Browse > Article

Lifespan Extending Effects of Fractions of Red Bean Sprouts  

Lee, Eun Byeol (College of Pharmacy, Woosuk University)
Kim, Jun Hyeong (College of Pharmacy, Woosuk University)
Park, Jae Jun (College of Pharmacy, Woosuk University)
Shin, Moon Ki (College of Pharmacy, Woosuk University)
Lee, Jae Seung (College of Pharmacy, Woosuk University)
Xing, Ming Ming (College of Pharmacy, Woosuk University)
Cha, Youn-Soo (Dept. of Food Science and Human Nutrition, Chonbuk National University)
Kim, Mina (Dept. of Food Science and Human Nutrition, Chonbuk National University)
Song, Seuk Bo (Dept. of Functional Crop, National Institute of Crop Science, Rural Development Administration)
Kim, Dae Keun (College of Pharmacy, Woosuk University)
Publication Information
Korean Journal of Pharmacognosy / v.46, no.3, 2015 , pp. 214-222 More about this Journal
Abstract
Recently, many studies have focused on the aging and oxidative stress. Several papers reported that Vigna angularis has various biological properties including antiaging, antioxidative and anti-inflammatory activities. Methanol extract from the red bean sprouts was successively partitioned as n-hexane, methylene chloride, ethyl acetate, n-butanol and H2O soluble fractions. We had studied lifespan extending and stress resistant effects of the fractions using Caenorhabditis elegans. Superoxide dismutase (SOD), catalase activities, and intracellular reactive oxygen species (ROS) levels were also investigated. Moreover, we had studied to find any significant change in aging-related factors such as reproduction, food intake, growth and movement of C. elegans. Our results represent that ethyl acetate fraction showed the most potent lifespan extending and stress resistant effects, and this fraction was able to elevate SOD and catalase activities of worms, and reduce intracellular ROS accumulation.
Keywords
Red bean sprouts; Vigna angularis; Caenorhabditis elegans; Lifespan. Oxidative stress;
Citations & Related Records
연도 인용수 순위
  • Reference