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Ingredients of Tyrosinase and Elastase Inhibitory Activity from Calyx of Diospyros kaki Thunberg  

Cha, Bae Cheon (Department of Pharmaceutical Engineering, College of Health Sciences, Sangji University)
Lee, Eun Hee (Department of Pharmaceutical Engineering, College of Health Sciences, Sangji University)
Publication Information
Korean Journal of Pharmacognosy / v.44, no.2, 2013 , pp. 182-187 More about this Journal
Abstract
This study was conducted to investigate glutathione S-transferase(GST) activity, tyrosinase inhibitory effect and elastase inhibitory effect in persimmon calyx(calyx of Diospyros kaki Thunberg) for screening of functional materials from natural products. As a result, EtOAc extract of persimmon calyx turned out to be having tyrosinase inhibitory effect and elastase inhibitory effect. The active constituents of tyrosinase and elastase inhibitory effect were isolated from EtOAc extract of persimmon calyx. Their structure of compounds were identified as ursolic acid and (-)-daucosterol by spectroscopic evidence, respectively.
Keywords
Persimmon calyx; Calyx of Diospyros kaki Thunberg; Tyrosinase inhibitory effect; Elastase inhibitory effect; GST(glutathione S-transferase); Ursolic acid; Daucosterol;
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