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Antioxidant Constituents of the Aerial Parts of Curcuma longa  

Ahn, Dalrae (College of Pharmacy, Woosuk University)
Lee, Eun Byeol (College of Pharmacy, Woosuk University)
Ahn, Min-Sil (Jeollabuk-do Agricultural Research and Extension Servieces)
Lim, Hye Won (Bio Bldg.)
Xing, Ming Ming (College of Pharmacy, Woosuk University)
Tao, Chao (College of Pharmacy, Woosuk University)
Yang, Jae Heon (Center for Healthcare Technology Development, Chonbuk National University)
Kim, Dae Keun (College of Pharmacy, Woosuk University)
Publication Information
Korean Journal of Pharmacognosy / v.43, no.4, 2012 , pp. 274-278 More about this Journal
Abstract
As part of ongoing study focused on the discovery of natural antioxidants from Korean plants by measuring the DPPH (1,1-diphenyl-2-picrylhydrazyl) radical scavenging effect and superoxide quenching activity, ethanol extract of the aerial parts of Curcuma longa (Zingiberaceae) was found to show potent antioxidant activities. Subsequent activity-guided fractionation of the ethanol extract led to the isolation of two phenolic compounds, 1,2,3,4,6-penta-O-galloyl-${\beta}$-D-glucopyranoside (1) and gallic acid (2), as antioxidant compounds. Their structures were elucidated by spectroscopic studies. Compounds 1 and 2 were isolated for the first time from this plant. These compounds showed the significant antioxidative effects during the DPPH free radical scavenging test, and the riboflavin- and xanthine-originated superoxide quenching activity tests.
Keywords
Curcuma longa; Zingiberaceae; DPPH; Superoxide quenching activity;
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Times Cited By KSCI : 2  (Citation Analysis)
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1 Steinmetz, K. A. and Potter, J. D. (1991) Vegetables, fruit, and cancer. II. Mechanisms. Cancer Causes Contrl. 2: 427-442.   DOI   ScienceOn
2 Woo, K. S., Seo, M. C., Kang, J. R., Ko, J. Y., Song, S. B., Lee, J. S., Oh, B. G., Park, G. D., Lee, Y. H., Nam, M. H. and Jeong, H. S. (2010) Antioxidant compounds and antioxidant activities of the methanolic extracts from milling fractions of sorghum (Sorghum bicolor L. Moench). J. Korean Soc. Food Sci. Nutr. 39: 1695-1699.   DOI   ScienceOn
3 Yu, B. P. (1996) Aging and oxidative stress: modulation by dietary restriction. Free Radic. Biol. Med. 21: 651-668.   DOI   ScienceOn
4 Heo, C., Chung, J. H., Jo, B. K., Kim, H. P. and Heo, M. Y. (2003) Antioxidative activities of 60 plant extracts. The Journal of Applied Pharmacology 11: 196-199.
5 Heo, C., Chung, J. H., Jo, B. K., Kim, H. P. and Heo, M. Y. (2003) Antioxidative activities of 60 plant extracts. The Journal of Applied Pharmacology 11: 196-199.
6 Suk, S. H. (2006) Antioxidant effect of vitamin E on vascular endothelial cells damaged by reactive oxygen species. Korean J. Oriental Physiology & Pathology 20: 685-689.
7 한국약학대학협의회 약전분과회 편저 (2008) 대한약전해설서(9개정) II, 1098, 1161, 도서출판 신일북스, 서울.
8 Yoshida, T., Mori, K., Hatano, T., Okumura, T., Uehara, I., Komagoe, K., Fujita, Y. and Okuda, T. (1989) Studies on inhibition mechanism of autooxidation by tannins and flavonoids. V.- Radical scavenging effects of tannins and related polyphenols on 1,1-diphenyl-2-picrylhydrazyl radical. Chem. Pharm. Bull. 37: 1919-1921.   DOI
9 Choi, D. S., Kim, S. J., and Jung, M. Y. (2001) Inhibitory activity of berberine on DNA strand cleavage induced by hydrogen peroxide and cytochrome c. Biosci. Biotechnol. Biochem. 65: 452-455.   DOI   ScienceOn
10 Ginnopolitis, C. N. and Ries, S. K. (1977) Superoxide dismutase. I. Occurrence in higher plants. Plant Physiol. 59, 309-314.   DOI   ScienceOn
11 Thuong, P. T., Su, N. D., Ngoc, T. M., Hung, T. M., Dang, N. H., Thuan, N. D., Bae, K. H. and Oh, W. K. (2009) Antioxidant activity and principles of Vietnam bitter tea Ilex kudingcha. Food Chem. 113: 139-145.   DOI   ScienceOn
12 Kim, J. J., Lee, J. S., Kim S. Y., Kim, J. A., Chung, S. R., Jang, T. S. and Lee, S. H. (2001) Inhibitory effect of hydrolysable tannins isolated from the Euphorbia helioscopia on mushroom tyrosinase activity in vitro. Yakhak Hoeji 45: 214-219.
13 Kim, J. K., Kwon, D. J., Lim, S. S. and Bae, Y. S. (2010) Chemical constituents of domestic Quercus spp. barks. Mokchae Konghak 38: 359-374.
14 Park, W. Y., Lee, S. C., Ahn, B. T., Lee, S. H., Ro, J. S. and Lee, K. S. (1993) Phenolic compounds from Acalypha australis L. Kor. J. Pharmacogn. 24: 20-25.