Browse > Article
http://dx.doi.org/10.22889/KJP.2020.51.3.207

Analysis of Pesticides in Herbal Medicine by QuEChERS and GC-MS/MS  

Seo, Go Eun (Bio-Center, Dongshin University)
Kim, A Young (Bio-Center, Dongshin University)
Pyo, Byoung Sik (Department of Oriental medicine materials, Dongshin University)
Lee, Kyoung in (Bio-Center, Dongshin University)
Publication Information
Korean Journal of Pharmacognosy / v.51, no.3, 2020 , pp. 207-216 More about this Journal
Abstract
The analysis method for qualitative analysis of the screening method that can be performed prior to the quantitative analysis of individual pesticide was reviewed in order to meet the safety standards that are being strengthened in the field of pesticide residue testing of herbal medicines. Among the residual pesticides presented in the Korean Pharmacopoeia, 56 pesticides, excluding 15 pesticides that need to be individually analyzed, were selected for analysis using QuEChERS preprocessing and GC-MS/MS, which are used in the existing agricultural products field. For each pesticide, the detection limit level of 0.001-0.005 mg/kg and the quantitative limit level of 0.002-0.017 mg/kg were confirmed. In the recovery test in which the standard was treated at a concentration of 0.02 mg/kg, it was confirmed that the proportion of pesticides satisfying the recovery of 70-120% was 85.7-96.4% for each herbal medicine, so it was confirmed that it was a level that could be reviewed by the screening method.
Keywords
Pesticides; QuEChERS; Herbal medicine; GC-MS/MS;
Citations & Related Records
Times Cited By KSCI : 9  (Citation Analysis)
연도 인용수 순위
1 Ahn, K. G., Kim, G. P., Hwang, Y. S., Kang, I. K., Lee, Y. D. and Choung, M. G. (2018) Simultaneous pesticide analysis method for bifenox, ethalfluralin, metolachlor, oxyfluorfen, pretilachlor, thenylchlor and trifluralin residues in agricultural commodities using GC-ECD/MS. Korean J. Environ. Agric. 37: 104-116.   DOI
2 Fu, Y., Dou, X., Zhang, L., Qin, J., Yang, M. and Luo, J. (2019) A comprehensive analysis of 201 pesticides for different herbal species-ready application using gas chromatography-tandem mass spectrometry coupled with QuEChERs. J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. 1125: 121730.   DOI
3 Lee, H. K., Oh, M. S., Jeong, J. A., Kim, K. Y., Lee, S. B., Kim, H. T., Kang, H. R., Son, J. H., Lee, Y. M., Lee, M. K., Lee, B. H., Kim, J. W. and Park, Y. B. (2019) A safety survey on pesticide residues in dried agricultural products. J. Food Hyg. Saf. 34: 340-347.   DOI
4 Ahn, K. G., Kim, G. H., Kim, G. P., Kim, M. J., Hwang, Y. S., Hong, S. B., Lee, Y. D. and Choung, M. G. (2014) Determination of amisulbrom residues in agricultural commodities using HPLC-UVD/MS. Korean J. Pestic. Sci. 18: 321-329.   DOI
5 Hwang, J. I., Jeon, Y. H., Kim, H. Y., Kim, J. H., Ahn, J. W., Seok, D. R., Lee, Y. J., Park, J. Y., Kim, D. H. and Kim, J. E. (2011) Improvement of analytical method for residue pesticides in herbal medicines using macroporous diatomaceous earth column. Korean J. Pestic. Sci. 15: 140-148.
6 Lee, J. H., Lee, Y. J., Kang, I. H., Kim, D. H., Kang, S. J., An, K. A., Lee, R. K., Suh, S. C. and Lee, J. R. (2014) Analytical methods of fenpyroximate in herbal medicines. Korean J. Pestic. Sci. 18: 141-147.   DOI
7 Jeong, H. Y., Noh, H. H., Lee, J. Y., Park, H. K., Jin, M. J., Kim, J. C., Hong, S. M. and Kyung, K. S. (2017) Residual characteristics and safety assessments of bifenthrin, carbendazim and metconazole in Angelica gigas Nakai. Korean J. Pestic. Sci. 21: 97-105.   DOI
8 Na, E. S., Kim, S. S., Hong, S. S., Kim, K. J., Lee, Y. J., Lee, B. C. and Lee, S. K. (2020) Development of multi-residue analytical method for 261 pesticides in herbal medicines using GC-MS/MS and LC-MS/MS. Korean J. Environ. Agric. 39: 142-169.   DOI
9 Park, J. W., Kim, A. K., Kim, J. P., Lee, H. H., Park, D. W., Moon, S. J., Ha, D. Y. and Seo, K. W. (2014) Multi-residue analysis of pesticides using GC-TOF/MS, ECD, NPD with QuEChERS sample preparation. Korean J. Pestic. Sci. 18: 278-295.   DOI
10 식품의약품안전처 (2017) 식품공전 잔류농약 분석법 실무해설서. 식품의약품안전처 고시 제2017-57호.
11 식품의약품안전처 (2019) 대한민국약전 제 12 개정. 식품의약품안전처 고시 제2019-102호.
12 식품의약품안전처 (2020) 식품의 기준 및 규격 일부 개정. 식품의약품안전처 고시 제2020-3호.
13 Yu, I. S., Park, S. K., Choi, Y. H., Seoung, H. J., Jung, H. J., Han, S. H., Lee, Y. J., Kim, Y. H., Kim, K. S., Han, K. Y. and Chae, Y. Z. (2012) Monitoring of pesticide residues in dried medicinal plants used for food materials. J. Food Hyg. Saf. 27: 224-232.   DOI
14 식품의약품안전처 (2015) 식품의 기준 및 규격 일부 개정. 식품의약품안전처 고시 제2015-78호.
15 Kang, H. R., Park, Y. B., Do, Y. S., Jeong, J. A., Lee, S. B., Cho, S. H., Lee, H. K., Son, J. H., Lee, M. K., Lee, B. H., Park, J. H. and Yoon, M. H. (2018) A safety survey on pesticide residues in tropical fruits depending on implementation of positive list system. J. Food Hyg. Saf. 33: 310-315.   DOI