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Dihydrochalcone Components from the Twigs of Stewartia koreana  

Ahn, Dal-Rae (College of Pharmacy, Woosuk University)
Lee, Sa-Im (College of Pharmacy, Kyung Hee University)
Yang, Jae-Heon (College of Pharmacy, Woosuk University)
Im, Jong-Pil (College of Pharmacy, Woosuk University)
Jeon, Hun (College of Pharmacy, Woosuk University)
Eun, Jae-Sun (College of Pharmacy, Woosuk University)
Kim, Hak-Yong (College of Engineering, Chonbuk National University)
Lee, Jae-Hyeok (Dept. of Oriental Pharmaceutical Development, Nambu University)
Park, Jeong-Suk (Dept. of Complementary and Alternative Medicine, Nambu University)
Kim, Dae-Keun (College of Pharmacy, Woosuk University)
Publication Information
Korean Journal of Pharmacognosy / v.42, no.3, 2011 , pp. 229-232 More about this Journal
Abstract
Three dihydrochalcone compounds were isolated from the twigs of Stewartia koreana (Theaceae) through repeated column chromatography. Their chemical structures were elucidated as phloridizin, 2',4,4'-trihydroxy-6'-methoxydihydrochalcone and confusoside, respectively, by spectroscopic analysis. These compounds were isolated for the first time from this plant.
Keywords
Stewartia koreana; dihydrochalcone; phloridizin; 2',4,4'-trihydroxy-6'-methoxydihydrochalcone; confusoside;
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1 Valenta1, C., Cladera, J., O'Shea, P. and Hadgraft, J. (2001) Effect of phloretin on the percutaneous absorption of lignocaine across human skin. J. Pharm. Sci. 90: 485-492.   DOI   ScienceOn
2 Seidel, V., Bailleul, F. and Waterman, P. G. (2000) (Rel)-$1{\beta}$, $2{\alpha}$-di-(2,4-dihydroxy-6-methoxybenzoyl)-$3{\beta}$, $4{\alpha}$-di-(4-methoxyphenyl)- cyclobutane and other flavonoids from the aerial parts of Goniothalamus gardneri and Goniothalamus thwaitesii. Phytochemistry 55: 439-446.   DOI   ScienceOn
3 Agrawal, P. K. (1989) Carbon-13 NMR of flavonoids. In Agrawal, P. K. and Bansal, M. C., Chalconoids, 402, Elsevier, New York.
4 Gosch, C., Halbwirth, H. and Stich, K. (2010) Phloridzin: Biosynthesis, distribution and physiological relevance in plants. Phytochemistry 71: 838-843.   DOI   ScienceOn
5 Ehrenkranz, J. R. L., Lewis, N. G., Kahn, C. R. and Roth, J. (2005) Phlorizin: a review, Diabetes Metab. Res. Rev. 21: 31- 38.
6 Lu, Y. and Foo, Y. (1997) Identification and quantification of major polyphenols in apple pomace. Food Chem. 59: 187- 194.   DOI   ScienceOn
7 Mizuno, M., Kojima, H., Tanaka, T., Iinuma, M., Kimura, R., Zhi-Da, M and Murata, H. (1987) Phenolic constituents from seeds of Coptis japonica var. dissecta. Phytochemistry 26: 2071-2074.   DOI   ScienceOn
8 Lee, S. I., Yang, J. H. and Kim, D. K. (2010) Antioxidant flavonoids from the twigs of Stewartia koreana. Biomol. Ther. 18: 191-196.   DOI
9 Lee, T. B., (1986) Illustrated flora of Korea, 542, Hyangmoonsa, Seoul.
10 Lee, T. H., Lee, G. W., Kim, C. W., Bang, M. H., Baek, N. I., Kim, S. H., Chung, D. K. and Kim, J. (2010) Stewartia koreana extract stimulates proliferation and migration of human endothelial cells and induces neovasculization in vivo. Phytother. Res. 24: 20-25.   DOI   ScienceOn
11 Lee, W. T. (1996) Coloured standard illustrations of Korean plant, 127, Academy, Seoul.
12 Lee, T. H., Kwak, H. B., Kim, Kim H.-H., Lee, Z. H., Chung, D. K., Baek, N.-I. and Kim J. (2007) Methanol extracts of Stewartia koreana inhibit cyclooxygenase-2 (COX-2) and inducible nitric oxide synthase (iNOS) gene expression by blocking NF-kB transactivation in LPS-activated RAW 264.7 cells. Mol. Cells 23: 398-404.
13 Park, C. K., Kim, H. J., Kwak, H. B., Lee, T. H., Bang, M. H., Kim, C. M., Lee, Y., Chung, D. K., Baek, N. I., Kim, J., Lee, Z. H. and Kim, H. H. (2007) Inhibitory effects of Stewartia koreana on osteoclast differentiation and bone resorption. Int. Immunopharmacol. 7: 1507-1516.   DOI   ScienceOn