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Screening of Antioxidative Activities and Antiinflammatory Activities in Local Native Plants  

Kim, Han-Hyuk (College of Pharmacy, Chung-Ang University)
Kwon, Joo-Hee (College of Pharmacy, Chung-Ang University)
Park, Kwan-Hee (College of Pharmacy, Chung-Ang University)
Kim, Manh-Heun (College of Pharmacy, Chung-Ang University)
Oh, Myoeng-Hwan (College of Pharmacy, Chung-Ang University)
Choe, Kang-In (College of Pharmacy, Chung-Ang University)
Park, Sang-Hee (College of Pharmacy, Chung-Ang University)
Jin, Hye-Young (Korea National Arboretum)
Kim, Sung-Sik (Korea National Arboretum)
Lee, Min-Won (College of Pharmacy, Chung-Ang University)
Publication Information
Korean Journal of Pharmacognosy / v.43, no.1, 2012 , pp. 85-93 More about this Journal
Abstract
181 kinds of local native plants were selected by its anti-inflammatorial folk medicinal uses and evaluated it antioxidative and inhibitory activity of nitric oxide (NO) production in lipopolysaccharide (LPS)-induced 264.7 macrophage cells. Among the 181 kinds of plants, 99 species showed potent antioxidative activities and 20 extracts showed inhibitory activity towards nitric oxide production by more than 70% at a concentration of $100{\mu}g/mL$. Therefore, these plants should be considered promising candidates for the treatment of inflammatory diseases accompanying overproduction of NO.
Keywords
Local native plants; Antioxidative; Anti-inflammatory; DPPH; NBT/XO; Nitric oxide;
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Times Cited By KSCI : 2  (Citation Analysis)
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