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Effects of Allium hookeri on Lipid Metabolism in Type II Diabetic Mice  

Lee, Seon-Hye (Functional Food & Nutrition Division, Department of Agro-food Resources, Rural Development Administration)
Kim, Nam-Seok (Functional Food & Nutrition Division, Department of Agro-food Resources, Rural Development Administration)
Choi, Bong-Kyoum (Functional Food & Nutrition Division, Department of Agro-food Resources, Rural Development Administration)
Jang, Hwan-Hee (Functional Food & Nutrition Division, Department of Agro-food Resources, Rural Development Administration)
Kim, Jung-Bong (Functional Food & Nutrition Division, Department of Agro-food Resources, Rural Development Administration)
Lee, Young Min (Department of Food and Nutrition, Seoul Women’s University)
Kim, Dae Keun (College of Pharmacy, Woosuk University)
Lee, Chang-Hyun (College of Oriental Medicine, Woosuk University)
Kim, You-Suk (Sunchang County Agricultural Research Center)
Yang, Jae-Heon (Center For Healthcare Technology Development, Chonbuk National University)
Kim, Young-Soo (Department of Food Science and Technology, Chonbuk National University)
Kim, Hyun-Ju (Research Department, World Institute of Kimchi)
Lee, Sung-Hyen (Functional Food & Nutrition Division, Department of Agro-food Resources, Rural Development Administration)
Publication Information
Korean Journal of Pharmacognosy / v.46, no.2, 2015 , pp. 148-153 More about this Journal
Abstract
Allium hookeri is a plant species native to India, Sri Lanka, Myanmar, and China. The plant is widely cultivated in Korea lately as a medicinal food item. This study was conducted to evaluate the effects of Allium hookeri (A. hookeri) on lipid metabolism in Type II diabetic mice (n=8/group, 5 groups). High fat diets with dextrin as a positive control (Dex), leaf (AL), root (AR), and fermented root (FAR) at 3% of diet were fed to all experimental mouse, respectively for 8 weeks. Body weight gain, liver and epididymal fat weights, and excreted fecal lipid levels were measured. Serum and hepatic lipid profiles were analyzed, and fat accumulation in liver was evaluated. In this study, body weight gain and epididymal fat weight were lower in the FAR group, while serum HDL-cholesterol level and excreted fecal total lipid and triglyceride levels were higher in AL or FAR groups. These results suggest that A. hookeri, specially fermented root can be a useful food item to control lipid metabolism in diabetic mice.
Keywords
Allium hookeri; Diabetic mice; Lipid; Metabolism; Diet;
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