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Changes in Ginsenosides Composition of Ginseng Leaf and Stem after an Ultrasonication Process  

Nam, Yun Min (The Department of Oriental Medical Food & Nutrition, Semyung University)
Shin, Ho June (The Department of Oriental Medical Food & Nutrition, Semyung University)
Yang, Byung Wook (Korean Ginseng Research Co. Ltd)
Park, Jong Dae (Korean Ginseng Research Co. Ltd)
Cho, Soon Hyun (Department of Pharmaceutical Quality Control, Daewon University College)
Kim, Hyoung Chun (College of Pharmacy, Kangwon National University)
Ko, Sung Kwon (The Department of Oriental Medical Food & Nutrition, Semyung University)
Publication Information
Korean Journal of Pharmacognosy / v.47, no.4, 2016 , pp. 352-359 More about this Journal
Abstract
The purpose of this study is to develop a new preparation process of ginseng leaf and stem extracts having high concentrations of ginsenoside Rg2, Rg3, Rg5, Rh1, a special component of red and black ginseng. Chemical transformation from ginseng saponin glycosides to prosapogenin was analyzed by the HPLC. Extracts of ginseng (Panax ginseng) leaf and stem were processed under several treatment conditions including ultrasonication treatments. The content of total saponin reached their heights at 17 hr (UGL-17) of ultrasonication treatment, followed by 16 hr (UGL-16) and 7 hr (UGL-7) of ultrasonication treatment at $100^{\circ}C$. UGL-17 findings show that the ginseng leaf and stem that had been processed with ultrasonication for 17 hours peaked in the level of Rg2, Rg3 and Rh1. In addition, UGL-16 contained ginsenoside Rg5 at high concentrations. It is thought that such results provide basic information in preparing ginseng leaf and stem extracts with functionality enhanced.
Keywords
Ginseng; Leaf; Ultrasonication; Ginsenoside Rg2; Rg3; Rh1;
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Times Cited By KSCI : 12  (Citation Analysis)
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