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Protective efficacies of Aronia melanocarpa (Blackberry) on the Allyl Alcohol-damaged Hepatocyte of Mice  

Han, Sang-Zin (Department of Life science, Hallym University)
Publication Information
Korean Journal of Pharmacognosy / v.44, no.1, 2013 , pp. 91-96 More about this Journal
Abstract
The results of the alcohol decomposition ability of Aronia melanocarpa are as follows. Plasma alcohol concentration of the Aronia group was ca. 48.9% lower than the control group, but half an hour faster in that of Aronia before alcohol group, ca. 54.9% higher and half an hour later than that of the control group. ALDH(acetaldehyde dehydrogenase) of the Aronia group was ca. 243% higher than that of the control group. But maximal ALDH of the group taking Aronia before alcohol administration showed 0.5h faster and ca. 267% higher than that of the control group. This result shows that the activity of ALDH was increased by the Aronia. Aronia group's AST and ALT are increasing with similar patterns and their levels continually under the control's, but ca. 12.6% lower at AST and ca. 19.0% lower at ALT than those of control group. Ca. 21.7% lower at AST and ca. 40.5% lower at ALT in the Aronia group before alcohol administration than those of the control group. This result shows that Aronia has a role of suppressor against the liver damage. Therefore, this study proved lucidly the protective effects of Aronia on the hepatocyte.
Keywords
Aronia melanocarpa; Acetaldehyde; ALDH; AST; ALT;
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