. Int. J. Mol. Sci. 18: 275.   DOI
11 Li, L., Liu, C., Liu, Z., Tsao, R. and Liu, S. (2009) Identification of phenylethanoid glycosides in plant extract of Plantago asiatica L. by liquid chromatography-electrospray ionization mass spectrometry. Chin. J. Chem. 27: 541-545.   DOI
12 Yoon, M. Y., Kim, H. J. and Lee, S. J. (2019) The effect of antioxidant and whitening action on Plantago asiatica L. leaf ethanol extract for health care. Technol. Health Care. 27: 567-577.   DOI
13 Huang, D. F., Xie, M. Y., Yin, J. Y., Nie, S. P., Tang, Y. F., Xie, X. M. and Zhou, C. (2009) Immunomodulatory activity of the seeds of Plantago asiatica L. J. Ethnopharmacol. 124: 493-498.   DOI
14 Kim, B. H., Park, K. S. and Chang, I. M. (2009) Elucidation of anti-inflammatory potencies of Eucommia ulmoides bark and Plantago asiatica seeds. J. Med. Food. 12: 764-769.   DOI
15 Lee, S. S., Kim, D. H., Yim, D. S. and Lee, S.Y. (2007) Anti-Inflammatory, analgesic and hepatoprotective effect of semen of Rumex crispus. Kor. J. Pharmacogn. 38: 334-338.
16 Murai, M., Tamayama, Y. and Nishibe, S. (1995) Phenylethanoids in the herb of Plantago lanceolata and inhibitory effect on arachidonic acid-induced mouse ear edema. Planta Med. 61: 479-480.   DOI
17 Hong, S. H., Oh, G. W., Kang, W. G. and Kim, O. J. (2016) Anticoccidial effects of the Plantago asiatica extract on experimental Eimeria tenella infection. Lab. Anim. Res. 32: 65-69.   DOI
18 Uzun, M. and Demirezer, L. O. (2019) Anti-aging power of Rumex crispus L.: Matrixmetalloproteinases inhibitor, sun protective and antioxidant. S. Afr. J. Bot. 124: 364-371.   DOI
19 Park, J. A., Choi, M. O. and Kim, H. S. (2010) An analysis on physical and chemical features and components of each part of the Rumex crispus L. Asian J. Beauty Cosmetol. 8: 193-201.
20 Cho, Y. B., Kim, J. Y., Kwon, N. W., Hwang, B. Y., Kim, J. G., Woo, S. H. and Lee, M. S. (2019) Purification and identification of cytotoxic compounds from the root of Rumex crispus L. Korean J. Med. Crop Sci. 27: 208-217.   DOI
21 Park, E. S., Song, G. H., Kim, S. H., Lee, S. M., Kim, Y. G., Lim, Y. I., Kang, S. A. and Park, K. Y. (2018) Rumex crispus and Cordyceps militaris mixture ameliorates production of pro-inflammatory cytokines induced by lipopolysaccharide in C57BL/6 mice splenocytes. Prev. Nutr. Food Sci. 23: 374-381.   DOI
22 Park, S. J., Choi, J. H., Jung, Y. S. and Yu, M. H. (2013) Inhibitory effect of Rumex crispus L. fraction on adipocyte differentiation in 3T3-L1 cells. Korean J. Food Sci. Technol. 45: 90-96.   DOI
23 Guo, S., Feng, B., Zhu, R., Ma, J. and Wang, W. (2011) Preparative isolation of three anthraquinones from Rumex japonicus by high-speed counter-current chromatography. Molecules. 16: 1201-1210.   DOI
24 Shiwani, S., Singh, N. K. and Wang, M. H. (2012) Carbohydrase inhibition and anti-cancerous and free radical scavenging properties along with DNA and protein protection ability of methanolic root extracts of Rumex crispus. Nutr. Res. Pract. 6: 389-395.   DOI
25 Jeong, G. T., Lee, K. M. and Park, D. H. (2006) Study of antimicrobial and antioxidant activities of Rumex crispus extract. Korean Chem. Eng. Res. 44: 81-86.
26 Liu, W., Nisar, M. F. and Wan, C. (2020) Characterization of phenolic constituents from Prunus cerasifera Ldb leaves. J. Chem. 2020: 1-5.
27 Geng, F., Yang, L., Chou, G. and Wang, Z. (2010) Bioguided isolation of angiotensin-converting enzyme inhibitors from the seeds of Plantago asiatica L. Phytother. Res. 24: 1088-1094.   DOI
28 He, F., Chen, L., Liu, Q., Wang, X., Li, J. and Yu, J. (2018) Preparative separation of phenylethanoid and secoiridoid glycosides from ligustri lucidi fructus by high-speed counter-current chromatography coupled with ultrahigh pressure extraction. Molecules. 23: 3353.   DOI
29 Silinsin, M. and Bursal, E. (2018) UHPLC-MS/MS phenolic profiling and in vitro antioxidant activities of Inula graveolens (L.) Desf. Nat. Prod. Res. 32: 1467-1471.   DOI
30 Li, Y., Gan, L., Li, G. Q., Deng, L., Zhang, X. and Deng, Y. (2014) Pharmacokinetics of plantamajoside and acteoside from Plantago asiatica in rats by liquid chromatography-mass spectrometry. J. Pharm. Biomed. Anal. 89: 251-256.   DOI
31 Ham, H. N., Shrestha, A. C., Kim, J. E., Lee, T. B., Yoo, B. W., Kim, M. S., Kim, K. S., Lee, Y. M., Kim, J. Y. and Leem, J. Y. (2018) Simultaneous analysis of the compounds of natural cosmetic resources containing Chrysanthemum zawadskii, Perilla frutescens, Rosa multiflora and their antioxidative activity. Kor. J. Pharmacogn. 49: 312-321.
32 Chen, X., Tong, L., Wang, X., Zhang, L., Ma, X., Zhou, S. and Liu, C. (2013) Identification and characterization of anthraquinones in Cassia tora L. by liquid chromatography connected with time of flight mass spectrometry and ion trap mass spectrometry. Asian J. Chem. 25: 7840-7842.   DOI
33 Han, S. K., Kim, H. T., Kim, Y. M., Park, S. M., Lee, J. N., Oh, S. H. and Ha, H. Y. (2016) Improvement of dermal compactness by mixed extracts of three medicinal herbs. J. Invest. Cosmetol. 12: 221-225.   DOI