Anti-inflammatory Effects of the Methanol Extracts of Phlox subulata on LPS-induced RAW264.7 Macrophages and BV2 Microglia |
Kim, Kwan-Woo
(College of Pharmacy, Wonkwang University)
Li, Jing (College of Pharmacy, Wonkwang University) Lee, Hwan (College of Pharmacy, Chosun University) Lee, Dong-Sung (College of Pharmacy, Chosun University) Oh, Hyuncheol (College of Pharmacy, Wonkwang University) Kim, Youn-Chul (College of Pharmacy, Wonkwang University) |
1 | Nathan, C. (2002) Points of control in inflammation. Nature 430: 846-852. DOI |
2 | Zhu, T., Zhang, W., Feng, S. J. and Yu, H. P. (2016) Emodin suppresses LPS-induced inflammation in RAW264.7 cells through a -dependent pathway. Int. Immunopharmacol. 34: 16-24. DOI |
3 | Zhang, H., Shan, Y., Wu, Y., Xu, C., Yu, X., Zhao, J., Yan, J. and Shang, W. (2017) Berberine suppresses LPS-induced inflammation through modulating Sirt1/NF- signaling pathway in RAW264.7 cells. Int. Immunopharmacol. 52: 93-100. DOI |
4 | Lull, M. E. and Block, M. L. (2010) Microglial activation & chronic neurodegeneration. Neurotherapeutics 7: 354-365. DOI |
5 | Romero, J. B. (1954) The Botanical Lore of the California Indians. Vantage Press. pp 59. |
6 | Enomoto, H., Kohata, K., Nakayama, M., Yamaguchi, Y. and Ichimura, K. (2004) 2-C-methyl-D-erythritol is a major carbohydrate in petals of Phlox subulata possibly involved in flower development. J. Plant. Physiol. 161: 977-980. DOI |
7 | Qu, Y., Zhou, A., Zhang, X., Tang, H., Liang, M., Han, H. and Zuo, Y. (2015) De novo transcriptome sequencing of low temperature-treated Phlox subulata and analysis of the genes involved in cold stress. Int. J. Mol. Sci. 16: 9732-9748. DOI |
8 | Zhou, A., Sun, H., Feng, S., Zhou, M., Gong, S., Wang, J. and Zhang, S. (2018) A novel cold-regulated gene from Phlox subulata, PsCor413im1, enhances low temperature tolerance in Arabidopsis. Biochem. Biophys. Res. Commun. 495: 1688-1694. DOI |
9 | Sharma, J. N., Al-Omran, A. and Parvathy, S. S. (2007) Role of nitric oxide in inflammatory diseases. Inflammopharmacology 15: 252-259. DOI |
10 | Ko, W., Sohn, J. H., Jang, J. H., Ahn, J. S., Kang, D. G., Lee, H. S., Kim, J. S., Kim, Y. C. and Oh, H. (2016) Inhibitory effects of alternaramide on inflammatory mediator expression through TLR4-MyD88-mediated inhibition of NF- and MAPK pathway signaling in lipopolysaccharide-stimulated RAW264.7 and BV2 cells. Chem. Biol. Interact. 244: 16-26. DOI |
11 | Tang, Y. and Le, W. (2016) Differential roles of M1 and M2 microglia in neurodegenerative diseases. Mol. Neurobiol. 53: 1181-1194. DOI |
12 | Andreasson, K. (2010) Emerging roles of receptors in models of neurological disease. Prostaglandins Other Lipid Mediat. 91: 104-112. DOI |
13 | Ikeda-Matsuo, Y. (2017) The Role of mPGES-1 in Inflammatory Brain Diseases. Biol. Pharm. Bull. 40: 557-563. DOI |
14 | Dong, C., Davis, R. J. and Flavell, R. A. (2002) MAP kinases in the immune response. Annu. Rev. Immunol. 20: 55-72. DOI |
15 | Pierre, C., Guillebaud, F., Airault, C., Baril, N., Barbouche, R., Save, E., Gaige, S., Bariohay, B., Dallaporta, M. and Troadec, J. D. (2018) Invalidation of microsomal prostaglandin E synthase-1 (mPGES-1) reduces diet-induced low-grade inflammation and adiposity. Front Physiol. 9: 1358. DOI |
16 | Du, R. W., Du, R. H. and Bu, W. G. (2014) -Arrestin 2 mediates the anti-inflammatory effects of fluoxetine in lipopolysaccharide-stimulated microglial cells. J. Neuroimmune Pharmacol. 9: 582-590. DOI |
17 | Viatour, P., Merville, M. P., Bours, V. and Chariot, A. (2005) Phosphorylation of NF-kappaB and IkappaB proteins: implications in cancer and inflammation. Trends Biochem. Sci. 30: 43-52. DOI |
18 | Li, C., Li, L., Chen, K., Wang, Y., Yang, F. and Wang, G. (2019) UFL1 alleviates lipopolysaccharide-induced cell damage and inflammation via regulation of the TLR4/NF- pathway in bovine mammary epithelial cells. Oxid. Med. Cell. Longev. 2019: 6505373. DOI |
19 | Kim, B. W., Koppula, S., Hong, S. S., Jeon, S. B., Kwon, J. H., Hwang, B. Y., Park, E. J. and Choi, D. K. (2013) Regulation of microglia activity by glaucocalyxin-A: attenuation of lipopolysaccharide-stimulated neuroinflammation through NF- and p38 MAPK signaling pathways. PLoS One 8: e55792. DOI |
20 | Liu, Y., Shepherd, E. G. and Nelin, L. D. (2007) MAPK phosphatases--regulating the immune response. Nat. Rev. Immunol. 7: 202-212. DOI |
21 | Lai, J. L., Liu, Y. H., Liu, C., Qi, M. P., Liu, R. N., Zhu, X. F., Zhou, Q. G., Chen, Y. Y., Guo, A. Z. and Hu, C. M. (2017) Indirubin inhibits LPS-induced inflammation via TLR4 abrogation mediated by the NF- and MAPK signaling pathways. Inflammation 40: 1-12. DOI |
22 | Yin, P., Zhang, Z., Li, J., Shi, Y., Jin, N., Zou, W., Gao, Q., Wang, W. and Liu, F. (2019) Ferulic acid inhibits bovine endometrial epithelial cells against LPS-induced inflammation via suppressing NK- and MAPK pathway. Res. Vet. Sci. 126: 164-169. DOI |