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Antibacterial Activity against Pathogens of Acne and Tyrosinase Inhibitory Activity of Extract and Fractions from Bark of Prunus sargentii  

Lee, Kyoung-In (Biotechnology Industrialization Center, Dongshin University)
Yang, Sun-Ah (Dept. of Oriental Medicine Materials, Dongshin University)
Pyo, Byoung-Sik (Dept. of Oriental Medicine Materials, Dongshin University)
Kim, Sun-Min (Dept. of Oriental Medicine Materials, Dongshin University)
Publication Information
Korean Journal of Pharmacognosy / v.42, no.2, 2011 , pp. 155-160 More about this Journal
Abstract
In this study, we investigated on antioxidative activity, antibacterial activity against pathogens of acne and tyrosinase inhibitory activity in 75% EtOH extract and its fractions from bark of Prunus sargen tii. The total polyphenol and flavonoidcontent of the EtOAc fraction were found to be 378.0 mg/g and 67.5 mg/g as the highest content. In the measurement of DPPH radical scavenging ability, EtOAc and BuOH fraction were exhibited stronger scavenging ability than the other fractions and 75% EtOH extract. In antibacterial activity by disc diffusion assay against pathogen of acne, antibacterial activity of the EtOAc fraction and 75% EtOH extract was stronger than the other fractions. Especially, the EtOAc fraction was the highest effective fraction in the antibacterial activity. Moreover, tyrosinase inhibitory activity of EtOAc fraction, BuOH fraction and 75% EtOH extract was higher than the other fractions. In particular, tyrosinase inhibitory activity of the EtOAc fraction showed higher activity than ascorbic acid used as positive control.
Keywords
Prunus sargentii; Antibacterial activity; Acne; tyrosinase;
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Times Cited By KSCI : 11  (Citation Analysis)
Times Cited By SCOPUS : 2
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