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Functional Properties and Biological Activity of Breeding Lines, Parts, and Various solvents from Acanthopanax  

Jeong, Ji-Eun (Jeonnam Forest Resources Research Institute)
Baek, Hyo-Eun (Jeonnam Forest Resources Research Institute)
Oh, Duk-Sil (Jeonnam Forest Resources Research Institute)
Wi, An-Jin (Jeonnam Forest Resources Research Institute)
Yoon, Byeong-Sun (Jeonnam Forest Resources Research Institute)
Publication Information
Korean Journal of Pharmacognosy / v.44, no.3, 2013 , pp. 242-252 More about this Journal
Abstract
This study was evaluated to biological activity of breeding lines from Acantopanax( A. sessiliflorus: ASF, A. koreanum: AKN, A. chiicanensis: ACS, A. senticosus: AST) and parts(root, stem, fruit, and leaf) and various extracted solvents( 100% water, 100% EtOH, 50% EtOH). Total polyphenol content of AKN root in 100% water extracts was high detected 464.46 mg/100 g. Total flavonoid content in the leaf was significantly higher than in other parts. The content of total sugars was high in the 50% EtOH extracts and fruit. The major free amino acids were arginine in all extracts. The content of arginine was detected in the root of AKN(1.807 mg/100 mg). Contents of eleutheroside B, E were high detected in 100% water extracts. Antioxidative capacity in the leaves of AKN was the higher than other extracts($EC_{50}=84.8{\mu}g/mL$). The results would be useful for understanding of the physiological properties of AKN extracts.
Keywords
Acanthopanax; breeding lines; parts; solvent extraction; biological activity;
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1 Lee, Y. S., Jung, S. H., Lim, S. S., Ji, J., Lee, S. H. and Shin, K. H. (2001) Effects of the water extract from the stem bark of Acanthopanax senticosus on hyperlipidemia in rats. Kor. J. Pharmacogn. 21: 103-107.
2 Ko, S. K., Kim, J. S., Choi, Y. E., Lee, S. J., Park, K. S. and Chung, S. H. (2002) Anti-diabetic effects of mixed water extraction from Gingseng Radix rubra Acanthopanacis cortex and cordyceps. Kor. J. Pharmacogen. 33: 337-342.
3 Yook, C. S., Ryo, Y. S., Seo, S. H., Leem, J. Y. and Han, D. R. (1996) Chemical components of Acanthopanax divaricatus and anticancer effect in leaves. Yakhak hoeji. 40: 251-261.
4 Ko, S. T., Kim, S. W. and Lim, D. Y. (1978) A study on the hypotensive action of Acanthopanax extract in rabbit. Kor. J. Pharm. Sci. 8: 6-16.
5 Kim, S. K., Kim, Y. G., Lee, M. K., Han, J. S., Lee, J. H. and Lee, H. Y. (2000) Comparison of biological activity according to extracting solvents of four Acanthopanax root bark. Kor. J. Med. Crop. Sci. 8: 21-28.
6 Lim, J. K., Seo, Y. B., Kim, D. H. and Seol, I. C. (2000) The experimental studies on th- reinforcemental effects of Acanthopanax radicis Cortex about immunity hematogenic action. Kor. J. Herbolohy. 15: 1-17.
7 Kim, L. H., Han, S. S. and Choi, Y. S. (2002) Antioxidant effects of the extracts of Acanthopanax senticosus. Kor. J. Pharmacogn. 32: 103-107.
8 Yoon, T. J., Lee, S. W., Shin, K. S., Choi, W. H., Hwang, S. H., Seo, S. H., Kim, S. H. and Park, W. M. (2002) Effect of hot water extract from Acanthopanax senticosus on systemic anaphylaxis. Kor. J. Food Sci. Technol. 34: 518-523.
9 Park, J. H., Lee, H. S., Nun, H. C., Kim, D. H., Seong, N. S., Jung, H. G. and Lee, H. Y. (2004) Improvement of anticancer activation of ultrasonificated extracts from Acanthopanax senticosus Harms, Ephedra sinica Stapf, Rubus coreanus Miq. and Artemisia capillaris Thunb. Kor. J. Med. Crop. Sci. 12: 273-278.
10 Sawada, H., Miyakoshi, M., Isoda, S., Ida, Y. and Shoji, J. (1993) Saponins from leaves of Acanthopanax sieboldianus. Phytochemistry. 34: 1117-1121.   DOI
11 Nishib, S., Kinoshita, H., Takeda, H. and Okano, G. (1990) Phenolic compounds from stem bark of Acanthopanax senticosus and their pharmacological effect in chronic swimming rats. Chem. Pharm. Bull. 38: 1763-1765.   DOI
12 Zhao, Y. Q., Yang, S. S., Liu, J. H. and Zhao, G. R. (1993) Chemical constituents of Acanthopanax senticosus (Rupt. et Maxim.) Harms. Zhongguo Zhong Yao Za Zhi 18: 428-429.
13 Wang, J. Z., Tasumura, H., Shimura, K. and Ito, H. (1992) Antitumor activity of polysaccharide from a Chinese medicinal herb Acanthopanax giraldii Harms. Cancer Lett 65: 79-84.   DOI
14 Kohda, H., Tanaka, S. and Yamaoka, Y. (1990) Saponins from leaves of Acanthopanax hypoleeucus Makino. Chem. Pharm. Bull. 38: 3380-3383.   DOI
15 Wagner, H., Heur, Y. H., Obermeier, A., Tittle, G. and Bladt, S. (1982) Die DC- and HPLC-analyse der Eleutherococcus droge. Planta Med 44: 193-198.   DOI
16 Cai, X. F., Shen, G. D., Nguyentien, K., Kim, J. A., Lee, Y. M., Lee, J. J. and Kim, Y. H. (2003) Inhibitory Effect of TNF-$\alpha$ and IL-8 Secretion by Pimarane-Type Diterpenoids from Acanthopanax koreanum. Chem. Pharm. Bull. 51: 605-607.   DOI
17 Chung, H. S. and Youn, K. S. (2005) Changes of Physicochenica Characteristics of Acanthopanax senticosus Extract during Storage. Kor. J. Food Preserv. 12: 204-208.
18 Chang, C. C., Yang, M. H., Wen, H. M. and Chern, J. C. (2002) Estimation of total flavonoid content in propolis by two complementary colorimetric methods. Kor. J. Food Drug Anal. 10: 178-182.
19 Kim, K. B., Yoo, K. H., Park, H. Y., Jeong. J. M. (2006) Antioxidative activities of commercial edible plant extracts distributed in Korea. Kor Soc Appl Biol Chem. 49: 328-333.
20 Lim, J. H., Yang, Y. T. and Koh, J. S. (2007) Extraction of major constituents from Acanthopanax koreanum stems with water and ethanol solutions. Kor. J. Food Preserv. 14: 67-72.
21 Choi, Y. H. and Kim, J. W. (2002) Qyantitative analysis of eleutheroside B and E using HPLC-ESI/MS. Kor. J. Pharmacogn. 33: 88-91.
22 Lee, S. H., Kang, S. S., Cho, S. H., Ryu, S. N. and Lee, B. J. (2005) Determination of eleutherosides B and E in various parts of Acanthopanax species. Kor. J. Pharmacogn. 36: 70-74.