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Quantitative Determination of Lignans from Schizandra chinensis by HPLC  

Koo, Dong-Chil (School of Biotechnology, Yeungnam University)
Suh, Won-Se (School of Biotechnology, Yeungnam University)
Baek, So-Yoon (School of Biotechnology, Yeungnam University)
Shim, Sang-Hee (School of Biotechnology, Yeungnam University)
Publication Information
Korean Journal of Pharmacognosy / v.42, no.3, 2011 , pp. 233-239 More about this Journal
Abstract
A reversed phase HPLC method was established for quantitative determination of lignans including schizandrin (1), gomisin A (2), deoxyschizandrin (3), gomisin N (4), and wuweizisu C (5) from Schizandra chinensis using a binary gradient of acetonitrile and water as a mobile phase with UV detection at 254nm. In result, contents of schizandrin (1), gomisin A (2), deoxyschizandrin (3), gomisin N (4), and wuweizisu C (5) in Schizandra chinensis from Moonkyung were 8.41${\pm}$0.30, 3.01${\pm}$0.13, 1.06${\pm}$0.05, 7.69${\pm}$0.30, and 1.68${\pm}$0.06 mg/g, respectively.
Keywords
Schisandra chinensis; Quantitative analysis; Lignan; HPLC;
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